Výsledky vyhledávání - "Ashwin Muruhadas"

Supplementary Figure Legends 1-3 from CYP2S1 and CYP2W1 Mediate 2-(3,4-Dimethoxyphenyl)-5-Fluorobenzothiazole (GW-610, NSC 721648) Sensitivity in Breast and Colorectal Cancer Cells

Autor: Chee-Onn Leong, Malcolm F.G. Stevens, Tracey D. Bradshaw, Heng Lungh Choo, Nirmal Randhawa, Ashwin Muruhadas, Kai Hung Tiong, Boon Shing Tan

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c0e9465ad4a531af2ba888341fb366
https://doi.org/10.1158/1535-7163.22496415.v1

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Supplementary Figures 1-3 from CYP2S1 and CYP2W1 Mediate 2-(3,4-Dimethoxyphenyl)-5-Fluorobenzothiazole (GW-610, NSC 721648) Sensitivity in Breast and Colorectal Cancer Cells

Autor: Chee-Onn Leong, Malcolm F.G. Stevens, Tracey D. Bradshaw, Heng Lungh Choo, Nirmal Randhawa, Ashwin Muruhadas, Kai Hung Tiong, Boon Shing Tan

PDF file - 569K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74a6bf280570d8fd314b8501dcde481
https://doi.org/10.1158/1535-7163.22496412

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Data from CYP2S1 and CYP2W1 Mediate 2-(3,4-Dimethoxyphenyl)-5-Fluorobenzothiazole (GW-610, NSC 721648) Sensitivity in Breast and Colorectal Cancer Cells

Autor: Chee-Onn Leong, Malcolm F.G. Stevens, Tracey D. Bradshaw, Heng Lungh Choo, Nirmal Randhawa, Ashwin Muruhadas, Kai Hung Tiong, Boon Shing Tan

Both 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F-203; NSC 703786) and 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW-610; NSC 721648) are antitumor agents with novel mechanism(s). Previous studies have indicated that cytochrome (CYP) P450

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d3d3106604927bfb2cf8eff32dc1c6
https://doi.org/10.1158/1535-7163.c.6535263.v1

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Supplementary Table 1 from CYP2S1 and CYP2W1 Mediate 2-(3,4-Dimethoxyphenyl)-5-Fluorobenzothiazole (GW-610, NSC 721648) Sensitivity in Breast and Colorectal Cancer Cells

Autor: Chee-Onn Leong, Malcolm F.G. Stevens, Tracey D. Bradshaw, Heng Lungh Choo, Nirmal Randhawa, Ashwin Muruhadas, Kai Hung Tiong, Boon Shing Tan

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::500294b0165133573b96dfd839e8e6b5
https://doi.org/10.1158/1535-7163.22496409.v1

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CYP2S1 and CYP2W1 Mediate 2-(3,4-Dimethoxyphenyl)-5-Fluorobenzothiazole (GW-610, NSC 721648) Sensitivity in Breast and Colorectal Cancer Cells

Autor: Nirmal Randhawa, Chee-Onn Leong, Ashwin Muruhadas, Tracey D. Bradshaw, Heng Lungh Choo, Malcolm F. G. Stevens, Boon Shing Tan, Kai Hung Tiong

Publikováno v: Molecular Cancer Therapeutics. 10:1982-1992

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0e09ddfe05541b6c89452f7cd4a514
https://doi.org/10.1158/1535-7163.mct-11-0391

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Abstract C75: CYP2S1 and CYP2W1 mediate 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW610, NSC 721648) sensitivity in breast and colorectal cancer cells

Autor: Chee-Onn Leong, Boon Shing Tan, Kai Hung Tiong, Ashwin Muruhadas, Nirmal Randhawa, Heng Lungh Choo, Malcolm FG Stevens, Tracey D. Bradshaw

Publikováno v: Molecular Cancer Therapeutics. 10:C75-C75

Phortress, the lysylamide prodrug of 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F203, NSC 703786) is under clinical evaluation. CYP1A1-catalyzed bioactivation of 5F203 is crucial for antitumor activity. 2-(3,4-Dimethoxyphenyl)-5-fluorobenzoth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3035cbe3de0f71f306e60e3c6ce4638
https://doi.org/10.1158/1535-7163.targ-11-c75

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