Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Asifa Islam"'
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109007- (2024)
Summary: Chromosomal instability (CIN) is a hallmark of cancers, and CIN-promoting mutations are not fully understood. Here, we report 141 chromosomal instability aiding variant (CIVa) candidates by assessing the prevalence of loss-of-function (LoF)
Externí odkaz:
https://doaj.org/article/1e0e32715fda4fc48c04d567eae83dec
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106583- (2023)
Summary: Cell remodeling relies on dynamic rearrangements of cell contacts powered by the actin cytoskeleton. The tumor suppressor adenomatous polyposis coli (APC) nucleate actin filaments (F-actin) and localizes at cell junctions. Whether APC-driven
Externí odkaz:
https://doaj.org/article/c964012c5c854d66b5cfec665369e638
Autor:
Duccio Conti, Parveen Gul, Asifa Islam, José M Martín-Durán, Richard W Pickersgill, Viji M Draviam
Publikováno v:
eLife, Vol 8 (2019)
Microtubules segregate chromosomes by attaching to macromolecular kinetochores. Only microtubule-end attached kinetochores can be pulled apart; how these end-on attachments are selectively recognised and stabilised is not known. Using the kinetochore
Externí odkaz:
https://doaj.org/article/489356cd9c3a4389a1d2ae2eb1ef6539
Figures, main figures and supplemental figures, along codes used in the research project entitled 'APC-driven actin nucleation powers collective cell dynamics in colorectal cancer cells' and submitted as Article for peer-review.
Data, including
Data, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21fad0b5528acaa4827c603b7d5389d3
The vast majority of Chromosomal Instability (CIN) promoting mutations remain unknown. We assess the prevalence of Chromosomal Instability aiding Variants (CIVa) by collating Loss-of-Function (LoF) variants predicted in 135 chromosome segregation gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f0dc4d6712dfc50921a6f6d3c32db62
https://doi.org/10.1101/2022.01.22.477339
https://doi.org/10.1101/2022.01.22.477339
Autor:
Asifa Islam
Publikováno v:
Proceedings of the Microscience Microscopy Congress 2021 incorporating EMAG 2021.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cdfed5d4921c8e79138ce057416a95f
https://doi.org/10.22443/rms.mmc2021.185
https://doi.org/10.22443/rms.mmc2021.185
Publikováno v:
Cytoskeleton-Structure, Dynamics, Function and Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb32176754435610265765c405386d0
https://doi.org/10.5772/intechopen.68321
https://doi.org/10.5772/intechopen.68321