Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Ashraf Al-Madhoun"'
Autor:
Nadeem Akhter, Ajit Wilson, Hossein Arefanian, Reeby Thomas, Shihab Kochumon, Fatema Al-Rashed, Mohamed Abu-Farha, Ashraf Al-Madhoun, Fahd Al-Mulla, Rasheed Ahmad, Sardar Sindhu
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15186 (2023)
Obesity and metabolic syndrome involve chronic low-grade inflammation called metabolic inflammation as well as metabolic derangements from increased endotoxin and free fatty acids. It is debated whether the endoplasmic reticulum (ER) stress in monocy
Externí odkaz:
https://doaj.org/article/8552849f3f73410998fa61932acd5471
Autor:
Nadeem Akhter, Ajit Wilson, Reeby Thomas, Fatema Al-Rashed, Shihab Kochumon, Areej Al-Roub, Hossein Arefanian, Ashraf Al-Madhoun, Fahd Al-Mulla, Rasheed Ahmad, Sardar Sindhu
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10519 (2021)
IL-8/MCP-1 act as neutrophil/monocyte chemoattractants, respectively. Oxidative stress emerges as a key player in the pathophysiology of obesity. However, it remains unclear whether the TNF-α/oxidative stress interplay can trigger IL-8/MCP-1 express
Externí odkaz:
https://doaj.org/article/da2c0ea0abbf45fda8e52157ce09a852
Autor:
Texy Jacob, Sardar Sindhu, Amal Hasan, Md. Zubbair Malik, Hossein Arefanian, Fatema Al-Rashed, Rasheeba Nizam, Shihab Kochumon, Reeby Thomas, Fatemah Bahman, Steve Shenouda, Ajit Wilson, Nadeem Akther, Areej Al-Roub, Nermeen Abukhalaf, Shaima Albeloushi, Mohamed Abu-Farha, Ashraf Al Madhoun, Fawaz Alzaid, Thangavel Alphonse Thanaraj, Heikki A. Koistinen, Jaakko Tuomilehto, Fahd Al-Mulla, Rasheed Ahmad
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
High-fat diets (HFDs) shape the gut microbiome and promote obesity, inflammation, and liver steatosis. Fish and soybean are part of a healthy diet; however, the impact of these fats, in the absence of sucrose, on gut microbial dysbiosis and its assoc
Externí odkaz:
https://doaj.org/article/d3ab3726b78f47ddbc7105c15171b775
Autor:
Carlos Gil-Recio, Sheyla Montori, Saddam Al Demour, Mera A. Ababneh, Eduard Ferrés-Padró, Carles Marti, Elvira Ferrés-Amat, Miguel Barajas, Ashraf Al Madhoun, Maher Atari
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Liver diseases are major causes of morbidity and mortality. Dental pulp pluripotent-like stem cells (DPPSCs) are of a considerable promise in tissue engineering and regenerative medicine as a new source of tissue-specific cells; therefore, this study
Externí odkaz:
https://doaj.org/article/d530ec69fcd04f0fb7f344480fc2b042
Autor:
Shihab Kochumon, Ashraf Al Madhoun, Fatema Al-Rashed, Rafaat Azim, Ebaa Al-Ozairi, Fahd Al-Mulla, Rasheed Ahmad
Publikováno v:
Therapeutic Advances in Endocrinology and Metabolism, Vol 11 (2020)
Background: The CXCL subfamily of chemokines (CXCL9, CXCL10, and CXCL11; angiostatic chemokines) plays a key role in many inflammatory diseases. However, the expression of CXCLs in adipose tissue (AT) during obesity and association of these CXCLs wit
Externí odkaz:
https://doaj.org/article/d3bacddad4594ce995901f3794013635
Publikováno v:
International Journal of Infectious Diseases, Vol 96, Iss , Pp 459-460 (2020)
The increasing number of deaths due to the COVID-19 pandemic has raised serious global concerns. Increased testing capacity and ample intensive care availability could explain lower mortality in some countries compared to others. Nevertheless, it is
Externí odkaz:
https://doaj.org/article/db71f4162a284444ab944a8ba80fcddf
Autor:
Ashraf Al Madhoun, Hamad Ali, Sarah AlKandari, Valerie Lopez Atizado, Nadeem Akhter, Fahd Al-Mulla, Maher Atari
Publikováno v:
Stem Cell Research & Therapy, Vol 7, Iss 1, Pp 1-11 (2016)
Abstract Background Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) are gaining increasing interest as an alternative source of stem cells for regenerative medicine applications. Definitive endoderm (DE) specification is a prerequisite for
Externí odkaz:
https://doaj.org/article/b0dbbe2cfc414000b5412fda16d5d1f6
Autor:
Rasheeba Nizam, Ebaa Al-Ozairi, Jo Max Goodson, Motesam Melhem, Lena Davidsson, Hessa Alkhandari, Ashraf Al Madhoun, Sara Shamsah, Malak Qaddoumi, Ghazi Alghanim, Nouf Alhasawi, Mohamed Abu-Farha, Jehad Abubaker, Ping Shi, Mor-Li Hartman, Mary Tavares, Milad Bitar, Hamad Ali, Hossein Arefanian, Sriraman Devarajan, Faisal Al-Refaei, Osama Alsmadi, Jaakko Tuomilehto, Fahd Al-Mulla
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/098e2e965a4242aea304bbf4ccf02e39
Autor:
Rasheeba Nizam, Ebaa Al-Ozairi, Jo Max Goodson, Motesam Melhem, Lena Davidsson, Hessa Alkhandari, Ashraf Al Madhoun, Sara Shamsah, Malak Qaddoumi, Ghazi Alghanim, Nouf Alhasawi, Mohamed Abu-Farha, Jehad Abubaker, Ping Shi, Mor-Li Hartman, Mary Tavares, Milad Bitar, Hamad Ali, Hossein Arefanian, Sriraman Devarajan, Faisal Al-Refaei, Osama Alsmadi, Jaakko Tuomilehto, Fahd Al-Mulla
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Caveolin-1 (CAV1) variants have been suggested to be associated with obesity and related metabolic disorders, but information based on human studies is limited. In the present study, we aimed to investigate the potential association between the CAV1
Externí odkaz:
https://doaj.org/article/9f2c18cab3db4466894fb8fcf7a07d86
Autor:
Ashraf Al Madhoun, Shihab Kochumon, Dania Haddad, Reeby Thomas, Rasheeba Nizam, Lavina Miranda, Sardar Sindhu, Milad S. Bitar, Rasheed Ahmad, Fahd Al-Mulla
Obesity is characterized by chronic low-grade inflammation. Caveolin-1 (CAV1), a structural and functional protein found in adipose tissues (AT), is augmented in obese individuals. We aimed to define the inflammatory mediators that influence CAV1 gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0107750328f753eb7bcce86fd7edeefc