Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ashton Easterday"'
Autor:
Kathleen M C Sullivan, Marta Vilalta, Linda S Ertl, Yu Wang, Carolyn Dunlap, Karen Ebsworth, Bin N Zhao, Shijie Li, Yibin Zeng, Zhenhua Miao, Pingchen Fan, Venkat Mali, Christopher Lange, Darren McMurtrie, Ju Yang, Rebecca Lui, Ryan Scamp, Vicky Chhina, Alice Kumamoto, Simon Yau, Ton Dang, Ashton Easterday, Shirley Liu, Shichang Miao, Israel Charo, Thomas J Schall, Penglie Zhang
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0286724 (2023)
The interaction of PD-L1 with PD-1 is a major immune checkpoint that limits effector T cell function against cancer cells; monoclonal antibodies that block this pathway have been approved in multiple tumor indications. As a next generation therapy, s
Externí odkaz:
https://doaj.org/article/a53419583b96441186b367f58673ff4f
Autor:
Ton Dang, Ashton Easterday, Rajinder Singh, Kathleen Sullivan, Christopher I. Li, Yu Wang, Yibin Zeng, Penglie Zhang, Scamp Ryan J, Christopher S. Lange, Pingchen Fan, Thomas J. Schall, Niky Zhao, Darren Mcmurtrie, Shirley Liu, Ju Yang, Linda S. Ertl, Ryan Ong, Lui Rebecca M, Vicky Chhina, Marta Vilalta, Israel F. Charo, Alice Kumamoto
Publikováno v:
Cancer Research. 81:1274-1274
Introduction: Cancer cells can escape tumor-specific T cell responses via engagement of inhibitory immune checkpoints. PD-L1/PD-1 interaction is one of the major checkpoints that limit effector T cell function against cancer cells, and monoclonal ant
Autor:
Thomas J. Schall, Ashton Easterday, Christopher S. Lange, Pingchen Fan, Shirley Liu, Rajinder Singh, Penglie Zhang, Ton Dang, Yu Wang, Linda S. Ertl, Marta Vilalta, Yibin Zeng, Israel F. Charo, Simon Yau, Shijie 'Chris' Li, Alice Kumamoto, Ju Yang, Darren Mcmurtrie, Ryan Ong, Lui Rebecca M, Vicky Chhina
Publikováno v:
Cancer Research. 80:5693-5693
Introduction: Antibody-based therapies targeting the Programmed cell Death-1/ Programmed Death-Ligand 1 (PD-1/PD-L1) immune checkpoint axis have achieved great success in cancer immunotherapy in recent years. As a next generation therapy, small molec
Publikováno v:
The FASEB Journal. 22