Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Asif J. Iqbal"'
Autor:
Oladimeji Abudu, Duy Nguyen, Isabel Millward, Julia E. Manning, Mussarat Wahid, Abbey Lightfoot, Francesca Marcon, Reena Merard, Sandra Margielewska-Davies, Keith Roberts, Rachel Brown, Sarah Powell-Brett, Samantha M. Nicol, Fouzia Zayou, Wayne D. Croft, Hayden Pearce, Paul Moss, Asif J. Iqbal, Helen M. McGettrick
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116283- (2024)
Background: Galectins (Gal’s) are a family of carbohydrate-binding proteins that are known to support the tumour microenvironment through their immunosuppressive activity and ability to promote metastasis. As such they are attractive therapeutic ta
Externí odkaz:
https://doaj.org/article/c165695e9a5647bc8ea433d32b708818
Autor:
Joshua H. Bourne, Joana Campos, Sophie J. Hopkin, Katharine Whitworth, James Palis, Yotis A. Senis, Julie Rayes, Asif J. Iqbal, Alexander Brill
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome has been described in both immune cells and platelets, but its role in the megakaryocyte (MK) lineage remains elusive.ObjectiveThe aim of this study was to explore t
Externí odkaz:
https://doaj.org/article/f12cd561058a4428b36a02a3bad37820
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Coronary artery disease is among the primary causes of death worldwide. While synthetic grafts allow replacement of diseased tissue, mismatched mechanical properties between graft and native tissue remains a major cause of graft failure. Multi-layere
Externí odkaz:
https://doaj.org/article/22fdd7d277bf4e22a88833b7a3ddd2dc
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Leukocyte recruitment to the site of injury is a crucial event in the regulation of an inflammatory response. Tight regulation of interactions between the endothelium and circulating leukocytes is necessary to ensure a protective response to injury d
Externí odkaz:
https://doaj.org/article/6f2666b534ee4e8abc96542457a22c04
Autor:
Franziska Krautter, Asif J. Iqbal
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Leukocyte recruitment is a highly controlled cascade of interactions between proteins expressed by the endothelium and circulating leukocytes. The involvement of glycans and glycan-binding proteins in the leukocyte recruitment cascade has been well-c
Externí odkaz:
https://doaj.org/article/9af66e84129e4195a96ced9aadae9e24
Autor:
Franziska Krautter, Carlota Recio, Mohammed T. Hussain, Danielle R. Lezama, Francesco Maione, Myriam Chimen, Asif J. Iqbal
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 130, Iss , Pp 110595- (2020)
Macrophages are key cells in both acute and chronic inflammatory settings. Their activation and function highly depends on the cytokines, chemokines and adhesion molecules that direct monocytes to infiltrate tissues, differentiate into macrophages, a
Externí odkaz:
https://doaj.org/article/effe12c5da414ca284fba11a557d1b5c
Autor:
Myriam Chimen, Aigli Evryviadou, Clare L. Box, Matthew J. Harrison, Jon Hazeldine, Lea H. Dib, Sahithi J. Kuravi, Holly Payne, Joshua M.J. Price, Dean Kavanagh, Asif J. Iqbal, Sian Lax, Neena Kalia, Alex Brill, Steve G. Thomas, Antonio Belli, Nicholas Crombie, Rachel A. Adams, Shelley-Ann Evans, Hans Deckmyn, Janet M. Lord, Paul Harrison, Steve P. Watson, Gerard B. Nash, G. Ed Rainger
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Interactions between platelets, leukocytes and the vessel wall provide alternative pathological routes of thrombo-inflammatory leukocyte recruitment. We found that when platelets were activated by a range of agonists in whole blood, they shed platele
Externí odkaz:
https://doaj.org/article/148d3754311e4a4b82c8c3464dde2293
Autor:
Rosa Bellavita, Federica Raucci, Francesco Merlino, Marialuisa Piccolo, Maria Grazia Ferraro, Carlo Irace, Rita Santamaria, Asif J. Iqbal, Ettore Novellino, Paolo Grieco, Nicola Mascolo, Francesco Maione
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 123, Iss , Pp 109788- (2020)
Antimicrobial peptides (AMPs) are an ancient group of defense molecules distributed in nature being found in mammals, birds, amphibians, insects, plants, and microorganisms. They display antimicrobial as well as immunomodulatory properties. The aim o
Externí odkaz:
https://doaj.org/article/b7836a6af04d4f329ad52096ba9beece
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Galectin-1 (Gal-1) exerts immune-regulatory and anti-inflammatory actions in animal models of acute and chronic inflammation. Its release into the extracellular milieu often correlates with the peak of inflammation suggesting that it may serve a pro-
Externí odkaz:
https://doaj.org/article/5e029f0f96ba433091f9e69e74ac4808
Autor:
Federica Raucci, Asif J. Iqbal, Anella Saviano, Gian Marco Casillo, Marina Russo, Danielle Lezama, Nicola Mascolo, Francesco Maione
Publikováno v:
Data in Brief, Vol 25, Iss , Pp - (2019)
The data supplied in this work are related to the research article entitled “IL-17A neutralizing antibody regulates monosodium urate crystal-induced gouty inflammation” [1]. This data article presents the results of the gating strategy applied to
Externí odkaz:
https://doaj.org/article/1d12c75f29ed4bd3854d3fc120d728a5