Fourier‐transform infrared spectroscopy of biofluids: A practical approach

Autor: Ashton G. Theakstone, Christopher Rinaldi, Holly J. Butler, James M. Cameron, Lily Rose Confield, Samantha H. Rutherford, Alexandra Sala, Sayali Sangamnerkar, Matthew J. Baker

Publikováno v: Translational Biophotonics, Vol 3, Iss 2, Pp n/a-n/a (2021)

Abstract Biofluid spectroscopy is an emerging technology in the field of clinical investigation, providing a simple way to extract diagnostic and observational information from easy to acquire samples. Infrared spectroscopy is well suited to analyse

Externí odkaz: https://doaj.org/article/334920f262784cf3ab9dc81db3fc1102

Liquid Biopsy for Pancreatic Cancer Detection Using Infrared Spectroscopy

Autor: Alexandra Sala, James M. Cameron, Cerys A. Jenkins, Hugh Barr, Loren Christie, Justin J. A. Conn, Thomas R. Jeffry Evans, Dean A. Harris, David S. Palmer, Christopher Rinaldi, Ashton G. Theakstone, Matthew J. Baker

Publikováno v: Cancers; Volume 14; Issue 13; Pages: 3048

Pancreatic cancer claims over 460,000 victims per year. The carbohydrate antigen (CA) 19-9 test is the blood test used for pancreatic cancer’s detection; however, its levels can be raised in symptomatic patients with other non-malignant diseases, o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc878efa9ad42b693899f28016455392

The identification of synthetic cannabinoids surface coated on herbal substrates using solid-state nuclear magnetic resonance spectroscopy

Autor: Luke A. O'Dell, James R. Pearson, Xavier A. Conlan, Niki K. Burns, Trent D. Ashton, Haijin Zhu, Frederick M. Pfeffer, Ashton G. Theakstone

Publikováno v: Analytica Chimica Acta. 1104:105-109

Solid-state 13C and 19F NMR spectroscopy offers a non-destructive, highly selective protocol for the identification of forensically relevant synthetic cannabinoids on herbal substrates. Using this technique, well resolved 13C spectra were obtained th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7458c65a2f398ca3b6d00cabf1068f
https://doi.org/10.1016/j.aca.2019.12.051

Abstract 5923: Rapid spectroscopic liquid biopsy for the early detection of brain tumors

Autor: Alexandra Sala, Ashton G. Theakstone, Paul M. Brennan, Michael D. Jenkinson, Samantha J. Mills, Khaja Syed, Christopher Rinaldi, Yun Xu, Royston Goodacre, Holly J. Butler, David S. Palmer, Benjamin R. Smith, Matthew J. Baker

Publikováno v: Cancer Research. 82:5923-5923

To support the early detection and diagnosis of brain tumors we have developed a rapid, cost-effective and easy to use spectroscopic liquid biopsy based on the absorbance of infrared radiation. We have previously reported highly sensitive results of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f93438c2b2cdce07e958d67a41be15a
https://doi.org/10.1158/1538-7445.am2022-5923

Rapid Spectroscopic Liquid Biopsy for the Universal Detection of Brain Tumours

Autor: Yun Xu, Benjamin Smith, David S. Palmer, Michael D. Jenkinson, Holly J. Butler, Royston Goodacre, Matthew J. Baker, Christopher Rinaldi, Ashton G. Theakstone, Khaja Syed, Samantha J Mills, Paul Brennan

Publikováno v: Cancers
Volume 13
Issue 15
Cancers, Vol 13, Iss 3851, p 3851 (2021)
Theakstone, A G, Brennan, P M, Jenkinson, M D, Mills, S J, Syed, K, Rinaldi, C, Xu, Y, Goodacre, R, Butler, H J, Palmer, D S, Smith, B R & Baker, M J 2021, ' Rapid Spectroscopic Liquid Biopsy for the Universal Detection of Brain Tumours ', Cancers, vol. 13, no. 15, pp. 3851 . https://doi.org/10.3390/cancers13153851

Simple Summary Due to the non-specific symptoms of brain cancer (e.g., headaches or memory changes), gliomas will often remain undetected until they are larger or at a higher grade, reducing the patient’s likelihood of a good clinical outcome. Earl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a15112ddc5b719b1b41c7be77dbdff