Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ashraf Shabaneh"'
ALAN is a computational approach that interprets genomic findings in the context of tumor ecosystems
Autor:
Hannah E. Bergom, Ashraf Shabaneh, Abderrahman Day, Atef Ali, Ella Boytim, Sydney Tape, John R. Lozada, Xiaolei Shi, Carlos Perez Kerkvliet, Sean McSweeney, Samuel P. Pitzen, Megan Ludwig, Emmanuel S. Antonarakis, Justin M. Drake, Scott M. Dehm, Charles J. Ryan, Jinhua Wang, Justin Hwang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Gene behavior is governed by activity of other genes in an ecosystem as well as context-specific cues including cell type, microenvironment, and prior exposure to therapy. Here, we developed the Algorithm for Linking Activity Networks (ALAN)
Externí odkaz:
https://doaj.org/article/beba2e91e3c64bb1936e18c40ebe3097
Autor:
Arsheed A. Ganaie, Aijaz Parray, Tabish Hussain, Ashraf Shabaneh, Anmbreen Jamroze, Marina G. Ferrari, Lei Wang, D. Joshua Liao, Shahriar Koochekpour, Sanjeev Nanda, Jinhua Wang, Yibin Deng, Sergio A Gradilone, Edward H. Hinchcliffe, Badrinath R. Konety, Mohammad Saleem
Publikováno v:
Translational Oncology, Vol 12, Iss 8, Pp 1056-1071 (2019)
Therapy failure and metastasis-associated mortality are stumbling blocks in the management of PDAC in patients. Failure of therapy is associated to intense hypoxic conditions of tumors. To develop effective therapies, a complete understanding of hypo
Externí odkaz:
https://doaj.org/article/8b84d9c2c20e45bc9e8e04634c0dff6a
Autor:
Mohammad Saleem, Badrinath R. Konety, Christopher A. Warlick, Noona Ambartsumian, Jinhua Wang, Jörg Klingelhöfer, Paari Murugan, Marina G. Ferrari, Ashraf Shabaneh, Hifzur R. Siddique, Arpit Rao, Tabish Hussain, Adrian P. Mansini, Arsheed A. Ganaie
(Ai) Box-plot shows the association of copy number of S100A4 gene to Gleason Score of prostate tumors in CaP patients. The graph was generated from the analysis of TCGA clinical data using Oncomine platform. (Aii) Image shows the detection of S100A4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e935a4c1fe1fc23736beff519d270f0
https://doi.org/10.1158/1535-7163.22519167
https://doi.org/10.1158/1535-7163.22519167
Autor:
Grant Hogg, Tong Liu, Helen Cao, Adib Shafi, Ashraf Shabaneh, John Howitt, Amanda Williamson, Rachel Dango, Xiaojun Guan, Heidi Hoffmann, Michael Mooney, John Pruitt, Scott Parker, Stan Letovsky, Li Cai, Eric A. Severson, Shakti Ramkissoon, Anjen Chenn, Marcia Eisenberg, Eyad Almasri, Taylor Jensen
Publikováno v:
Cancer Research. 83:6220-6220
Introduction: Accurate diagnosis, prognosis and treatment of hematologic disorders from both myeloid and lymphoid origin requires assessing somatic mutation status in an increasingly large number of genes. Here we present the results of the assay dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7793a2b87c8fb80fcdc66ed52b334399
https://doi.org/10.1158/1538-7445.am2023-6220
https://doi.org/10.1158/1538-7445.am2023-6220
Autor:
Hifzur R. Siddique, Mohammad Saleem, Jörg Klingelhöfer, Jinhua Wang, Christopher A. Warlick, Adrian P. Mansini, Paari Murugan, Ashraf Shabaneh, Badrinath R. Konety, Arpit Rao, Arsheed A. Ganaie, Tabish Hussain, Noona Ambartsumian, Marina G. Ferrari
Publikováno v:
Molecular Cancer Therapeutics. 19:2598-2611
S100A4 oncoprotein plays a critical role during prostate cancer progression and induces immunosuppression in host tissues. We hypothesized that S100A4-regulated oncogenic activity in immunosuppressed prostate tumors promotes growth of neoplastic cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e76565fa662cbba448cbd098a45f4f6
https://doi.org/10.1158/1535-7163.mct-20-0410
https://doi.org/10.1158/1535-7163.mct-20-0410
Autor:
Najla El Jurdi, Ashraf Shabaneh, Brian C. Betts, Armin Rashidi, Margaret L. MacMillan, Mukta Arora, Todd E DeFor, Daniel D Miller, Brittney Schultz, Angela Mortari, Daniel Weisdorf, Jinhua Wang, Shernan Holtan
Publikováno v:
Transplantation and Cellular Therapy. 28:S28-S29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::128def0ec8bc5ac20689551a725d12c7
https://doi.org/10.1016/s2666-6367(22)00192-0
https://doi.org/10.1016/s2666-6367(22)00192-0
Autor:
Edward H. Hinchcliffe, Tabish Hussain, Marina G. Ferrari, Shahriar Koochekpour, Anmbreen Jamroze, Arsheed A. Ganaie, Sergio A. Gradilone, Aijaz Parray, Lei Wang, Sanjeev Nanda, D. Joshua Liao, Ashraf Shabaneh, Yibin Deng, Jinhua Wang, Badrinath R. Konety, Mohammad Saleem
Publikováno v:
Translational Oncology, Vol 12, Iss 8, Pp 1056-1071 (2019)
Translational Oncology
Translational Oncology
Therapy failure and metastasis-associated mortality are stumbling blocks in the management of PDAC in patients. Failure of therapy is associated to intense hypoxic conditions of tumors. To develop effective therapies, a complete understanding of hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b809d8d12d3ffe1188e4f5da50a8e4
https://doi.org/10.1016/j.tranon.2019.05.002
https://doi.org/10.1016/j.tranon.2019.05.002
Autor:
Allison P, Watson, Ashraf, Shabaneh, Jinhua, Wang, Scott M, Dehm, Arpit, Rao, Charles J, Ryan
Publikováno v:
Am J Clin Exp Urol
Background: Aberrations in TP53, PTEN and RB1 are key drivers of therapy resistance in prostate cancer. Up to 50% of prostate cancers harbor ETS gene rearrangements, a potentially compounding aggressive biological event. Little is known about the imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63b77891488aa695a9beb73c01559480
https://pubmed.ncbi.nlm.nih.gov/32929406
https://pubmed.ncbi.nlm.nih.gov/32929406
Autor:
Arsheed A, Ganaie, Adrian P, Mansini, Tabish, Hussain, Arpit, Rao, Hifzur R, Siddique, Ashraf, Shabaneh, Marina G, Ferrari, Paari, Murugan, Jörg, Klingelhöfer, Jinhua, Wang, Noona, Ambartsumian, Christopher A, Warlick, Badrinath R, Konety, Mohammad, Saleem
Publikováno v:
Molecular cancer therapeutics. 19(12)
S100A4 oncoprotein plays a critical role during prostate cancer progression and induces immunosuppression in host tissues. We hypothesized that S100A4-regulated oncogenic activity in immunosuppressed prostate tumors promotes growth of neoplastic cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05c473f7c9645903e4cd469e3e01ce06
https://pubmed.ncbi.nlm.nih.gov/32999046
https://pubmed.ncbi.nlm.nih.gov/32999046
Autor:
Pamala A. Jacobson, Daniel J. Weisdorf, Qing Cao, Isha Gandhi, Shernan G. Holtan, Arne Slungaard, Veronika Bachanova, Brian C. Betts, Claudio G. Brunstein, Angela Panoskaltsis-Mortari, Celalettin Ustun, Margaret L. MacMillan, Chi Chen, John E. Wagner, Armin Rashidi, Fiona He, Jinhua Wang, Erica D. Warlick, Najla El Jurdi, Bruce R. Blazar, Gregory M. Vercellotti, Andrea Hoeschen, Mukta Arora, Ashraf Shabaneh, Jeffrey S. Miller
Publikováno v:
Blood advances. 4(7)
Acute graft-versus-host disease (aGVHD) is a potentially fatal complication of allogeneic hematopoietic cell transplantation that fails to improve with intense immunosuppression in some patients. We hypothesized that urinary-derived human chorionic g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe46939910b1bbf7272f1f2a166c535b
https://pubmed.ncbi.nlm.nih.gov/32236525
https://pubmed.ncbi.nlm.nih.gov/32236525