Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Ashok Purandare"'
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Supplementary Table 2 from Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression
Autor: Susan Wee, Tai Wong, Craig Fairchild, Petra Ross-Macdonald, Ashok Purandare, Liang Schweizer, Russell Peterson, Kathy Johnston, Ming Lei, Jian Cao, Heshani Desilva, Stefan Kirov, Ryan Lenhart
Microarray data for the 5 probe sets that show differential responses to JQ1 treatment. Shown are the Affymetrix RMA anti-log values of probe intensity with each treatment, together with the fold change in signal from JQ1 treatment and the JQ1 concen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7facb10562e6d7eeda3f57ecf51d390b
https://doi.org/10.1158/1535-7163.22501642
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Data from Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression
Autor: Susan Wee, Tai Wong, Craig Fairchild, Petra Ross-Macdonald, Ashok Purandare, Liang Schweizer, Russell Peterson, Kathy Johnston, Ming Lei, Jian Cao, Heshani Desilva, Stefan Kirov, Ryan Lenhart
The BET (bromodomain and extra-terminal) proteins bind acetylated histones and recruit protein complexes to promote transcription elongation. In hematologic cancers, BET proteins have been shown to regulate expression of MYC and other genes that are
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e13d258e5640d006714c350f047602ca
https://doi.org/10.1158/1535-7163.c.6536854.v1
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5
Supplementary Figures 1 through 8 from Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression
Autor: Susan Wee, Tai Wong, Craig Fairchild, Petra Ross-Macdonald, Ashok Purandare, Liang Schweizer, Russell Peterson, Kathy Johnston, Ming Lei, Jian Cao, Heshani Desilva, Stefan Kirov, Ryan Lenhart
Figure S1. Potency of I-BET762 in inhibition of proliferation of lung tumor cell lines. Lineage of lung cell lines is as indicated. Figure S2. Dose response curves of JQ1 in cell proliferation assays. Shown are examples of lung tumor cell lines with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f48394b5ceac603e4b0587b11ae1b320
https://doi.org/10.1158/1535-7163.22501648.v1
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6
Abstract 4004: Targeting drug-resistant acute myeloid leukemia (AML) cells using novel casein kinase II (CK2) inhibitor
Autor: Koby Duke, Katherine Mercer, Rajesh Rajaiah, Muhammad Daniyal, Yi Qiu, Ashok Purandare, Yasin Uzun, Lijun Zhang, Morgann Klink, Chandrika Gowda
Publikováno v: Cancer Research. 83:4004-4004
Introduction: Protein Kinase CK2 level and activity are high in Acute Myeloid Leukemia (AML) stem cells. Genetic inhibition of CK2 promotes apoptosis and shows synergistic cytotoxic activity with cytotoxic therapy. Here we report the anti-leukemia ef
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c459e83acf52c91c2596c19f08d63ce5
https://doi.org/10.1158/1538-7445.am2023-4004
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Molecular Recognition and Reactivity of Ruthenium(II) Bipyridine Barbituric Acid Guests in the Presence of Complementary Hosts: Ruthenium(II) Promoted Enolization of Barbituric Acids in Guest−Host Complexes
Autor: Yeung-gyo K. Shin, Stephan S. Isied, Spencer Knapp, Ashok Purandare, Teen Chin, Zhinong Gao, Isabelle Lelouche
Publikováno v: Journal of the American Chemical Society. 119:12849-12858
The binding of the host H1 (N,N‘-bis(6-pivalamidopyrid-2-yl)-3,5-pyridinedicarboxamide) to three different ruthenium polypyridine complexes with an attached barbituric acid and barbital moieties (RuG1, RuG2, RuG3) (where G1 = 5-[4-(4‘-methyl)-2,2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::126584bac17a52068af13495fe212107
https://doi.org/10.1021/ja971481y
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