Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Asima Chakraborty"'
Autor:
Asima Chakraborty, Daniel A Pasek, Tai-Qin Huang, Angela C Gomez, Naohiro Yamaguchi, Mark E Anderson, Gerhard Meissner
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104338 (2014)
In cardiac muscle, the release of calcium ions from the sarcoplasmic reticulum through ryanodine receptor ion channels (RyR2s) leads to muscle contraction. RyR2 is negatively regulated by calmodulin (CaM) and by phosphorylation of Ca2+/CaM-dependent
Externí odkaz:
https://doaj.org/article/2c7ef560bb6e49e5aa3ee8fb6c33ffea
Autor:
Pasham Parameshwar Reddy, Vijeta Raghuram, Johannes Hradsky, Christina Spilker, Asima Chakraborty, Yogendra Sharma, Marina Mikhaylova, Michael R Kreutz
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103186 (2014)
Caldendrin, L- and S-CaBP1 are CaM-like Ca2+-sensors with different N-termini that arise from alternative splicing of the Caldendrin/CaBP1 gene and that appear to play an important role in neuronal Ca2+-signaling. In this paper we show that Caldendri
Externí odkaz:
https://doaj.org/article/ee03f075b4044c958ce39d3cc4a8f67f
Autor:
Niall Macquaide, L. J Smith, Luis Alberto Gonano, Peter P. Jones, V. Staudacher, C. Thekkedam, A. B. Gamble, Asima Chakraborty, Michelle L. Munro, Angela F. Dulhunty
Publikováno v:
British Journal of Pharmacology. 176:773-786
Background and Purpose: Kinase inhibitors are a common treatment for cancer. Class I kinase inhibitors that target the ATP‐binding pocket are particularly prevalent. Many of these compounds are cardiotoxic and can cause arrhythmias. Spontaneous rel
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1929
Ca
Publikováno v:
Methods in Molecular Biology ISBN: 9781493990290
Ca2+ regulation in living systems occurs via specific structural alterations, subtle or drastic, in the Ca2+-binding domains of sensor proteins. Sensor proteins perform designated nonredundant roles within the dense network of Ca2+-binding proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13fbf20982a120720eded93a33ea8e6b
https://doi.org/10.1007/978-1-4939-9030-6_35
https://doi.org/10.1007/978-1-4939-9030-6_35
Publikováno v:
Biochemistry. 56(19)
A crucial event in calcium signaling is the transition of a calcium sensor from the apo (Ca
Autor:
Angela C. Gomez, Daniel A. Pasek, Naohiro Yamaguchi, Gerhard Meissner, Asima Chakraborty, Le Xu, Tai Qin Huang
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 305:H86-H94
The cardiac ryanodine receptor (RyR2) is inhibited by calmodulin (CaM) and S100A1. Simultaneous substitution of three amino acid residues (W3587A, L3591D, F3603A; RyR2ADA) in the CaM binding domain of RyR2 results in loss of CaM inhibition at submicr
Autor:
Julia Bichler, Michael Kundi, Asima Chakraborty, Karl-Heinz Wagner, Miroslav Mišík, Siegfried Knasmüller, Sandra Sagmeister, Christine Hoelzl, Gerald Haidinger, Tatjana Simic, Walter Jäger, Maria Dusinska, Franziska Ferk, Bettina Grasl-Kraupp, Armen Nersesyan
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 715:61-71
Gallic acid (3,4,5-trihydroxybenzoic acid, GA) is a constituent of plant derived foods, beverages and herbal remedies. We investigated its DNA protective properties in a placebo controlled human intervention trial in single cell gel electrophoresis e
Autor:
Asima Chakraborty, Naohiro Yamaguchi, Gerhard Meissner, Daniel A. Pasek, Jeffery D. Molkentin
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 300:H2187-H2195
Mice with three amino acid mutations in the calmodulin binding domain of type-2 ryanodine receptor ion channel ( Ryr2ADA/ADAmice) have impaired intracellular Ca2+handling and cardiac hypertrophy with death at an early age. In this report, the role of
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 102:161-168
The formation of spatially localized regions of DNA damage by multiphoton absorption of light is an attractive tool for investigating DNA repair. Although this method has been applied in cells, little information is available about the formation of l