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pro vyhledávání: '"Ashwin Uttam"'
Autor:
Hsiaoyin Mao, Mario Notari, Ashwin Uttam, Rebecca Bruner-Klisovic, Shujun Liu, Clara D. Bloomfield, Mauro Valtieri, Michael A. Caligiuri, Danilo Perrotti, Rossana Trotta, Ji Suk Chang, Denis C. Roy, Ramasamy Santhanam, Bradley W. Blaser, Paolo Neviani, Annamaria Galietta, Guido Marcucci
Publikováno v:
Cancer Cell. 8:355-368
SummaryThe oncogenic BCR/ABL kinase activity induces and maintains chronic myelogenous leukemia (CML). We show here that, in BCR/ABL-transformed cells and CML blast crisis (CML-BC) progenitors, the phosphatase activity of the tumor suppressor PP2A is
Publikováno v:
Developmental Biology. 262(1):88-93
Developmental pattern formation allows cells within a tissue or organ to coordinate their development and establish cell types in relationship to one another. To better characterize the developmental patterning events within one organ, the C. elegans