Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ashwinkumar, Bhirde"'
Autor:
Minkyung Kim, Youlong Ma, Charudharshini Srinivasan, Thomas O’Connor, Srivalli N. Telikepalli, Dean C. Ripple, Scott Lute, Ashwinkumar Bhirde
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Subvisible particles (SVPs) are a critical quality attribute of injectable therapeutic proteins (TPs) that needs to be controlled due to potential risks associated with drug product quality. The current compendial methods routinely used to a
Externí odkaz:
https://doaj.org/article/59fedfcc14744d30b6b9e3712346a229
Autor:
Srivalli N, Telikepalli, Michael J, Carrier, Dean C, Ripple, Greg, Barnett, Ashwinkumar, Bhirde, Donna, Bolton, George M, Bou-Assaf, Erica, Ferrari, Scott, Leigh, Sophia, Levitskaya-Seaman, Tim, Menzen, Felix, Nikels, Anna, Riley, Miguel, Saggu, Neha, Sahni, Eric, Vernooij, Klaus, Wuchner
Publikováno v:
AAPS PharmSciTech. 24
Visible protein-like particle standards may improve visual inspection and/or appearance testing practices used in the biotechnology industry. They may improve assay performance resulting in better alignment and more standardized training among differ
Autor:
Minkyung Kim, Bhaskara Vijaya Chikkaveeraiah, Drishti Maniar, Brian Roelofs, Muthukumar Ramaswamy, Gopal Abbineni, Cyrus Agarabi, Ashwinkumar Bhirde
Publikováno v:
Journal of pharmaceutical sciences. 111(9)
Fast-acting insulin drug products (DPs) are carried and administered by diabetic patients to maintain their blood glucose level throughout the day, exposing the DPs to stress conditions. Apidra, Novolog, and Humalog insulin DPs were tested under vari
Publikováno v:
Theranostics, Vol 1, Iss 1, Pp 274-276 (2011)
This commentary highlights the findings by Kessinger et al. (Theranostics 2011; 1: 263-275) that dynamic T2*-weighted magnetic resonance imaging (MRI) of cyclic RGD peptide-encoded superparamagnetic polymeric micelle (SPPM) nanoparticles allows quant
Externí odkaz:
https://doaj.org/article/840956f6ffe44274a534978371eb127e
Autor:
Angela R. Hight Walker, Ankur Kapoor, Zhe Wang, Avinash Srivatsan, Richard D. Leapman, Xiaoyuan Chen, J. Silvio Gutkind, Sachin Patel, Gang Niu, Bhaskara V. Chikkaveeraiah, Alexander M. Gorbach, Albert J. Jin, Vyomesh Patel, Ashwinkumar Bhirde
Publikováno v:
ACS Nano
Resistance to chemotherapy is the primary cause of treatment failure in over 90% of cancer patients in the clinic. Research in nanotechnology-based therapeutic alternatives has helped provide innovative and promising strategies to overcome multidrug
Autor:
Ashwinkumar Bhirde, Xinglu Huang, Gang Liu, Xiaoyuan Chen, Jianbo Cao, Xiaoyong Wang, Ya-Ping Sun, Yun Zeng, Liqin Wang
Publikováno v:
Advanced Healthcare Materials. 3:1203-1209
The emergence of photoluminescent carbon-based nanomaterials offers great potential for a wide variety of biomedical applications such as fluorescence imaging and cellular labeling. This report illustrates a novel photonic carbon dot (Cdots) based na
Autor:
Zhuang Liu, Wei Wang, Zhe Wang, Dale O. Kiesewetter, Avinash Srivastan, Pengfei Rong, Fu Wang, Xiaoyuan Chen, Xuyi Yue, Gang Niu, Kai Yang, Liming Nie, Ashwinkumar Bhirde
Publikováno v:
Theranostics
Graphene, a 2-dimensional carbon nanomaterial, has attracted wide attention in biomedical applications, owing to its intrinsic physical and chemical properties. In this work, a photosensitizer molecule, 2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-
Autor:
Xiaolian Sun, Ashwinkumar Bhirde, Xiaoyuan Chen, Shouju Wang, Ruijun Xing, Gang Liu, Yanglong Hou
Publikováno v:
Nano Research. 6:1-9
National Basic Research Program of China (973 Program) [2013CB733802, 2010CB934602]; National Science Foundation of China (NSFC) [81101101, 81201086, 81201129, 81201190, 51273165, 51172005, 81028009]; Chinese Academy of Sciences Professorship for Sen
Highly Robust, Recyclable Displacement Assay for Mercuric Ions in Aqueous Solutions and Living Cells
Autor:
Xingyu Jiang, Shouju Wang, Min Yang, Jiashu Sun, Dingbin Liu, Ashwinkumar Bhirde, Zhuo Wang, Xinglu Huang, Xiaoyuan Chen, Magdalena Swierczewska
Publikováno v:
ACS Nano. 6:10999-11008
We designed a recyclable Hg(2+) probe based on Rhodamine B isothiocyanate (RBITC)-poly(ethylene glycol) (PEG)-comodified gold nanoparticles (AuNPs) with excellent robustness, selectivity, and sensitivity. On the basis of a rational design, only Hg(2+
Autor:
J. Silvio Gutkind, Richard D. Leapman, Ramiro Iglesias-Bartolome, Ashwinkumar Bhirde, Seulki Lee, Xiaoyuan Chen, Albert J. Jin, Ankur Kapoor, Gang Liu, Guofeng Zhang, Ruijun Xing
Publikováno v:
ACS Nano. 6:4966-4972
Nanoformulations have shown great promise for delivering chemotherapeutics and hold tremendous clinical relevance. However nuclear mapping of the chemo drugs is important to predict the success of the nanoformulation. Herein in this study fluorescenc