Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Ashraf H. Bayoumi"'
Autor:
Waheed A. Zaki, Selwan M. El-Sayed, Mohamed Alswah, Ahmed El-Morsy, Ashraf H. Bayoumi, Abrahman S. Mayhoub, Walaa H. Moustafa, Aeshah A. Awaji, Eun Joo Roh, Ahmed H.E. Hassan, Kazem Mahmoud
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1593 (2023)
CDK2 is a key player in cell cycle processes. It has a crucial role in the progression of various cancers. Hepatocellular carcinoma (HCC) and colorectal cancer (CRC) are two common cancers that affect humans worldwide. The available therapeutic optio
Externí odkaz:
https://doaj.org/article/ec90ed5a69f14606981d05c78b6e9de4
Autor:
Ahmed K. B. Aljohani, Waheed Ali Zaki El Zaloa, Mohamed Alswah, Mohamed A. Seleem, Mohamed M. Elsebaei, Ashraf H. Bayoumi, Ahmed M. El-Morsy, Mohammed Almaghrabi, Aeshah A. Awaji, Ali Hammad, Marwa Alsulaimany, Hany E. A. Ahmed
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 15026 (2023)
Phenylpyrazolo[3,4-d]pyrimidine is considered a milestone scaffold known to possess various biological activities such as antiparasitic, antifungal, antimicrobial, and antiproliferative activities. In addition, the urgent need for selective and poten
Externí odkaz:
https://doaj.org/article/0a56b615b6774e4a8133efe02789d5b2
Autor:
Abdulmalik S. Altamimi, Adel S. El-Azab, Sami G. Abdelhamid, Mubarak A. Alamri, Ashraf H. Bayoumi, Safar M. Alqahtani, Alhumaidi B. Alabbas, Ali I. Altharawi, Manal A. Alossaimi, Menshawy A. Mohamed
Publikováno v:
Molecules, Vol 26, Iss 10, p 2992 (2021)
A new series of 8-methoxy-2-trimethoxyphenyl-3-substituted quinazoline-4(3)-one compounds were designed, synthesized, and screened for antitumor activity against three cell lines, namely, Hela, A549, and MDA compared to docetaxel as reference drug. T
Externí odkaz:
https://doaj.org/article/41f4fd106ff94c578462050ce817e49a
Autor:
Mohamed Hagrs, Ashraf H. Bayoumi, Kamal M. El-Gamal, Abdelrahman S. Mayhoub, Hamada S. Abulkhair
Publikováno v:
Beni-Suef University Journal of Basic and Applied Sciences, Vol 4, Iss 4, Pp 338-345 (2015)
A series of new 6-methoxyquinoline-3-carbonitrile derivatives were synthesized using a variety of synthetic routes. The newly synthesized compounds have been characterized by IR, 1H NMR, and mass spectral data followed by elemental analysis. All of t
Externí odkaz:
https://doaj.org/article/80b4b7552b804e50b6ee5fff4c9f5d7c
Autor:
Mohamed Alswah, Ashraf H. Bayoumi, Kamal Elgamal, Ahmed Elmorsy, Saleh Ihmaid, Hany E. A. Ahmed
Publikováno v:
Molecules, Vol 23, Iss 1, p 48 (2017)
A series of hybrid of triazoloquinoxaline-chalcone derivatives 7a–k were designed, synthesized, fully characterized, and evaluated for their cytotoxic activity against three target cell lines: human breast adenocarcinoma (MCF-7), human colon carcin
Externí odkaz:
https://doaj.org/article/2244d15e153848578bf32223662fd351
Publikováno v:
Medicinal Chemistry Research. 32:369-388
Hepatocellular carcinoma (HCC), also known as hepatoma, is the most prevalent type of primary liver cancer. It begins in the hepatocytes, the liver’s major cell type. Cancer that began in another region of the body but has spread to the liver is kn
Autor:
Hany E.A. Ahmed, Mohamed H. El-Shershaby, Adel Ghiaty, Mona S. El-Zoghbi, Hamada S. Abulkhair, Khaled El-Adl, Ashraf H. Bayoumi
Publikováno v:
New Journal of Chemistry. 45:11136-11152
Targeting PCAF with small inhibitor molecules has emerged as a potential therapeutic strategy for the treatment of cancer. Recently, L-45 was identified as a potent triazolophthalazine inhibitor of the PCAF bromodomain. Here, we report the bioisoster
Autor:
Ahmed A. Al-Karmalamy, Khaled El-Adl, Mohamed H. El-Shershaby, Mohamed Alswah, Hamada S. Abulkhair, Kamal M. El-Gamal, Ashraf H. Bayoumi, Hany E.A. Ahmed
Publikováno v:
New Journal of Chemistry. 45:13986-14004
The resistance of pathogenic microbes to currently available antimicrobial agents has been considered a global alarming concern. Hence, close attention should be paid to the development of novel potent antimicrobials. Herein, we report the synthesis,
Publikováno v:
Arabian Journal of Chemistry, Vol 13, Iss 12, Pp 8920-8934 (2020)
Pharmaceutical and clinicians researchers are looking for novel drug carriers to maintain the drug level in the body in low and effective dose. Thus, the present research concerned with studying the behavior of some natural biomass materials, namely
Publikováno v:
Journal of Heterocyclic Chemistry. 57:4358-4372