Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Asish R Chaudhuri"'
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143680 (2015)
Comparative aging studies, particularly those that include species of exceptional resistance to aging processes, can potentially illuminate novel senescence-retarding mechanisms. In recent years, protein homeostasis (proteostasis) has been implicated
Externí odkaz:
https://doaj.org/article/d6c38df5da0542f1af0b00c4f62e6749
Autor:
Ryan T Hamilton, Arunabh Bhattacharya, Michael E Walsh, Yun Shi, Rochelle Wei, Yiqiang Zhang, Karl A Rodriguez, Rochelle Buffenstein, Asish R Chaudhuri, Holly Van Remmen
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65725 (2013)
Diabetic peripheral polyneuropathy is associated with decrements in motor/sensory neuron myelination, nerve conduction and muscle function; however, the mechanisms of reduced myelination in diabetes are poorly understood. Chronic elevation of oxidati
Externí odkaz:
https://doaj.org/article/ef136193228547028492e1ff742a9359
Autor:
Jeongmoon J. Choi, Florian L. Muller, Holly Van Remmen, Asish R. Chaudhuri, Michael S. Lustgarten, Karl A. Rodriguez, Arlan Richardson, Arunabh Bhattacharya, Nan Hee Lee, Anson Pierce, Young C. Jang
Publikováno v:
GeroScience
The maintenance of skeletal muscle mass depends on the overall balance between the rates of protein synthesis and degradation. Thus, age-related muscle atrophy and function, commonly known as sarcopenia, may result from decreased protein synthesis, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47eb7aec7f1936ec47aca6c155ad8909
https://doi.org/10.1007/s11357-020-00200-5
https://doi.org/10.1007/s11357-020-00200-5
Autor:
Asish R. Chaudhuri, Rashmi Singh, Michael E. Walsh, Arunabh Bhattacharya, Ramaswamy Sharma, Md. Mizanur Rahman, Karl A. Rodriguez, Ryan T. Hamilton
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47edba9f3052e35b34d349f501aeb327
https://doi.org/10.1096/fasebj.2019.33.1_supplement.651.2
https://doi.org/10.1096/fasebj.2019.33.1_supplement.651.2
Publikováno v:
Biochemical and Biophysical Research Communications. 446:1250-1254
Our recent study in a mouse model of familial-Amyotrophic Lateral Sclerosis (f-ALS) revealed that muscle proteins are equally sensitive to misfolding as spinal cord proteins despite the presence of low mutant CuZn-superoxide dismutase, which is consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc7a3cb57d5fada0c4fa8949dfebdaf
https://doi.org/10.1016/j.bbrc.2014.03.097
https://doi.org/10.1016/j.bbrc.2014.03.097
Autor:
Asish R. Chaudhuri, Ryan T. Hamilton, Hanyu Liang, Rochelle Buffenstein, Anson Pierce, Eric de Waal
Publikováno v:
Biochemical and Biophysical Research Communications. 434:815-819
The 'oxidative stress theory of aging' predicts that aging is primarily regulated by progressive accumulation of oxidized macromolecules that cause deleterious effects to cellular homeostasis and induces a decline in physiological function. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab129d0588585a792ce23824929bf63
https://doi.org/10.1016/j.bbrc.2013.04.019
https://doi.org/10.1016/j.bbrc.2013.04.019
Autor:
Rashmi Singh, Ryan T. Hamilton, Xiaoli Gao, Md. Mizanur Rahman, Karl A. Rodriguez, Michael E. Walsh, Asish R. Chaudhuri, Arunabh Bhattacharya
Publikováno v:
Journal of the neurological sciences. 370
Aging is associated with a decline in peripheral nerve function of both motor and sensory nerves. The decline in function of peripheral sensorimotor nerves with aging has been linked to sarcopenia, the age-related decline in muscle mass and function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6c335da3683a56543f3f3e16de7578
https://pubmed.ncbi.nlm.nih.gov/27772785
https://pubmed.ncbi.nlm.nih.gov/27772785
Autor:
Wenbo Qi, Christopher R. Hayworth, Asish R. Chaudhuri, Arunabh Bhattacharya, Michael S. Lustgarten, Young C. Jang, Florian L. Muller, Eric Verdin, Yuhong Liu, Yan Li, Holly Van Remmen, Jing Yi Huang, Arlan Richardson
Publikováno v:
Aging Cell. 11:770-782
Age-related loss of muscle mass and function, sarcopenia, has a major impact on the quality of life in the elderly. Among the proposed causes of sarcopenia are mitochondrial dysfunction and accumulated oxidative damage during aging. Dietary restricti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd1d43116ef74a0a1972a6d6fede6314
https://doi.org/10.1111/j.1474-9726.2012.00843.x
https://doi.org/10.1111/j.1474-9726.2012.00843.x
Autor:
Junji Yodoi, Viviana I. Pérez, Wilson C. Fok, Holly Van Remmen, Asish R. Chaudhuri, Kaoru Tominaga, Lisa A. Cortez, Arlan Richardson, Christie M. Lew, Yuji Ikeno, Celeste R. Webb, Yiqiang Zhang, Dean P. Jones, Shuko Lee, Gene B. Hubbard, Wenbo Qi, Alex Bokov, Marisela Rodriguez
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. :1286-1299
We examined the effects of increased levels of thioredoxin 1 (Trx1) on resistance to oxidative stress and aging in transgenic mice overexpressing Trx1 [Tg(TRX1)(+/0)]. The Tg(TRX1)(+/0) mice showed significantly higher Trx1 protein levels in all the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaec96b95923f60c60c6e3f55a5c53bb
https://doi.org/10.1093/gerona/glr125
https://doi.org/10.1093/gerona/glr125
Autor:
Arlan Richardson, Asish R. Chaudhuri, Arunabh Bhattacharya, Suzette D. Tardif, Rochelle Buffenstein, Steven N. Austad, Kathleen E. Fischer, Shanique Leonard
Publikováno v:
Aging Cell. 10:720-723
Oxidative damage affects protein structure and function. Progressive accumulation of oxidized proteins is considered a putative mechanism of aging; however, empirical evidence supporting their role in aging is inconsistent. This inconsistency may ref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29ad29354ea03f89c2822ee2fb09500a
https://doi.org/10.1111/j.1474-9726.2011.00712.x
https://doi.org/10.1111/j.1474-9726.2011.00712.x