Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ashworth, Roxann"'
Autor:
Mathias, Rasika A., Grant, Audrey V., Rafaels, Nicholas, Hand, Tracey, Gao, Li, Vergara, Candelaria, Tsai, Yuhjung J., Yang, Mao, Campbell, Monica, Foster, Cassandra, Gao, Peisong, Togias, A., Hansel, Nadia N., Diette, Gregory, Adkinson, N. Franklin, Liu, Mark C., Faruque, Mezbah, Dunston, Georgia M., Watson, Harold R., Bracken, Michael B., Hoh, Josephine, Maul, Pissamai, Maul, Trevor, Jedlicka, Anne E., Murray, Tanda, Hetmanski, Jacqueline B., Ashworth, Roxann, Ongaco, Chrissie M., Hetrick, Kurt N., Doheny, Kimberly F., Pugh, Elizabeth W., Rotimi, Charles N., Ford, Jean, Eng, Celeste, Burchard, Esteban G., Sleiman, Patrick M.A., Hakonarson, Hakon, Forno, Erick, Raby, Benjamin A., Weiss, Scott T., Scott, Alan F., Kabesch, Michael, Liang, Liming, Abecasis, Gonçalo, Moffatt, Miriam F., Cookson, William O.C., Ruczinski, Ingo, Beaty, Terri H., Barnes, Kathleen C.
Publikováno v:
In The Journal of Allergy and Clinical Immunology 2010 125(2):336-346
Publikováno v:
J Biomol Tech
FFPE tissue is the standard by which biopsied tissue is preserved for molecular analyses, such as NGS. However, current methods to purify nucleic acid from FFPE are technically challenging, often limiting both the yield and quality obtained. We descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::2b431d771c0a90a58f0541ca12edde2c
https://europepmc.org/articles/PMC7424779/
https://europepmc.org/articles/PMC7424779/
Publikováno v:
J Biomol Tech
Cell-free DNA (cfDNA) has become an important source for potential new biomarkers. Via liquid biopsies it is easily accessible and can be a non-invasive way for genetic information. Nevertheless, it represents a challenging sample type due to its low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::1b4bebb7e6e342334839b138c731f167
https://europepmc.org/articles/PMC7425020/
https://europepmc.org/articles/PMC7425020/
Autor:
Brown, Keith, Siddique, Azeem, Suckow, Gaia, Homer, Nils, Carey, Jay, Ordoukhanian, Phillip, Head, Steve, Pickrell, Joseph, Kim, Ryan, Ashworth, Roxann, Chittur, Sridar, Kermack, Justin
Publikováno v:
J Biomol Tech
In this study, 384 genomic DNA samples were prepared as multiplex sequencing libraries using the Riptide™ high throughput library preparation kit and sequenced on four lanes of a Novaseq S4 flow cell with 2x 150 PE reads (96 samples per lane). Samp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_dedup___::4b65f095206419ffcb9ff5396c31a6aa
https://europepmc.org/articles/PMC7424768/
https://europepmc.org/articles/PMC7424768/
Autor:
Eimerman, Patrick, Jeddeloh, Jeffrey, Champion, Elise, Peponnet, Christine, Gariel, Sylvain, Godron, Xavier, Ybert, Thomas, Ashworth, Roxann, Knudtson, Kevin
Publikováno v:
J Biomol Tech
Our novel, enzymatic DNA synthesis (EDS) technology was made through engineering of three critical components: a DNA polymerase, a solid support, and reversible terminators. Terminal deoxynucleotidyl-Transferase (TdT), which performs poly-nucleotide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::52d94d4814d38c52b52b06df6c185692
https://europepmc.org/articles/PMC7424958/
https://europepmc.org/articles/PMC7424958/
Autor:
Siwicki, Rebecca, Madaj, Zachary, Pettinga, Dean, Wegener, Marc, Ellis, Abigail, Isaguirre, Christine, DeCamp, Lisa, Rohrer, Dan, Kirchoff, Megan, Jones, Russell, Givan, Scott, Jewell, Scott, Sheldon, Ryan, Adams, Marie, Ashworth, Roxann, Knudtson, Kevin
Publikováno v:
J Biomol Tech
Availability of biological material is often a limiting factor in generating robust, multi-omics datasets. Additionally, regional tissue heterogeneity obscures the ability to directly compare adjacent regions. This is particularly true of mass-spectr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::b827ee07bf03d6abb78a4b7ff990e69e
https://europepmc.org/articles/PMC7424967/
https://europepmc.org/articles/PMC7424967/
Autor:
Gandlur, Suvarna, Fish, Rachel, Young, Michael, Liu, Lyndon, Wei, Sherry, Swaminathan, Karthikeyan, Bostick, Magnolia, Farmer, Andrew, Ashworth, Roxann, Knudtson, Kevin
Publikováno v:
J Biomol Tech
Isolating single cells at high-throughput levels and obtaining their full-length transcript information has become critical to the scientific community to generate rich single-cell datasets. We automated SMART-Seq® chemistry on the ICELL8® cx Singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::166f55ae762c579457d11ca88f800c4c
https://europepmc.org/articles/PMC7424911/
https://europepmc.org/articles/PMC7424911/
Autor:
Siddique, Azeem, Brown, Keith, Suckow, Gaia, Homer, Nils, Ordoukhanian, Phillip, Head, Steve, Pickrell, Joseph, Kim, Ryan, Ashworth, Roxann, Chittur, Sridar, Kermack, Justin
Publikováno v:
J Biomol Tech
Over the past two decades, large population genotyping studies have delivered a better understanding of disease, an expanded pipeline of therapeutic targets and new diagnostic/predictive tests to improve health and wellness. Today's most comprehensiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::e864ebffc2c470980014fb92a5c13bc4
https://europepmc.org/articles/PMC7424969/
https://europepmc.org/articles/PMC7424969/
Autor:
Wegener, Marc, Rhodes, Mary, Johnson, Benjamin, Sheridan, Rachael, Himadewi, Pamela, Foy, Kelly, Shen, Hui, Triche, Timothy, Adams, Marie, Ashworth, Roxann, Chittur, Sridar
Publikováno v:
J Biomol Tech
Miniaturization of library preparation methods has been shown to significantly decrease both costs and labor associated with next generation DNA sequencing, without sacrificing the quality of data obtained. By reducing reaction volumes, the number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::967d9be09f3617fbbf8c6fa12349bfdb
https://europepmc.org/articles/PMC7424903/
https://europepmc.org/articles/PMC7424903/
Autor:
Ravanelli, Andrew, Meer, Elliott, Terry, Jessica, Ji, Qingzhou, Ashworth, Roxann, Chittur, Sridar
Publikováno v:
J Biomol Tech
The power of CRISPR-Cas9 for genome engineering has continued to grow in recent years. The ability to perform large-scale, whole genome loss-of-function screens has allowed for new breakthroughs identifying gene pathways in drug resistance and diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::4e60b149aeca9e806816af3a8a73aa84
https://europepmc.org/articles/PMC7424921/
https://europepmc.org/articles/PMC7424921/