Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Ashu Chawla"'
Autor:
Alba Grifoni, Hannah Voic, Esther Dawen Yu, Jose Mateus, Kai Mei Yan Fung, Alice Wang, Grégory Seumois, Aruna D. De Silva, Rashika Tennekon, Sunil Premawansa, Gayani Premawansa, Rashmi Tippalagama, Ananda Wijewickrama, Ashu Chawla, Jason Greenbaum, Bjoern Peters, Vijayanand Pandurangan, Daniela Weiskopf, Alessandro Sette
Publikováno v:
Vaccines, Vol 10, Iss 4, p 612 (2022)
While several lines of evidence suggest a protective role of T cells against disease associated with Dengue virus (DENV) infection, their potential contribution to immunopathology in the acute phase of DENV infection remains controversial, and it has
Externí odkaz:
https://doaj.org/article/97469ca26a384d278e732114634f117f
Autor:
Shilpi Chandra, James Gray, William B. Kiosses, Archana Khurana, Kaori Hitomi, Catherine M. Crosby, Ashu Chawla, Zheng Fu, Meng Zhao, Natacha Veerapen, Stewart K. Richardson, Steven A. Porcelli, Gurdyal Besra, Amy R. Howell, Sonia Sharma, Bjoern Peters, Mitchell Kronenberg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
The CD1d pathway present lipid antigens resulting in the activation of iNKT cells but the complete pathway remains to be fully elucidated. Here, Chandra et al. use an siRNA screen and identify Mrp1 as crucial for CD1d lipid presentation and activatio
Externí odkaz:
https://doaj.org/article/4dce5c3c771f4a1abdb502245e1a6bb5
Autor:
Meng Zhao, Mattias N. D. Svensson, Koen Venken, Ashu Chawla, Shu Liang, Isaac Engel, Piotr Mydel, Jeremy Day, Dirk Elewaut, Nunzio Bottini, Mitchell Kronenberg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Invariant natural killer T (iNKT) cells can be subsetted based on their cytokine productions. Here the authors show, using Zap70 mutant mice, that interferon-γ secreting (IFN-γ) iNKT cells may be induced by hampered T cell receptor signallings to h
Externí odkaz:
https://doaj.org/article/2bd3a4ecc15d4e2986a66ad37a5d8be1
Autor:
Bernadette A. Chua, Connor J. Lennan, Mary Jean Sunshine, Daniela Dreifke, Ashu Chawla, Eric J. Bennett, Robert A.J. Signer
Publikováno v:
Cell Stem Cell. 30:460-472.e6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86bf7c70824c4945714689d4ca489a9f
https://doi.org/10.1016/j.stem.2023.02.010
https://doi.org/10.1016/j.stem.2023.02.010
Autor:
Haruka Miki, William B. Kiosses, Mario C. Manresa, Rinkesh K. Gupta, Gurupreet S. Sethi, Rana Herro, Ricardo Da Silva Antunes, Paramita Dutta, Marina Miller, Kai Fung, Ashu Chawla, Katarzyna Dobaczewska, Ferhat Ay, David H. Broide, Alexei V. Tumanov, Michael Croft
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:976-990.e5
Dysregulation of airway smooth muscle cells (ASM) is central to the severity of asthma. Which molecules dominantly control ASM in asthma is unclear. High levels of the cytokine LIGHT (aka TNFSF14) have been linked to asthma severity and lower baselin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabb1045fce2c8049b9bf79ca505f046
https://doi.org/10.1016/j.jaci.2022.11.016
https://doi.org/10.1016/j.jaci.2022.11.016
Autor:
Joseph S, Dolina, Joey, Lee, Eugene L, Moore, Jennifer L, Hope, Donald T, Gracias, Takaji, Matsutani, Ashu, Chawla, Jason A, Greenbaum, Joel, Linden, Stephen P, Schoenberger
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(10)
SignificanceThe CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6914cffa90c01bf117c75d38d06fe244
https://pubmed.ncbi.nlm.nih.gov/35312353
https://pubmed.ncbi.nlm.nih.gov/35312353
Autor:
Joseph S. Dolina, Joey Lee, Eugene L. Moore, Jennifer L. Hope, Donald T. Gracias, Takaji Matsutani, Ashu Chawla, Jason A. Greenbaum, Joel Linden, Stephen P. Schoenberger
Publikováno v:
Proceedings of the National Academy of Sciences. 119
SignificanceThe CD4+Tregresponse following acuteListeriainfection is heterogeneous and deploys two distinct modes of suppression coinciding with initial pathogen exposure and resolution of infection. This bimodal suppression of CD8+T cells during pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1515503b378a728885558e366f16e164
https://doi.org/10.1073/pnas.2113329119
https://doi.org/10.1073/pnas.2113329119
Autor:
Shilpi Chandra, Gabriel Ascui, Thomas Riffelmacher, Ashu Chawla, Ciro Ramirez-Suastegui, Viankail Cedillo Castelan, Gregory Seumois, Hayley Simon, Mallory Paynich Murray, Goo-Young Seo, Ashmitaa Logandha Ramamoorthy Premlal, Greet Verstichel, Yingcong Li, Chia-Hao Lin, Jason Greenbaum, John Lamberti, Raghav Murthy, John Nigro, Hilde Cheroutre, Christian H. Ottensmeier, Stephen M. Hedrick, Li-Fan Lu, Pandurangan Vijayanand, Mitchell Kronenberg
Mucosal-associated invariant T (MAIT) cells are a subpopulation of T lymphocytes that respond to microbial metabolites. We performed single-cell RNA sequencing and metabolic analyses of MAIT cell subsets in thymus and peripheral tissues from mice and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc0cfdc0713c6e65102b13d2dc0e0788
https://doi.org/10.1101/2021.12.20.473182
https://doi.org/10.1101/2021.12.20.473182
Autor:
Bjoern Peters, K. M. Y. Fung, J. Greenbaum, Ashu Chawla, Gayani Premawansa, Sunil Premawansa, Jose Mateus, Alessandro Sette, Hannah Voic, Ananda Wijewickrama, V. Pandagrundan, A. Wang, Daniela Weiskopf, Alba Grifoni, Grégory Seumois, R. Tennekon, D. D. De Silva, Rashmi Tippalagama
While several lines of evidence suggest a protective role of T cells against disease associated with Dengue virus (DENV) infection, their potential contribution to immunopathology in the acute phase of DENV infection remains controversial, and it has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0937728c4dc8b833436774c06e14bfb4
https://doi.org/10.1101/2021.09.01.21262833
https://doi.org/10.1101/2021.09.01.21262833
Autor:
Bernadette Anne Chua, Connor J Lennan, Mary Jean Sunshine, Ashu Chawla, Lorena H San Jose, Daniela Dreifke, Eric J Bennett, Robert Signer
Publikováno v:
Blood. 140:5723-5723
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9722080f5403fbccdeec15a425b9fe90
https://doi.org/10.1182/blood-2022-163857
https://doi.org/10.1182/blood-2022-163857