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Akademický článek

Exploring the relative water scarcity across the Indian million-plus urban agglomerations: An application of the Water Poverty Index

Autor: Aparna Sivaraman Prabha, Ashwin Ram, Zareena Begum Irfan

Publikováno v: HydroResearch, Vol 3, Iss , Pp 134-145 (2020)

Indian cities are rapidly expanding and with increase in migration the country is expected to witness unprecedented urbanization in the coming decade. In this context, it is important to take a holistic and realistic view of the challenges faced by I

Externí odkaz: https://doaj.org/article/d28a342b601c4b8bb2226cdd6d57d987

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Supplementary Figure 4 from Cotargeting MAPK and PI3K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer

Autor: Judith Sebolt-Leopold, Alnawaz Rehemtulla, Theodore S. Lawrence, Brian D. Ross, Craig J. Galbán, Stefanie Galbán, David Karnak, Ashwin Ram, Paul Keller, Athena R. Flecha, Terence M. Williams

PDF file, 332KB, Immunoblotting for cleaved PARP 24 hours after radiation treatment, PD0325901, and API-2 treatment to detect activation of apoptotic pathways.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b4ca5413ad1dd1119493f5dcf452a3
https://doi.org/10.1158/1535-7163.22497604.v1

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Supplementary Figure 2 from Cotargeting MAPK and PI3K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer

Autor: Judith Sebolt-Leopold, Alnawaz Rehemtulla, Theodore S. Lawrence, Brian D. Ross, Craig J. Galbán, Stefanie Galbán, David Karnak, Ashwin Ram, Paul Keller, Athena R. Flecha, Terence M. Williams

PDF file, 41KB, Changes in weight during the study period for the mice randomized to the eight treatment groups described.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3846abdebb37d10ac4b6edb13399ed
https://doi.org/10.1158/1535-7163.22497610

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Supplementary Figure 5 from Cotargeting MAPK and PI3K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer

Autor: Judith Sebolt-Leopold, Alnawaz Rehemtulla, Theodore S. Lawrence, Brian D. Ross, Craig J. Galbán, Stefanie Galbán, David Karnak, Ashwin Ram, Paul Keller, Athena R. Flecha, Terence M. Williams

PDF file, 48KB, Changes in MRI tumor volume for mice treated with radiation alone, API-2, or radiation with API-2. There was no radiosensitization observed with API-2 in the absence of a MEK inhibitor.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c400f77d459c33e1f7467bef001d3be
https://doi.org/10.1158/1535-7163.22497598.v1

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Supplementary Figure 3 from Cotargeting MAPK and PI3K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer

Autor: Judith Sebolt-Leopold, Alnawaz Rehemtulla, Theodore S. Lawrence, Brian D. Ross, Craig J. Galbán, Stefanie Galbán, David Karnak, Ashwin Ram, Paul Keller, Athena R. Flecha, Terence M. Williams

PDF file, 327KB, Treatment of MIA-PaCa-2 cells with API-2 induces potent inhibition of Akt activation at 1 hour, regardless of the presence of PD0325901.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0072a68526c75955735ec102d2965437
https://doi.org/10.1158/1535-7163.22497607.v1

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Supplementary Figure 1 from Cotargeting MAPK and PI3K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer

Autor: Judith Sebolt-Leopold, Alnawaz Rehemtulla, Theodore S. Lawrence, Brian D. Ross, Craig J. Galbán, Stefanie Galbán, David Karnak, Ashwin Ram, Paul Keller, Athena R. Flecha, Terence M. Williams

PDF file, 318KB, Dose dependency of PD0325901 in multiple cell lines. Treatment with PD0325901 induces potent inhibition of pERK-1/2 levels at one and three hours.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df4c8c4a876d89e13fc7c594368c5c1
https://doi.org/10.1158/1535-7163.22497613

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Supplementary Figure Legend from Cotargeting MAPK and PI3K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer

Autor: Judith Sebolt-Leopold, Alnawaz Rehemtulla, Theodore S. Lawrence, Brian D. Ross, Craig J. Galbán, Stefanie Galbán, David Karnak, Ashwin Ram, Paul Keller, Athena R. Flecha, Terence M. Williams

PDF file, 44KB.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115c5899bb76fc459dfb59b2bb94b548
https://doi.org/10.1158/1535-7163.22497595

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Data from Cotargeting MAPK and PI3K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer

Autor: Judith Sebolt-Leopold, Alnawaz Rehemtulla, Theodore S. Lawrence, Brian D. Ross, Craig J. Galbán, Stefanie Galbán, David Karnak, Ashwin Ram, Paul Keller, Athena R. Flecha, Terence M. Williams

There is an urgent need for the development of novel therapies to treat pancreatic cancer, which is among the most lethal of all cancers. KRAS-activating mutations, which are found in more than 90% of pancreatic adenocarcinomas, drive tumor dependenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7662108ee8bc8d7b049f3bb943642e
https://doi.org/10.1158/1535-7163.c.6535666

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Stochastic Plan Optimization in Real-Time Strategy Games

Autor: Andrew Trusty, Santiago Santiago Ontañón, Ashwin Ram

Publikováno v: Proceedings of the AAAI Conference on Artificial Intelligence and Interactive Digital Entertainment. 4:126-131

We present a domain independent off-line adaptation technique called Stochastic Plan Optimization for finding and improving plans in real-time strategy games. Our method is based on ideas from genetic algorithms but we utilize a different representat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7dcc6621a98c7d0ed48d980c22a2d0c4
https://doi.org/10.1609/aiide.v4i1.18684

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An Intelligent IDE for Behavior Authoring in Real-Time Strategy Games

Autor: Suhas Virmani, Yatin Kanetkar, Manish Mehta, Santiago Ontañón, Ashwin Ram

Publikováno v: Proceedings of the AAAI Conference on Artificial Intelligence and Interactive Digital Entertainment. 4:209-214

Behavior authoring for computer games involves writing behaviors in a programming language and then iteratively refining them by detecting issues with them. The main bottlenecks are a) the effort required to author the behaviors and b) the revision c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::88e1f0535246e20e3ce86dcc2ebcd9ba
https://doi.org/10.1609/aiide.v4i1.18699

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