Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ashoka A. Maddur"'
Autor:
Ashoka A. Maddur, Breanne H.Y. Gibson, Mary E. Aschenbrenner, Peter Panizzi, Paul E. Bock, Jonathan H. Sheehan, Ingrid M. Verhamme, Jens Meiler, Heather K. Kroh
Publikováno v:
J Biol Chem
In Staphylococcus aureus–caused endocarditis, the pathogen secretes staphylocoagulase (SC), thereby activating human prothrombin (ProT) and evading immune clearance. A previous structural comparison of the SC(1–325) fragment bound to thrombin and
Autor:
Markus Voehler, Ingrid M. Verhamme, Peter Panizzi, Jens Meiler, Paul E. Bock, Ashoka A. Maddur
Publikováno v:
The Journal of Biological Chemistry
The N-terminus of S. aureus staphylocoagulase (SC) triggers activation of host prothrombin (ProT), and the SC·ProT* complex cleaves host fibrinogen (Fbg) to form fibrin (Fbn) deposits, a hallmark of SC-positive endocarditis. The C-terminal domain of
Publikováno v:
Journal of Biological Chemistry. 288:32020-32035
Serpin protein protease inhibitors inactivate their target proteases through a unique mechanism in which a major serpin conformational change, resulting in a 70-A translocation of the protease from its initial reactive center loop docking site to the
Publikováno v:
Insect Biochemistry and Molecular Biology. 35:23-32
Fifteen unique cDNA clones encoding trypsin- or chymotrypsin-like proteins were cloned and characterized from a gut cDNA library derived from Hessian fly [Mayetiola destructor (Say)] larvae. Based on sequence similarities, the cDNAs were sorted into
Publikováno v:
The Journal of biological chemistry. 288(44)
Serpin protein protease inhibitors inactivate their target proteases through a unique mechanism in which a major serpin conformational change, resulting in a 70-Å translocation of the protease from its initial reactive center loop docking site to th
Autor:
Ashoka A. Maddur, Jennifer L. Newell-Caito, Malabika Laha, Guido Tans, Anthony C. Tharp, Hong Xu, Jonathan I. Creamer, Paul E. Bock
Publikováno v:
Journal of Biological Chemistry, 286(44), 38286-38297. American Society for Biochemistry and Molecular Biology, Inc.
Notecarin D (NotD) is a prothrombin (ProT) activator in the venom of the tiger snake, Notechis scutatus, and a factor Xa (FXa) homolog. NotD binds specifically to the FXa binding site expressed on factor V (FV) upon activation to factor Va (FVa) by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede3aaf84c00bef466405c87769b135c
https://cris.maastrichtuniversity.nl/en/publications/9ab45b00-4dd0-4ee7-9c75-989f0f595030
https://cris.maastrichtuniversity.nl/en/publications/9ab45b00-4dd0-4ee7-9c75-989f0f595030
Autor:
Edmund J. Keliher, Filip K. Swirski, Olaf Schneewind, Jose-Luiz Figueiredo, Yoshiko Iwamoto, Ralph Weissleder, Tilman M. Hackeng, Pablo Fuentes-Prior, Matthias Nahrendorf, Paul E. Bock, Mikael J. Pittet, Elena Aikawa, Peter Panizzi, Brett Marinelli, Florian Leuschner, Peter Waterman, Ashoka A. Maddur, Jennifer R. Panizzi, Heather K. Kroh
Publikováno v:
Nature medicine
NATURE MEDICINE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Nature Medicine, 17(9), 1142-U153. Nature Publishing Group
NATURE MEDICINE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Nature Medicine, 17(9), 1142-U153. Nature Publishing Group
Coagulase-positive Staphylococcus aureus (S. aureus) is the major causal pathogen of acute endocarditis, a rapidly progressing, destructive infection of the heart valves. Bacterial colonization occurs at sites of endothelial damage, where, together w
Autor:
Shamanaev A; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN., Ivanov I; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN., Sun MF; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN., Litvak M; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN., Srivastava P; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN., Mohammed BM; Edward A. Doisy Research Center, Department of Biochemistry and Molecular Biology, St. Louis University School of Medicine, St. Louis, MO., Shaban R; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN., Maddur A; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN., Verhamme IM; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN., McCarty OJT; Department of Biomedical Engineering, and.; Division of Hematology and Medical Oncology, Department of Medicine, Oregon Health and Science University, Portland, OR; and., Law RHP; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia., Gailani D; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN.
Publikováno v:
Blood advances [Blood Adv] 2022 May 24; Vol. 6 (10), pp. 3142-3154.
Autor:
Panizzi P; Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL 36849, USA., Krohn-Grimberghe M; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA.; University Heart Center Freiburg, 79106 Freiburg, Germany., Keliher E; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Ye YX; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Grune J; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Frodermann V; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Sun Y; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Muse CG; Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL 36849, USA., Bushey K; Green Mountain Antibodies, Burlington, VT 05401, USA., Iwamoto Y; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., van Leent MMT; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Meerwaldt A; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Toner YC; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Munitz J; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Maier A; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Soultanidis G; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Calcagno C; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Pérez-Medina C; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Centro Nacional de Investigaciones Cardivasculares, 28029 Madrid, Spain., Carlucci G; Bernard and Irene Schwarz Center for Biomedical Imaging, New York University, New York, NY 10016, USA., Riddell KP; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA., Barney S; Department of Clinical Science, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA., Horne G; Department of Clinical Science, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA., Anderson B; Swine Research and Education Center, Department of Animal Sciences, Auburn University, Auburn, AL 36849, USA., Maddur-Appajaiah A; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Verhamme IM; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Bock PE; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Wojtkiewicz GR; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Courties G; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Swirski FK; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Church WR; Green Mountain Antibodies, Burlington, VT 05401, USA., Walz PH; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA., Tillson DM; Department of Clinical Science, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA., Mulder WJM; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, 5612 AZ Eindhoven, Netherlands., Nahrendorf M; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA. mnahrendorf@mgh.harvard.edu.; Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.; Department of Internal Medicine I, University Hospital Würzburg, 97080 Würzburg, Germany.
Publikováno v:
Science translational medicine [Sci Transl Med] 2020 Nov 04; Vol. 12 (568).