Zobrazeno 1 - 10
of 377
pro vyhledávání: '"Ashwini Nangia"'
Autor:
Geetha Bolla, Ashwini Nangia
Publikováno v:
IUCrJ, Vol 6, Iss 4, Pp 751-760 (2019)
Sulfonamide drugs are well known antibacterial and antimicrobial molecules for pharmaceutical development. Building a library of suitable supramolecular synthons for the sulfonamide functional group and understanding their crystal structures with par
Externí odkaz:
https://doaj.org/article/601fafac99fd4256ba06c72b78ef0f2a
Publikováno v:
IUCrJ, Vol 5, Iss 6, Pp 816-822 (2018)
The single-crystal X-ray structure of a 6-component organic-salt alloy (hexanary) of naftopidil (1) (an active pharmaceutical ingredient) with benzoic acid (2) and four different hydroxy-substituted benzoic acids, i.e. salicylic acid (3), 2,3-dihydro
Externí odkaz:
https://doaj.org/article/3bd1b672b6e84b24a28f5c618af17d6f
Publikováno v:
IUCrJ, Vol 4, Iss 6, Pp 812-823 (2017)
The design and synthesis of mechanically responsive materials is interesting because they are potential candidates to convert thermal energy into mechanical work. Reported in this paper are thermosalient effects in a series of halogen derivatives of
Externí odkaz:
https://doaj.org/article/7d1ae4555f2545f3b3e1090024835bf4
Publikováno v:
IUCrJ, Vol 4, Iss 3, Pp 243-250 (2017)
Polymorphs of the dichloro derivative of N-salicylideneaniline exhibit mechanical responses such as jumping (Forms I and III) and exploding (Form II) in its three polymorphs. The molecules are connected via the amide N—H...O dimer synthon and C—C
Externí odkaz:
https://doaj.org/article/0e458d237e38437c839f8f2d908fb4ec
Publikováno v:
IUCrJ, Vol 4, Iss 3, Pp 206-214 (2017)
Cocrystals of acemetacin drug (ACM) with nicotinamide (NAM), p-aminobenzoic acid (PABA), valerolactam (VLM) and 2-pyridone (2HP) were prepared by melt crystallization and their X-ray crystal structures determined by high-resolution powder X-ray diffr
Externí odkaz:
https://doaj.org/article/4e9cef7cfe6043139457b38b8671a27e
Autor:
Geetha Bolla, Ashwini Nangia
Publikováno v:
IUCrJ, Vol 3, Iss 2, Pp 152-160 (2016)
A novel design strategy for cocrystals of a sulfonamide drug with pyridine carboxamides and cyclic amides is developed based on synthon identification as well as size and shape match of coformers. Binary adducts of acetazolamide (ACZ) with lactams (v
Externí odkaz:
https://doaj.org/article/5ef308044f734326b0975c3b48e74113
Publikováno v:
IUCrJ, Vol 6, Iss 5, Pp 786-787 (2019)
Externí odkaz:
https://doaj.org/article/d3be8d658f214bf183e445daa08f0296
Modularity and three-dimensional isostructurality of novel synthons in sulfonamide–lactam cocrystals
Publikováno v:
IUCrJ, Vol 2, Iss 4, Pp 389-401 (2015)
The design of novel supramolecular synthons for functional groups relevant to drugs is an essential prerequisite for applying crystal engineering in the development of novel pharmaceutical cocrystals. It has been convincingly shown over the past deca
Externí odkaz:
https://doaj.org/article/897376b535ef4c359969e22fef2e51fd
Publikováno v:
IUCrJ, Vol 1, Iss 2, Pp 136-150 (2014)
Acemetacin (ACM) is a non-steroidal anti-inflammatory drug (NSAID), which causes reduced gastric damage compared with indomethacin. However, acemetacin has a tendency to form a less soluble hydrate in the aqueous medium. We noted difficulties in the
Externí odkaz:
https://doaj.org/article/5047b7733b3a41cd9ed81870d255dd44
Autor:
M. K. Chaitanya Mannava, Kuthuru Suresh, Manish Kumar Bommaka, Durga Bhavani Konga, Ashwini Nangia
Publikováno v:
Pharmaceutics, Vol 10, Iss 1, p 7 (2018)
Curcumin is a natural compound present in Indian spice turmeric. It has diverse pharmacological action but low oral solubility and bioavailability continue to limit its use as a drug. With the aim of improving the bioavailability of Curcumin (CUR), w
Externí odkaz:
https://doaj.org/article/fc2b4dd080a34300adc976ff799264ca