Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Ashrafali M. Ismail"'
Autor:
Ashrafali M. Ismail, Ji Sun Lee, Jeong Yoon Lee, Gurdeep Singh, David W. Dyer, Donald Seto, James Chodosh, Jaya Rajaiya
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/aaad5329e842475a99cbb27df05a722e
Publikováno v:
Viruses, Vol 13, Iss 2, p 293 (2021)
Human adenoviruses cause disease at multiple mucosal sites, including the respiratory, gastrointestinal, and genitourinary tracts, and are common agents of conjunctivitis. One site of infection that has received sparse attention is the cornea, a tran
Externí odkaz:
https://doaj.org/article/d802ed7bcb3e43e286f49c93010e81ee
Autor:
Ashrafali M. Ismail, Ji Sun Lee, Jeong Yoon Lee, Gurdeep Singh, David W. Dyer, Donald Seto, James Chodosh, Jaya Rajaiya
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Human adenovirus (HAdV) infections cause disease world-wide. Whole genome sequencing has now distinguished 90 distinct genotypes in 7 species (A-G). Over half of these 90 HAdVs fall within species D, with essentially all of the HAdV-D whole genome se
Externí odkaz:
https://doaj.org/article/f6de00cbefbb41a18bbca5c69a5fe902
Autor:
Jeong Yoon Lee, Ji Sun Lee, Emma C. Materne, Rahul Rajala, Ashrafali M. Ismail, Donald Seto, David W. Dyer, Jaya Rajaiya, James Chodosh
Publikováno v:
mSphere, Vol 3, Iss 3 (2018)
ABSTRACT Adenovirus infections in humans are common and sometimes lethal. Adenovirus-derived vectors are also commonly chosen for gene therapy in human clinical trials. We have shown in previous work that homologous recombination between adenoviral g
Externí odkaz:
https://doaj.org/article/ffe2324aec3f48e59fea24b7d3d2bd13
Autor:
Matthew R. Pennington, Amrita Saha, David F. Painter, Christina Gavazzi, Ashrafali M. Ismail, Xiaohong Zhou, James Chodosh, Jaya Rajaiya
Publikováno v:
Microorganisms, Vol 7, Iss 9, p 351 (2019)
Human adenovirus infection of the ocular surface is associated with severe keratoconjunctivitis and the formation of subepithelial corneal infiltrates, which may persist and impair vision for months to years following infection. Long term pathology p
Externí odkaz:
https://doaj.org/article/191148ad0285460fab23f5e870864abe
Autor:
Gurdeep Singh, Ashrafali M. Ismail, Jeong Yoon Lee, Mirja Ramke, Ji Sun Lee, David W. Dyer, Donald Seto, Jaya Rajaiya, James Chodosh
Publikováno v:
Viruses, Vol 11, Iss 2, p 143 (2019)
Adenovirus E1A is the first viral protein expressed during infection. E1A controls critical aspects of downstream viral gene expression and cell cycle deregulation, and its function is thought to be highly conserved among adenoviruses. Various bioinf
Externí odkaz:
https://doaj.org/article/a95c2ed0cc394bf090bb494485b05043
Autor:
Haibin Pan, Yuqian Yan, Jing Zhang, Shan Zhao, Liqiang Feng, Junxian Ou, Na Cao, Min Li, Wei Zhao, Chengsong Wan, Ashrafali M. Ismail, Jaya Rajaiya, James Chodosh, Qiwei Zhang
Publikováno v:
Viruses, Vol 10, Iss 10, p 568 (2018)
In 1955, Human adenovirus type 14 (HAdV-B14p) was firstly identified in a military trainee diagnosed as acute respiratory disease (ARD) in the Netherlands. Fifty years later, a genomic variant, HAdV-B14p1, re-emerged in the U.S. and caused large and
Externí odkaz:
https://doaj.org/article/35eb03d448294bd28fb13f1a995ef823
Publikováno v:
FEBS Lett
Human adenovirus (HAdV) commonly causes infections of respiratory, gastrointestinal, genitourinary, and ocular surface mucosae. Although most adenovirus eye infections are mild and self-limited, specific viruses within human adenovirus species D (HAd
Autor:
Ashrafali M. Ismail, Amrita Saha, Ji S. Lee, David F. Painter, Yinghua Chen, Gurdeep Singh, Gabriela N. Condezo, James Chodosh, Carmen San Martín, Jaya Rajaiya
Publikováno v:
PLoS pathogens. 18(6)
As intracellular parasites, viruses exploit cellular proteins at every stage of infection. Adenovirus outbreaks are associated with severe acute respiratory illnesses and conjunctivitis, with no specific antiviral therapy available. An adenoviral vac
Autor:
Rebecca A. Halpin, Leonardo J. Ferreyra, Nadia Fedorova, Jason Seto, Morris S. Jones, Shoaleh Dehghan, Regis P. Kowalski, K.L. Therese, Susmita Shrivastava, Ashrafali M. Ismail, Gurdeep Singh, Ramana Madupu, Jaya Rajaiya, Jambulingam Malathi, Donald Seto, Timothy B. Stockwell, Qiwei Zhang, Kalpana Dommaraju, Tiange Cui, Neha Gupta, Eric G. Romanowski, David W. Dyer, Adriana E. Kajon, Hajib Narahari Madhavan, James Chodosh, Albert Heim
Publikováno v:
Emerging Microbes & Infections
Human adenoviruses (HAdVs) are uniquely important "model organisms" as they have been used to elucidate fundamental biological processes, are recognized as complex pathogens, and are used as remedies for human health. As pathogens, HAdVs may effect a