Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Ashten N, Omstead"'
Autor:
Hirsch Matani, Divya Sahu, Michael Paskewicz, Anastasia Gorbunova, Ashten N. Omstead, Rodney Wegner, Gene G. Finley, Blair A. Jobe, Ronan J. Kelly, Ali H. Zaidi, Ajay Goel
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-10 (2022)
Abstract Background Esophageal adenocarcinoma is a lethal disease. For locally advanced patients, neoadjuvant chemoradiotherapy followed by surgery is the standard of care. Risk stratification relies heavily on clinicopathologic features, particularl
Externí odkaz:
https://doaj.org/article/178cde6cc10e4888acb8aff864a4df0f
Autor:
Ali H. Zaidi, Muhammad Yogi Pratama, Ashten N. Omstead, Anastasia Gorbonova, Rubab Mansoor, Rachael Melton-Kreft, Blair A. Jobe, Patrick L. Wagner, Ronan J. Kelly, Ajay Goel
Publikováno v:
British Journal of Cancer. 127:2016-2024
Emerging evidence indicates the potential clinical significance of specific microbial signatures as diagnostic and prognostic biomarkers, in multiple cancers. However, to date, no studies have systematically interrogated circulating metagenome profil
Autor:
Ashten N Omstead, Michael Paskewicz, Anastasia Gorbunova, Ping Zheng, Madison S Salvitti, Rubab Mansoor, Payton Reed, Sydne Ballengee, Patrick L Wagner, Blair A Jobe, Ronan J Kelly, Ali H Zaidi
Publikováno v:
Carcinogenesis. 43:842-850
Esophageal adenocarcinoma (EAC) is a leading cause of cancer deaths. Pexidartinib, a multi-gene tyrosine kinase inhibitor, through targeting colony-stimulating factor 1 (CSF-1) receptor (CSF-1R), down modulates macrophage-mediated pro-survival tumor
Autor:
Juliann E. Kosovec, Laila Babar, Shahin Ayazi, Gene Grant Finley, Ali H. Zaidi, Soyoung Lee, Blair A. Jobe, Ashten N. Omstead, Madison Salvitti, Ronan J. Kelly, Ping Zheng, Ajay Goel, Anastasia Gorbunova
Publikováno v:
Oncotarget
Background: Esophageal adenocarcinoma (EAC) is a deadly disease with limited treatment options. STING is a transmembrane protein that activates transcription of interferon genes, resulting in stimulation of APCs and enhanced CD8+ T-cell infiltration.
Autor:
Katrin Schwameis, Brittney M. Myers, Andrew D. Grubic, Blair A. Jobe, Adam Alleyne, Ping Zheng, Ashten N. Omstead, Shahin Ayazi, Ali H. Zaidi
Publikováno v:
Surgical Endoscopy
Introduction No manometric criteria have been defined to select patients for magnetic sphincter augmentation (MSA). The first step to establish such criteria is to measure the outflow resistance at esophagogastric junction (EGJ) imposed by MSA. This
Autor:
Pritam Tayshetye, Andrew J. Friday, Ashten N. Omstead, Stacey Miller, Ping Zheng, Prashant Jani, Tanvi Verma, Ali Zaidi, Gene Finley
Publikováno v:
Cancers; Volume 15; Issue 1; Pages: 276
Background: In rectal cancer treatment, neoadjuvant chemoradiation therapy (CRT) is the standard of care and reduces local failure rate. The tumor microenvironment (TME) is a complex entity comprising of tumor cells, immune cells and surrounding stro
Autor:
Ashten N. Omstead, Kristy L. Chovanec, Ali H. Zaidi, Shahin Ayazi, Yoshihiro Komatsu, Nobel Chowdhury, Toshitaka Hoppo, Blair A. Jobe, Ping Zheng
Publikováno v:
Surgical Endoscopy
Introduction Magnetic sphincter augmentation (MSA) is an effective treatment for patients with gastroesophageal reflux disease. In early studies, patients with a hiatal hernia (HH) ≥ 3 cm were excluded from consideration for implantation and initia
Autor:
Matthew A. Smith, Madison Salvitti, Ping Zheng, Ajay Goel, Laila Babar, Vida Jahangiri, Ashten N. Omstead, Ali H. Zaidi, Nobel Chowdhury, Ronan J. Kelly, Juliann E. Kosovec, Blair A. Jobe
Publikováno v:
Oncotarget
Treatment options and risk stratification for esophageal adenocarcinomas (EAC) currently rely on pathological criteria such as tumor staging. However, with advancement in immune modulated treatments, there is a need for accurate predictive biomarkers
Autor:
Nicholas G. Smith, Lindsey T. Saldin, Luai Huleihel, Neill J. Turner, Ali H. Zaidi, Christopher C. Chung, Ashten N. Omstead, Xue Li, Anant K. Bajwa, David Nascari, Li Zhang, Lina M. Quijano, Shil Patel, George S. Hussey, Juliann E. Kosovec, Blair A. Jobe, Divya Raghu, Stephen F. Badylak
Publikováno v:
Tissue Engineering Part A. 25:487-498
Extracellular matrix (ECsM) bioscaffolds have been successfully used to treat five esophageal adenocarcinoma (EAC) patients following resection of neoplastic mucosal tissue. The present study evaluated the in vitro effect of ECM harvested from nonmal
Autor:
Margaret Riccardi, Steven Tamesis, Ping Zheng, Sven Eriksson, Ashten N. Omstead, Blair Jobe, Shahin Ayazi
Publikováno v:
Gastroenterology. 162:S-1317