Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Ashraf Yusuf Rangrez"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/9fcfbd73a3ce43cf9ee9a600357a5e1a
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-21 (2022)
Abstract The molecular mechanisms that regulate embryogenesis and cardiac development are calibrated by multiple signal transduction pathways within or between different cell lineages via autocrine or paracrine mechanisms of action. The heart is the
Externí odkaz:
https://doaj.org/article/e305af204157459fb192cca46cba4dd0
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-21 (2021)
Abstract The Ras homolog gene family member A (RhoA) is the founding member of Rho GTPase superfamily originally studied in cancer cells where it was found to stimulate cell cycle progression and migration. RhoA acts as a master switch control of act
Externí odkaz:
https://doaj.org/article/a53d6e369daf45159e30af3ec2f0ad60
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-14 (2020)
Abstract Post-translational modifications (PTMs) are crucial for the adaptation of various signalling pathways to ensure cellular homeostasis and proper adaptation to stress. PTM is a covalent addition of a small chemical functional group such as a p
Externí odkaz:
https://doaj.org/article/1ab970012b6f405eba3ec2aff1c64f7c
Autor:
Anushka Deshpande, Ankush Borlepawar, Alexandra Rosskopf, Derk Frank, Norbert Frey, Ashraf Yusuf Rangrez
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11042 (2021)
Congenital heart disease (CHD) is one of the most common birth defects in humans, present in around 40% of newborns with Down’s syndrome (DS). The SH3 domain-binding glutamic acid-rich (SH3BGR) gene, which maps to the DS region, belongs to a gene f
Externí odkaz:
https://doaj.org/article/71f592bcc06f472e973fe3ad9fa79006
Publikováno v:
Cells, Vol 10, Iss 7, p 1681 (2021)
Chronic inflammation, the activation of immune cells and their cross-talk with cardiomyocytes in the pathogenesis and progression of heart diseases has long been overlooked. However, with the latest research developments, it is increasingly accepted
Externí odkaz:
https://doaj.org/article/c18b6d25edbb4cefa57ad2b7d5c64ef2
Autor:
Hatim Seoudy, Johanne Frank, Markus Neu, Nathalie Güßefeld, Yannic Klaus, Sandra Freitag‐Wolf, Moritz Lambers, Georg Lutter, Astrid Dempfle, Ashraf Yusuf Rangrez, Christian Kuhn, Norbert Frey, Derk Frank
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 3 (2019)
Background Cardiovascular biomarkers constitute promising tools for improved risk stratification and prediction of outcome in patients undergoing transcatheter aortic valve implantation. We examined the association of periprocedural changes of NT‐p
Externí odkaz:
https://doaj.org/article/3720a9ac286f4e8aab3260897f9d1ce1
Autor:
Ankush Borlepawar, Nesrin Schmiedel, Matthias Eden, Lynn Christen, Alexandra Rosskopf, Derk Frank, Renate Lüllmann-Rauch, Norbert Frey, Ashraf Yusuf Rangrez
Publikováno v:
Cells, Vol 9, Iss 11, p 2390 (2020)
Dysbindin, a schizophrenia susceptibility marker and an essential constituent of BLOC-1 (biogenesis of lysosome-related organelles complex-1), has recently been associated with cardiomyocyte hypertrophy through the activation of Myozap-RhoA-mediated
Externí odkaz:
https://doaj.org/article/ff1ba9050db645b4970ab5f703d06d13
Autor:
Ashraf Yusuf Rangrez, Phillip Hoppe, Christian Kuhn, Elisa Zille, Johanne Frank, Norbert Frey, Derk Frank
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0183901 (2017)
Calsarcin-1 deficient mice develop dilated cardiomyopathy (DCM) phenotype in pure C57BL/6 genetic background (Cs1-ko) despite severe contractile dysfunction and robust activation of fetal gene program. Here we performed a microRNA microarray to ident
Externí odkaz:
https://doaj.org/article/a717bfb36e1244dbb878070756c1000b
Autor:
Ashraf Yusuf Rangrez, Eléonore M'Baya-Moutoula, Valérie Metzinger-Le Meuth, Lucie Hénaut, Mohamed Seif el Islam Djelouat, Joyce Benchitrit, Ziad A Massy, Laurent Metzinger
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47807 (2012)
BACKGROUND: An elevated serum inorganic phosphate (Pi) level is a major risk factor for kidney disease and downstream vascular complications. We focused on the effect of Pi levels on human aortic vascular smooth muscle cells (VSMCs), with an emphasis
Externí odkaz:
https://doaj.org/article/484adf6a4c954daa9415edd043cf48c0