Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Ashraf N Abdalla"'
Autor:
Walaa A. Bedewy, Mosaad S. Mohamed, Ahmed M. Abdelhameed, Mohamed A. Elsawy, Mohammed Al-Muhur, Noriyuki Ashida, Ashraf N Abdalla, Tamer A. Elwaie, Tomohisa Nagamatsu, Hamed I. Ali
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Novel 5-deazaflavins were designed as potential anticancer candidates. Compounds 4j, 4k, 5b, 5i, and 9f demonstrated high cytotoxicity against MCF-7 cell line with IC50 of 0.5–190nM. Compounds 8c and 9g showed preferential activity against Hela cel
Externí odkaz:
https://doaj.org/article/3ccb7b98f09f4334a648b495c54b1ef0
Autor:
Youssef Elouafy, Adil El Yadini, Salma Mortada, Mohamed Hnini, Hicham Harhar, Asaad Khalid, Ashraf N Abdalla, Abdelhakim Bouyahya, Khang Wen Goh, Long Chiau Ming, My El Abbes Faouzi, Mohamed Tabyaoui
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 13, Iss 2, Pp 60-69 (2023)
Objective: To investigate the relationship between triterpenoid saponin content and antioxidant, antimicrobial, and α-glucosidase inhibitory activities of 70% ethanolic, butanolic, aqueous, supernate and precipitate extracts of Juglans regia leaves.
Externí odkaz:
https://doaj.org/article/27e48988e79143f6beed32c43afe9565
Autor:
Rehab A. Baghdadi, MD, Ashraf N. Abdalla, PhD, Mohammed A.S. Abourehab, PhD, Alaa S. Tulbah, PhD
Publikováno v:
Journal of Taibah University Medical Sciences, Vol 19, Iss 4, Pp 806-815 (2024)
الملخص: أهداف البحث: داساتينيب هو مثبط تيروزين كيناز من الجيل الثاني. إنه يعمل كدواء جزيء صغير متعدد الأهداف من خلال استهداف كينازات التي
Externí odkaz:
https://doaj.org/article/d79dfd5038514d5ab64416149a0bcded
Publikováno v:
Arab Journal of Basic and Applied Sciences, Vol 31, Iss 1, Pp 454-469 (2024)
A series of phthalazine derivatives have been synthesized using green protocol methods under microwave irradiation. This involved subjecting chlorophthalazine to microwave irradiation and employing various reagents, including hydrazine derivatives, p
Externí odkaz:
https://doaj.org/article/8421861c4e404783b4f52cd0b93dcae1
Autor:
Alshaimaa A. Alnoor, Ashraf N. Abdalla, Fatma M. Abdel Bar, Omer Abdalla Ahmed Hamdi, Mohamed E. Elzubier, Hanaa H. A. Mohmed, Ayman A. Salkini, Masaki Kuse, Ehssan Moglad, Amira Mira
Publikováno v:
Arab Journal of Basic and Applied Sciences, Vol 31, Iss 1, Pp 358-370 (2024)
Acanthospermum hispidum DC (Asteraceae), a traditional medicinal plant, plays a role as an alternative remedy for various diseases, such as bacterial and viral infections, jaundice, malaria, fever, gastrointestinal disorders, headache, convulsions, a
Externí odkaz:
https://doaj.org/article/7676edf3947d47819ba9885f87a6addf
Autor:
Ali Hendi Alghamdi, Asaad Khalid, Aimun A. E. Ahmed, Haidar Abdalgadir, Mahadi Bashir, Ashraf N. Abdalla, Sami S. Ashgar, Hamdi M. Alsaid, Magbool E. Oraiby
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract This study on Buddleja polystachya highlights its phytochemical composition, antimicrobial activity, and cytotoxic impacts. The study emphasizes the plant’s potential to treat ocular diseases by identifying important compounds involved in
Externí odkaz:
https://doaj.org/article/ff7be86485ac4e898018a1e799ffa3fc
Autor:
Saeed Ullah, Atta Ullah, Muhammad Waqas, Sobia Ahsan Halim, Anam Rubbab Pasha, Zahid Shafiq, Suraj N. Mali, Rahul D. Jawarkar, Ajmal Khan, Asaad Khalid, Ashraf N. Abdalla, Hamdy Kashtoh, Ahmed Al-Harrasi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The COVID-19 has had a significant influence on people's lives across the world. The viral genome has undergone numerous unanticipated changes that have given rise to new varieties, raising alarm on a global scale. Bioactive phytochemicals d
Externí odkaz:
https://doaj.org/article/265bf3c587d246698513aea0d000d1a4
Autor:
Nasreddine El Omari, Saad Bakrim, Asaad Khalid, Ashraf N. Abdalla, Mohamed A. M. Iesa, Kawtar El Kadri, Siah Ying Tang, Bey Hing Goh, Abdelhakim Bouyahya
Publikováno v:
Natural Products and Bioprospecting, Vol 14, Iss 1, Pp 1-29 (2024)
Abstract Until recently, the main pharmaceuticals used to control cholesterol and prevent cardiovascular disease (CVD) were statin-related drugs, known for their historical side effects. Therefore, there is growing interest in exploring alternatives,
Externí odkaz:
https://doaj.org/article/9b5bc027757f431489faf17b01748a04
Autor:
Maryam Zulfat, Mohammed Ageeli Hakami, Ali Hazazi, Arif Mahmood, Asaad Khalid, Roaya S. Alqurashi, Ashraf N. Abdalla, Junjian Hu, Abdul Wadood, Xiaoyun Huang
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e34410- (2024)
The NOD-Like Receptor Protein-3 (NLRP3) inflammasome is a key therapeutic target for the treatment of epilepsy and has been reported to regulate inflammation in several neurological diseases. In this study, a machine learning-based virtual screening
Externí odkaz:
https://doaj.org/article/4435d2c0624a45a78043c06bb427b1ba
Autor:
Saad Bakrim, Naoufal El Hachlafi, Asaad Khalid, Ashraf N. Abdalla, Nasreddine El Omari, Sara Aboulaghras, Ashraf M. Sakran, Khang Wen Goh, Long Chiau Ming, Pakhrur Razi, Abdelhakim Bouyahya
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116886- (2024)
Colorectal cancer (CRC) is one of the most significant forms of human cancer. It is characterized by its heterogeneity because several molecular factors are involved in contiguity and can link it to others without having a linear correlation. Among t
Externí odkaz:
https://doaj.org/article/8f4d65386e2a4c54963b5c6d27c66973