Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Ashutosh K. Pandey"'
Autor:
Xusheng Wang, Ashutosh K. Pandey, Megan K. Mulligan, Evan G. Williams, Khyobeni Mozhui, Zhengsheng Li, Virginija Jovaisaite, L. Darryl Quarles, Zhousheng Xiao, Jinsong Huang, John A. Capra, Zugen Chen, William L. Taylor, Lisa Bastarache, Xinnan Niu, Katherine S. Pollard, Daniel C. Ciobanu, Alexander O. Reznik, Artem V. Tishkov, Igor B. Zhulin, Junmin Peng, Stanley F. Nelson, Joshua C. Denny, Johan Auwerx, Lu Lu, Robert W. Williams
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Phenome-wide association is a novel method that links sequence variants to a spectrum of phenotypes and diseases. Here the authors generate detailed mouse genetic and phenome data which links their phenome-wide association study (PheWAS) of mouse to
Externí odkaz:
https://doaj.org/article/cfc59303336541d2b8ee796f1a6ebb5b
Autor:
Ashutosh K. Pandey, Baisakhi Majumder, Sarita Keski-Saari, Sari Kontunen-Soppela, Vivek Pandey, Elina Oksanen
Publikováno v:
Climate, Vol 7, Iss 2, p 23 (2019)
Eleven local cultivars of wheat (Triticum aestivum) were chosen to study the effect of ambient ozone (O3) concentration in the Indo-Gangetic Plains (IGP) of India at two high-ozone experimental sites by using 300 ppm of Ethylenediurea (EDU) as a chem
Externí odkaz:
https://doaj.org/article/e119994e854046bfaa8429d440a982e9
Publikováno v:
Mitochondrion. 69:104-115
Autor:
Brianne E, Lewis, Courtney J, Campbell, Andria, Rodrigues, Lindsey, Thompson, Ashutosh K, Pandey, Sarah N, Gallagher, Debkumar, Pain, Andrew, Dancis, Timothy L, Stemmler
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 27:759-773
Mitochondrial [2Fe-2S] cluster biosynthesis is driven by the coordinated activities of the Iron-Sulfur Cluster (ISC) pathway protein machinery. Within the ISC machinery, the protein that provides a structural scaffold on which [2Fe-2S] clusters are a
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-19 (2021)
Molecular Biomedicine
Molecular Biomedicine
The recent emergence of severe acute respiratory syndrome-Corona Virus 2 (SARS-CoV-2) in late 2019 and its spread worldwide caused an acute pandemic of Coronavirus disease 19 (COVID-19). Since then, COVID-19 has been under intense scrutiny as its out
Autor:
David J. Carey, Cristen J. Willer, Anthony Marcketta, Claudia Schurmann, Leland Barnard, John Penn, Suganthi Balasubramanian, Daren Liu, Joseph B. Leader, Gonçalo R. Abecasis, Marcus B. Jones, John C. Whittaker, Ashutosh K. Pandey, Ida Surakka, David H. Ledbetter, Evan Maxwell, John D. Overton, Andrew Blumenfeld, Michael N. Cantor, Robert A. Scott, Wendy K. Chung, Alexander H. Li, Alexander Lopez, Joshua D. Backman, Matthew R. Nelson, Jeffrey Staples, Giovanni Coppola, Jonathan Marchini, Xiaodong Bai, Kavita Praveen, Alan R. Shuldiner, Claudia Gonzaga-Jauregui, Aris N. Economides, Shareef Khalid, William J Salerno, Bin Ye, Cristopher V. Van Hout, Kristian Hveem, Jeffrey G. Reid, Colm O'Dushlaine, Joshua D. Hoffman, Laura M. Yerges-Armstrong, Nilanjana Banerjee, Sean O'Keeffe, Ioanna Tachmazidou, Lon R. Cardon, Alicia Hawes, Aris Baras, Ashish Yadav, George D. Yancopoulos, Lukas Habegger
Publikováno v:
Nature
The UK Biobank is a prospective study of 502,543 individuals, combining extensive phenotypic and genotypic data with streamlined access for researchers around the world1. Here we describe the release of exome-sequence data for the first 49,960 study
Autor:
Jae Lee, Ashutosh K. Pandey, Sundararajan Venkatesh, Jayapalraja Thilagavathi, Tadashi Honda, Kamal Singh, Carolyn K. Suzuki
Publikováno v:
The Journal of biological chemistry. 298(3)
The mitochondrial protein LonP1 is an ATP-dependent protease that mitigates cell stress and calibrates mitochondrial metabolism and energetics. Biallelic mutations in the LONP1 gene are known to cause a broad spectrum of diseases, and LonP1 dysregula
Autor:
Jayashree Pain, Ashutosh K. Pandey, Heeyong Yoon, Simon A.B. Knight, Debkumar Pain, Andrew Dancis
Publikováno v:
Mitochondrion
Rim2 is an unusual mitochondrial carrier protein capable of transporting both iron and pyrimidine nucleotides. Here we characterize two point mutations generated in the predicted substrate-binding site, finding that they yield disparate effects on ir
Publikováno v:
J Biol Chem
Iron–sulfur clusters are essential cofactors of proteins. In eukaryotes, iron–sulfur cluster biogenesis requires a mitochondrial iron–sulfur cluster machinery (ISC) and a cytoplasmic iron–sulfur protein assembly machinery (CIA). Here we used
Autor:
Ashutosh K. Pandey, Graeme A. M. Nimmo, Jessie M. Cameron, Peter N. Ray, Carolyn K. Suzuki, Kamalendra Singh, Lili-Naz Hazrati, Susan Blaser, Sundararajan Venkatesh, Sohnee Ahmed, Grace Yoon, Christian R. Marshall
Publikováno v:
Human Molecular Genetics. 28:290-306
LonP1 is crucial for maintaining mitochondrial proteostasis and mitigating cell stress. We identified a novel homozygous missense LONP1 variant, c.2282 C > T, (p.Pro761Leu), by whole-exome and Sanger sequencing in two siblings born to healthy consang