Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Asier Fullaondo"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2978-2984 (2024)
Short linear motifs (SLiMs) play an important role in protein-protein interactions. However, SLiM patterns are intrinsically permissive and result into many matches that occur just by chance, specially when targeting large datasets. To prioritize the
Externí odkaz:
https://doaj.org/article/e1f5ea287d1040f998c0ee76487714c9
Autor:
Ainize Peña-Cearra, Deguang Song, Janire Castelo, Ainhoa Palacios, Jose Luis Lavín, Mikel Azkargorta, Felix Elortza, Miguel Fuertes, Miguel Angel Pascual-Itoiz, Diego Barriales, Itziar Martín-Ruiz, Asier Fullaondo, Ana M. Aransay, Hector Rodríguez, Noah W. Palm, Juan Anguita, Leticia Abecia
Publikováno v:
npj Biofilms and Microbiomes, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Recent evidence demonstrates potential links between mitochondrial dysfunction and inflammatory bowel diseases (IBD). In addition, bidirectional interactions between the intestinal microbiota and host mitochondria may modulate intestinal inf
Externí odkaz:
https://doaj.org/article/3dff9ee3e3a641b592f1a6aa0abdf433
Autor:
Ainize Peña-Cearra, Janire Castelo, Jose Luis Lavín, Monika Gonzalez-Lopez, Miguel Angel Pascual-Itoiz, Miguel Fuertes, Virginia Gutiérrez de Juan, Laura Bárcena, Itziar Martín-Ruiz, Aize Pellón, Iratxe Seoane, Diego Barriales, Ainhoa Palacios, Asier Fullaondo, Iago Rodríguez-Lago, María L. Martinez-Chantar, Ana Mª Aransay, Hector Rodriguez, Juan Anguita, Leticia Abecia
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTAnti-TNF therapy can induce and maintain a remission status during intestinal bowel disease. However, up to 30% of patients do not respond to this therapy by mechanisms that are unknown. Here, we show that the absence of MCJ, a natural inhibi
Externí odkaz:
https://doaj.org/article/a753bfcd4ae14ccb8c85e30af3536b86
Autor:
Ainize Peña-Cearra, Miguel Angel Pascual-Itoiz, Jose Luis Lavín, Miguel Fuertes, Itziar Martín-Ruiz, Janire Castelo, Ainhoa Palacios, Diego Barriales, Asier Fullaondo, Ana M Aransay, Hector Rodríguez, Juan Anguita, Leticia Abecia
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Inflammatory bowel disease (IBD) is a complex, chronic, relapsing and heterogeneous disease induced by environmental, genomic, microbial and immunological factors. MCJ is a mitochondrial protein that regulates the metabolic status of macroph
Externí odkaz:
https://doaj.org/article/95933cae14fc4f7cbba28c2b763507b1
Autor:
Leire Valcárcel-Ocete, Asier Fullaondo, Gorka Alkorta-Aranburu, María García-Barcina, Raymund A C Roos, Lena E Hjermind, Carsten Saft, Marina Frontali, Ralf Reilmann, Hugh Rickards, REGISTRY investigators of the European Huntington’s Disease Network (EHDN), Ana M Zubiaga, Ana Aguirre
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197975 (2018)
Huntington's disease (HD) age of onset (AO) is mainly determined by the length of the CAG repeat expansion in the huntingtin gene. The remaining AO variability has been attributed to other little-known factors. A factor that has been associated with
Externí odkaz:
https://doaj.org/article/40cbccc9864f42288a97f889c37be2d2
Autor:
Eguzkine Ochoa, Mikel Iriondo, Carmen Manzano, Asier Fullaondo, Irama Villar, Guillermo Ruiz-Irastorza, Ana M Zubiaga, Andone Estonba
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146990 (2016)
The identification of the genetic risk factors that could discriminate non- thrombotic from thrombotic antiphospholipid antibodies (aPLA) carriers will improve prognosis of these patients. Several human studies have shown the presence of aPLAs associ
Externí odkaz:
https://doaj.org/article/896de7fc4dd8410d948139cf0dfe9c75
Autor:
Leire Valcárcel-Ocete, Gorka Alkorta-Aranburu, Mikel Iriondo, Asier Fullaondo, María García-Barcina, José Manuel Fernández-García, Elena Lezcano-García, José María Losada-Domingo, Javier Ruiz-Ojeda, Amaia Álvarez de Arcaya, José María Pérez-Ramos, Raymund A C Roos, Jørgen E Nielsen, Carsten Saft, REGISTRY investigators of the European Huntington's Disease Network, Ana M Zubiaga, Ana Aguirre
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131573 (2015)
Age of onset (AO) of Huntington disease (HD) is mainly determined by the length of the CAG repeat expansion (CAGexp) in exon 1 of the HTT gene. Additional genetic variation has been suggested to contribute to AO, although the mechanism by which it co
Externí odkaz:
https://doaj.org/article/c7ff862050a64eca938de23d82fc92fb
Autor:
Asier Fullaondo Elordui-Zapaterietxe, Ana Mari Zubiaga Elordieta, Alejandro Garcia Aldama, Endika de la Iglesia Menchaca, Jone Mitxelena Sánchez
Publikováno v:
IV. Ikergazte. Nazioarteko ikerketa euskaraz. Kongresuko artikulu bilduma. Zientziak eta Natura Zientzia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d3decf0c2a2e58f73e5d0cd5a528988
https://doi.org/10.26876/ikergazte.iv.05.19
https://doi.org/10.26876/ikergazte.iv.05.19
Autor:
Mónica Álvarez-Fernández, Marcos Malumbres, Aintzane Apraiz, Asier Fullaondo, Ana M. Zubiaga, Jone Mitxelena, Iraia García-Santisteban, Jon Vallejo-Rodríguez
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
instname
Nucleic Acids Research
Repisalud
Instituto de Salud Carlos III (ISCIII)
instname
Nucleic Acids Research
Repisalud
Instituto de Salud Carlos III (ISCIII)
Corrigendum published on 03 July 2019 Nucleic Acids Research 47 (14) : 7716–7717 (2019) https://doi.org/10.1093/nar/gkz587 The cellular response to DNA damage is essential for maintaining the integrity of the genome. Recent evidence has identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a990181ff3c42055f1de4a03b5b6ea98
https://doi.org/10.1093/nar/gky218
https://doi.org/10.1093/nar/gky218
Autor:
Ainhoa Palacios, Rebeca Martín, Aize Pellon, Virginia García-Cañas, Ana Mª Aransay, Rafael Prados-Rosales, Leticia Abecia, Carolina Simó, Ana Carreras-González, Juan Anguita, Estíbaliz Atondo, Héctor Rodríguez, Diego Barriales, Juana M. Flores, Ainize Peña-Cearra, Miguel Angel Pascual-Itoiz, Itziar Martín-Ruiz, Asier Fullaondo, Julen Tomás-Cortázar, José Luis Lavín
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Recent evidences indicate that mitochondrial genes and function are decreased in active ulcerative colitis (UC) patients, in particular, the activity of Complex I of the electron transport chain is heavily compromised. MCJ is a mitochondrial inner me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2568bd2738733ba2a0a6074211e963a8
https://pubmed.ncbi.nlm.nih.gov/31953445
https://pubmed.ncbi.nlm.nih.gov/31953445