Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Asisa Volz"'
Autor:
Leonie Mayer, Leonie M. Weskamm, Anahita Fathi, Maya Kono, Jasmin Heidepriem, Verena Krähling, Sibylle C. Mellinghoff, My Linh Ly, Monika Friedrich, Svenja Hardtke, Saskia Borregaard, Thomas Hesterkamp, Felix F. Loeffler, Asisa Volz, Gerd Sutter, Stephan Becker, Christine Dahlke, Marylyn M. Addo
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract In response to the COVID-19 pandemic, multiple vaccines were developed using platforms such as viral vectors and mRNA technology. Here, we report humoral and cellular immunogenicity data from human phase 1 clinical trials investigating two r
Externí odkaz:
https://doaj.org/article/5b1fea1ceb2340e395b1e673ec685d27
Autor:
Christian Meyer zu Natrup, Lisa-Marie Schünemann, Giulietta Saletti, Sabrina Clever, Vanessa Herder, Sunitha Joseph, Marina Rodriguez, Ulrich Wernery, Gerd Sutter, Asisa Volz
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 6, Pp 1236-1239 (2023)
We developed an ELISPOT assay for evaluating Middle East respiratory syndrome coronavirus (MERS-CoV)‒specific T-cell responses in dromedary camels. After single modified vaccinia virus Ankara-MERS-S vaccination, seropositive camels showed increased
Externí odkaz:
https://doaj.org/article/cf3fc1d60ad049a2b69d302403f46045
Autor:
Kim Thi Hoang Do, Stefanie Willenzon, Jasmin Ristenpart, Anika Janssen, Asisa Volz, Gerd Sutter, Reinhold Förster, Berislav Bošnjak
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Background and aimsModified Vaccinia virus Ankara (MVA) represents a promising vaccine vector for respiratory administration to induce protective lung immunity including tertiary lymphoid structure, the bronchus-associated lymphoid tissue (BALT). How
Externí odkaz:
https://doaj.org/article/de6be87cc416489f89eb6de74080f119
Autor:
Jeffy G. Mattathil, Asisa Volz, Olusegun O. Onabajo, Sean Maynard, Sandra L. Bixler, Xiaoying X. Shen, Diego Vargas-Inchaustegui, Marjorie Robert-Guroff, Celia Lebranche, Georgia Tomaras, David Montefiori, Gerd Sutter, Joseph J. Mattapallil
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Mucosal surfaces are a primary route of HIV entry, yet the compartmentalisation between mucosal and peripheral immune systems remain a challenge for HIV vaccine candidates. Authors utilise a combination of intranodal tonsil MALT and systemic vaccinat
Externí odkaz:
https://doaj.org/article/5c95e638f47643898cb93e8cea9c171f
Autor:
Sabrina Clever, Leonard Limpinsel, Christian Meyer zu Natrup, Lisa-Marie Schünemann, Georg Beythien, Malgorzata Rosiak, Kirsten Hülskötter, Katharina Manuela Gregor, Tamara Tuchel, Georgia Kalodimou, Astrid Freudenstein, Satendra Kumar, Wolfgang Baumgärtner, Gerd Sutter, Alina Tscherne, Asisa Volz
Publikováno v:
Viruses, Vol 16, Iss 3, p 417 (2024)
The sudden emergence of SARS-CoV-2 demonstrates the need for new vaccines that rapidly protect in the case of an emergency. In this study, we developed a recombinant MVA vaccine co-expressing SARS-CoV-2 prefusion-stabilized spike protein (ST) and SAR
Externí odkaz:
https://doaj.org/article/dce965dac07f41e881175ae99326794b
Autor:
Sabrina Clever, Lisa-Marie Schünemann, Federico Armando, Christian Meyer zu Natrup, Tamara Tuchel, Alina Tscherne, Malgorzata Ciurkiewicz, Wolfgang Baumgärtner, Gerd Sutter, Asisa Volz
Publikováno v:
Vaccines, Vol 12, Iss 1, p 52 (2024)
Aging is associated with a decline in immune system functionality. So-called immunosenescence may impair the successful vaccination of elderly people. Thus, improved vaccination strategies also suitable for an aged immune system are required. Modifie
Externí odkaz:
https://doaj.org/article/ef0ed1f946e847349fdcdb39a1bdf45f
Autor:
Anahita Fathi, Christine Dahlke, Verena Krähling, Alexandra Kupke, Nisreen M. A. Okba, Matthijs P. Raadsen, Jasmin Heidepriem, Marcel A. Müller, Grigori Paris, Susan Lassen, Michael Klüver, Asisa Volz, Till Koch, My L. Ly, Monika Friedrich, Robert Fux, Alina Tscherne, Georgia Kalodimou, Stefan Schmiedel, Victor M. Corman, Thomas Hesterkamp, Christian Drosten, Felix F. Loeffler, Bart L. Haagmans, Gerd Sutter, Stephan Becker, Marylyn M. Addo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
In a clinical trial, Fathi et al. show that a booster vaccination with a vector vaccine candidate against the highly pathogenic Middle East Respiratory Syndrome coronavirus is safe and strongly improves the immunity generated by primary immunization.
Externí odkaz:
https://doaj.org/article/9c0741a645df4990aa04ffff02338df4
Autor:
Christian Meyer zu Natrup, Alina Tscherne, Christine Dahlke, Malgorzata Ciurkiewicz, Dai-Lun Shin, Anahita Fathi, Cornelius Rohde, Georgia Kalodimou, Sandro Halwe, Leonard Limpinsel, Jan H. Schwarz, Martha Klug, Meral Esen, Nicole Schneiderhan-Marra, Alex Dulovic, Alexandra Kupke, Katrin Brosinski, Sabrina Clever, Lisa-Marie Schünemann, Georg Beythien, Federico Armando, Leonie Mayer, Marie L. Weskamm, Sylvia Jany, Astrid Freudenstein, Tamara Tuchel, Wolfgang Baumgärtner, Peter Kremsner, Rolf Fendel, Marylyn M. Addo, Stephan Becker, Gerd Sutter, Asisa Volz
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)
The SARS-CoV-2 spike (S) glycoprotein is synthesized as a large precursor protein and must be activated by proteolytic cleavage into S1 and S2. A recombinant modified vaccinia virus Ankara (MVA) expressing native, full-length S protein (MVA-SARS-2-S)
Externí odkaz:
https://doaj.org/article/c3dacfdcee5044c4a6d220158af4b33c
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss , Pp 399-409 (2021)
Recently, oncolytic vaccinia viruses (VACVs) have shown their potential to provide for clinically effective cancer treatments. The reason for this clinical usefulness is not only the direct destruction of infected cancer cells but also activation of
Externí odkaz:
https://doaj.org/article/c98f6cedfd73473a966eace4a8a80379
Autor:
Martin C. Langenmayer, Anna-Theresa Luelf-Averhoff, Lisa Marr, Sylvia Jany, Astrid Freudenstein, Silvia Adam-Neumair, Alina Tscherne, Robert Fux, Juan J. Rojas, Andreas Blutke, Gerd Sutter, Asisa Volz
Publikováno v:
Pathogens, Vol 12, Iss 7, p 867 (2023)
Influenza, a respiratory disease mainly caused by influenza A and B, viruses of the Orthomyxoviridae, is still a burden on our society’s health and economic system. Influenza A viruses (IAV) circulate in mammalian and avian populations, causing sea
Externí odkaz:
https://doaj.org/article/ed108fa0846b4fb79076124651caa712