Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Asish Chudhuri"'
Autor:
Esmaeil Dehghan, Yiqiang Zhang, Bahar Saremi, Sivaramakrishna Yadavali, Amirmansoor Hakimi, Maryam Dehghani, Mohammad Goodarzi, Xiaoqin Tu, Scott Robertson, Rueyling Lin, Asish Chudhuri, Hamid Mirzaei
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Hydralazine is an FDA approved drug for the treatment of hypertension. Here, Dehghan et al. report that hydralazine triggers the cellular oxidative stress response by activating NRF2/SKN-1 signaling and extends C. elegans healthy lifespan, suggesting
Externí odkaz:
https://doaj.org/article/7fd249672058484eb42b4cddbf922c6e
Autor:
Amirmansoor Hakimi, Yiqiang Zhang, Mohammad Goodarzi, Bahar Saremi, Dehghani Maryam, Xiaoqin Tu, Scott M. Robertson, Asish Chudhuri, Hamid Mirzaei, Sivaramakrishna Yadavali, Esmaeil Dehghan, Rueyling Lin
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nuclear factor (erythroid-derived 2)-like 2 and its Caenorhabditis elegans ortholog, SKN-1, are transcription factors that have a pivotal role in the oxidative stress response, cellular homeostasis, and organismal lifespan. Similar to other defense s