Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ashwathi P Menon"'
Autor:
Lei Huang, Ramireddy Bommireddy, Luis E Munoz, Rohini N Guin, Changyong Wei, Amanda Ruggieri, Ashwathi P Menon, Xiaoxian Li, Mala Shanmugam, Taofeek K Owonikoko, Suresh S Ramalingam, Periasamy Selvaraj
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0254125 (2021)
Imaging techniques based on fluorescence and bioluminescence have been important tools in visualizing tumor progression and studying the effect of drugs and immunotherapies on tumor immune microenvironment in animal models of cancer. However, transge
Externí odkaz:
https://doaj.org/article/dc6e930ff2a44d15a2ac8e0dd7a119d8
Autor:
Mario M Soldevilla, Helena Villanueva, Naiara Martinez-Velez, Daniel Meraviglia-Crivelli, Marta M Alonso, Javier Cebollero, Ashwathi P Menon, Montserrat Puigdelloses, Fernando Pastor
Publikováno v:
OncoImmunology, Vol 7, Iss 8 (2018)
In spite of the success of PD-1 blocking antibodies in the clinic their benefits are still restricted to a small fraction of patients. Immune-desert tumors and/or the highly immunosuppressive tumor milieu might hamper the success of PD-1/PD-L1 blocki
Externí odkaz:
https://doaj.org/article/a00e6e238c7a4f1aa23b2515f56475ec
Autor:
Ashwathi Puravankara Menon, Helena Villanueva, Daniel Meraviglia-Crivelli, Hisse M. van Santen, Joschka Hellmeier, Angelina Zheleva, Francesca Nonateli, Timo Peters, Tassilo L.A. Wachsmann, Mercedes Hernandez-Rueda, Johannes B. Huppa, Gerhard J. Schütz, Eva Sevcsik, Beatriz Moreno, Fernando Pastor
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102198- (2024)
The CD3/T cell receptor (TCR) complex is responsible for antigen-specific pathogen recognition by T cells, and initiates the signaling cascade necessary for activation of effector functions. CD3 agonistic antibodies are commonly used to expand T lymp
Externí odkaz:
https://doaj.org/article/6c3ef753dfa94901b0ef2480454cb96e
Autor:
Daniel Meraviglia-Crivelli, Helena Villanueva, Angelina Zheleva, María Villalba-Esparza, Beatriz Moreno, Ashwathi Puravankara Menon, Alfonso Calvo, Javier Cebollero, Martin Barainka, Igor Ruiz de los Mozos, Carlos Huesa-Berral, Fernando Pastor
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-24 (2022)
Abstract Background The quality and quantity of tumor neoantigens derived from tumor mutations determines the fate of the immune response in cancer. Frameshift mutations elicit better tumor neoantigens, especially when they are not targeted by nonsen
Externí odkaz:
https://doaj.org/article/2e8fa14d44924374b4eb660bb5319ae9
Autor:
Daniel Meraviglia-Crivelli, Helena Villanueva, Ashwathi Puravankara Menon, Angelina Zheleva, Beatriz Moreno, María Villalba-Esparza, Fernando Pastor
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 413-425 (2022)
Immune-checkpoint blockade (ICB) therapy has changed the clinical outcome of many types of aggressive tumors, but there still remain many cancer patients that do not respond to these treatments. There is an unmet need to develop a feasible clinical t
Externí odkaz:
https://doaj.org/article/12638e60bd4c449d8adab68bb1e7c48d
Publikováno v:
Pharmaceuticals, Vol 11, Iss 4, p 108 (2018)
Aptamers are single-stranded oligonucleotides (ssDNA or ssRNA) that bind and recognize their targets with high affinity and specificity due to their complex tertiary structure. Aptamers are selected by a method called SELEX (Systematic Evolution of L
Externí odkaz:
https://doaj.org/article/cc3bb26d66534cb89850d13cfcc7dbe5
Autor:
Xiaoxian Li, Ashwathi P. Menon, Mala Shanmugam, Suresh S. Ramalingam, Taofeek K. Owonikoko, Lei Huang, Ramireddy Bommireddy, Periasamy Selvaraj, Rohini N. Guin, Amanda Ruggieri, Changyong Wei, Luis E. Munoz
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0254125 (2021)
PLoS ONE
PLoS ONE
Imaging techniques based on fluorescence and bioluminescence have been important tools in visualizing tumor progression and studying the effect of drugs and immunotherapies on tumor immune microenvironment in animal models of cancer. However, transge
Autor:
Ramireddy Bommireddy, Haley Lei Huang, Ashwathi P. Menon, Periasamy Selvaraj, Luis E. Munoz, Suresh S. Ramalingam
Publikováno v:
Cancer Research. 79:LB-202
Lung cancer is the second most common cancer among men and women and the leading cause of cancer deaths in the world. Despite the advancements in diagnostic technologies and the development of novel treatments in the recent years such as immune check
Autor:
Ramireddy Bommireddy, Haley Lei Huang, Luis E Munoz, Ashwathi P Menon, Suresh Ramalingam, Periasamy Selvaraj
Publikováno v:
The Journal of Immunology. 202:70.7-70.7
Lung cancer is the leading cause of cancer related deaths accounting for approximately 30% of all cancer related mortalities affecting both men and women. Currently, there is no cure for the common non-small cell lung cancer (NSCLC) thus development
Autor:
Ramireddy Bommireddy, Ashwathi P. Menon, Luis E. Munoz, Lei Huang, Janet Kim, Jay Kumar, Ramana Lakshmanan, Suresh S. Ramalingam, Periasamy Selvaraj
Publikováno v:
The Journal of Immunology. 200:181.16-181.16
Lung cancer is the leading cause of cancer related deaths accounting for approximately 30% of all cancer related mortalities affecting both men and women. Currently, there is no cure for the common non-small cell lung cancer (NSCLC) thus development