Zobrazeno 1 - 10
of 352
pro vyhledávání: '"Ashraf A Aly"'
Autor:
AbdElAziz A. Nayl, Esmail M. El-Fakharany, Ahmed I. Abd-Elhamid, Wael A. A. Arafa, Ahmed H. Alanazi, Ismail M. Ahmed, Mohamed A. Abdelgawad, Ashraf A. Aly, Stefan Bräse
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract It is imperative to explore new biocompatible drugs with low toxicity for use in medicinal fields such as fighting tumors. Bovine lactoperoxidase (BLPO) stems from the most important enzymes in the bovine whey that provide a proper pattern f
Externí odkaz:
https://doaj.org/article/c8d4042fcf0c462babf30fe7659d66e3
Autor:
Ashraf A Aly, Stefan Bräse, Alaa A. Hassan, Nasr K. Mohamed, Lamiaa E. Abd El-Haleem, Martin Nieger, Nesrin M. Morsy, Elshimaa M. N. Abdelhafez
Publikováno v:
Molecules, Vol 25, Iss 13, p 3089 (2020)
A new series of methyl 2-(2-(4′-[2.2]paracyclophanyl)-hydrazinylidene)-3-substituted-4-oxothiazolidin-5-ylidene)acetates 3a–f were synthesized from the reaction of paracyclophanyl-acylthiosemicarbazides 2a–f with dimethyl acetylenedicarboxylate
Externí odkaz:
https://doaj.org/article/4b57b26bfde943308653d4096fbd462b
Autor:
Asmaa H. Mohamed, Mohammed B. Alshammari, Ashraf A. Aly, Kamal U. Sadek, Akil Ahmad, Eman A. Aziz, Amira F. El-Yazbi, Eman J. El-Agroudy, Marwa E. Abdelaziz
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractIn this article, a new series of 2-((3,5-disubstituted-2-thioxo-imidazol-1-yl)imino)acenaphthylen-1(2H)-ones were synthesized. Imidazole-2-thione with acenaphthylen-one gave a hybrid scaffold that integrated key structural elements essential
Externí odkaz:
https://doaj.org/article/d8620a5fc0cd4a7089a790bc8280f2aa
Autor:
Alaa A. Hassan, Nasr K. Mohamed, Ashraf A. Aly, Mohamed Ramadan, Hesham A. M. Gomaa, Ahmed T. Abdel-Aziz, Bahaa G. M. Youssif, Stefan Bräse, Olaf Fuhr
Publikováno v:
Molecules, Vol 28, Iss 24, p 7951 (2023)
Thiazole and thiazolidinone recur in a wide range of biologically active compounds that reach different targets within the context of tumors and represent a promising starting point to access potential candidates for treating metastatic cancer. There
Externí odkaz:
https://doaj.org/article/7feb057c741149129a88a88a7cb30fee
Autor:
Ashraf A. Aly, Mohammed B. Alshammari, Akil Ahmad, Hesham A. M. Gomaa, Bahaa G. M. Youssif, Stefan Bräse, Mahmoud A. A. Ibrahim, Asmaa H. Mohamed
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 4, Pp 104612- (2023)
In this article, we display on the synthesis and biological evaluation of a new series of thiazolylpyrimidine 3a-l and thiazolidinylpyrimidine derivatives 5a-e. The structures of the new compounds were confirmed by using different spectral techniques
Externí odkaz:
https://doaj.org/article/6f2d3d5650884a28a154186373f67503
Autor:
Mohammed B. Alshammari, Ashraf A. Aly, Bahaa G. M. Youssif, Stefan Bräse, Akil Ahmad, Alan B. Brown, Mahmoud A. A. Ibrahim, Asmaa H. Mohamed
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Thiourea derivatives of uracil were efficiently synthesized via the reaction of 5-aminouracil with isothiocyanates. Then, we prepared uracil-containing thiazoles via condensation of thioureas with diethyl/dimethyl acetylenedicarboxylates. The structu
Externí odkaz:
https://doaj.org/article/083e7d11dc634b0892b7c23158fb3bac
Publikováno v:
Molecules, Vol 28, Iss 4, p 1808 (2023)
This review focuses on some interesting and recent applications of transition metals towards the complexation of thiosemicarbazides, thiocarbohydrazides, and their corresponding carbazones. We started the review with a description of the chosen five
Externí odkaz:
https://doaj.org/article/fe1c871b4de34785acb8e8ad952ff4f1
Autor:
Yaseen A. M. M. Elshaier, Ashraf A. Aly, Mohamed Abdel-Aziz, Hazem M. Fathy, Alan B. Brown, Stefan Bräse, Mohamed Ramadan
Publikováno v:
Molecules, Vol 27, Iss 20, p 7126 (2022)
Synthesis of thiazolidinone based on quinolone moiety was established starting from 4-hydroxyquinol-2-ones. The strategy started with the reaction of ethyl bromoacetate with 4-hydroxyquinoline to give the corresponding ethyl oxoquinolinyl acetates, w
Externí odkaz:
https://doaj.org/article/570488fbb7cb44e0b5d4e34471f5ac5b
Autor:
AbdElAziz A. Nayl, Hamada Mohamed Ibrahim, Kamal M. Dawood, Wael A. A. Arafa, Ahmed I. Abd-Elhamid, Ismail M. Ahmed, Mohamed A. Abdelgawad, Hazim M. Ali, Ibrahim Hotan Alsohaimi, Ashraf A. Aly, Stefan Bräse, Asmaa Kamal Mourad
Publikováno v:
Molecules, Vol 27, Iss 19, p 6369 (2022)
An appropriate and efficient Q-tube-assisted ammonium acetate-mediated protocol for the assembly of the hitherto unreported 5-arylazopyrazolo[3,4-b]pyridines was demonstrated. This methodology comprises the cyclocondensation reaction of 5-amino-2-phe
Externí odkaz:
https://doaj.org/article/1f7372441e8344abb76a280dad447d7d
Autor:
AbdElAziz A. Nayl, Ashraf A. Aly, Wael A. A. Arafa, Ismail M. Ahmed, Ahmed I. Abd-Elhamid, Esmail M. El-Fakharany, Mohamed A. Abdelgawad, Hendawy N. Tawfeek, Stefan Bräse
Publikováno v:
Molecules, Vol 27, Iss 12, p 3716 (2022)
In this review, we focus on some interesting and recent examples of various applications of organic azides such as their intermolecular or intramolecular, under thermal, catalyzed, or noncatalyzed reaction conditions. The aforementioned reactions in
Externí odkaz:
https://doaj.org/article/1ab3d0a2382c4e93a843a0b7b67e408b