Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Asier, Ruiz"'
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S238- (2023)
Externí odkaz:
https://doaj.org/article/4fedeb50413741408fe57791490f1260
Autor:
Blanca Isabel Ochoa-Bueno, Laura Bayón-Cordero, Nuria Galbis-Gramage, Asier Ruiz, Elena Alberdi, María Victoria Sánchez-Gómez
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S464- (2023)
Externí odkaz:
https://doaj.org/article/a4dbf8183ebf454abab37d0e6fda61ec
Autor:
Uxue Balantzategi, Adhara Gaminde-Blasco, Lierni Aizpurua, Juanma Ramírez, Ugo Mayor, Asier Ruiz, Carlos Matute, José Luis Zugaza, Elena Alberdi
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S364- (2023)
Externí odkaz:
https://doaj.org/article/e298065dcca948c5977a904a3edc8d46
Autor:
Carolina Ortiz-Sanz, Uxue Balantzategi, Tania Quintela-López, Asier Ruiz, Celia Luchena, Jone Zuazo-Ibarra, Estibaliz Capetillo-Zarate, Carlos Matute, José L. Zugaza, Elena Alberdi
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-12 (2022)
Abstract Amyloid beta (Aβ)-mediated synapse dysfunction is an early event in Alzheimer’s disease (AD) pathogenesis and previous studies suggest that NMDA receptor (NMDAR) dysregulation may contribute to these pathological effects. Although Aβ pep
Externí odkaz:
https://doaj.org/article/b3b6362fac3d49c5854d28bbf5043e89
Autor:
Laura Bayón-Cordero, Blanca Isabel Ochoa-Bueno, Asier Ruiz, Marina Ozalla, Carlos Matute, María Victoria Sánchez-Gómez
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Oligodendrocytes are the myelin forming cells of the central nervous system, and their vulnerability to excitotoxicity induced by glutamate contributes to the pathogenesis of neurological disorders including brain ischemia and neurodegenerative disea
Externí odkaz:
https://doaj.org/article/003888555b674353a4e682d6f9103751
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6088 (2020)
Sephin1 is a derivative of guanabenz that inhibits the dephosphorylation of the eukaryotic initiation factor 2 alpha (eIF2α) and therefore may enhance the integrated stress response (ISR), an adaptive mechanism against different cellular stresses, s
Externí odkaz:
https://doaj.org/article/d12e48e4ec2b4e93942f9f90494b025a
Autor:
Manuel Canedo-Antelo, Mari Paz Serrano, Andrea Manterola, Asier Ruiz, Francisco Llavero, Susana Mato, José Luis Zugaza, Fernando Pérez-Cerdá, Carlos Matute, María Victoria Sánchez-Gómez
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Oligodendrocytes are highly vulnerable to glutamate excitotoxicity, a central mechanism involved in tissue damage in Multiple Sclerosis (MS). Sustained activation of AMPA receptors in rat oligodendrocytes induces cytosolic calcium overload, mitochond
Externí odkaz:
https://doaj.org/article/c89429a52d854e3aba2f9107b1259128
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Excessive dynamin related protein 1 (Drp1)-triggered mitochondrial fission contributes to apoptosis under pathological conditions and therefore it has emerged as a promising therapeutic target. Mitochondrial division inhibitor 1 (mdivi-1) inhibits Dr
Externí odkaz:
https://doaj.org/article/ad88b48ff8cb4c9cbd434aac7c17bfe8
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
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Microglia act as sensors of injury in the brain, favouring its homeostasis. Their activation and polarization towards a pro-inflammatory phenotype are associated to injury and disease. These processes are linked to a metabolic reprogramming of the ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f0703432beb4db8444dbd1a9e5f698
https://doi.org/10.4049/immunohorizons.2100068
https://doi.org/10.4049/immunohorizons.2100068
Publikováno v:
Drug and Chemical Toxicology. 45:1634-1643
Styrene 7,8-oxide (SO) is the principal metabolite of styrene, an industrial neurotoxic compound which causes various neurodegenerative disorders. The present study aimed to explore the mechanisms ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fe9c04c4ab8af51891427f9682d25b6
https://doi.org/10.1080/01480545.2020.1851706
https://doi.org/10.1080/01480545.2020.1851706