Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ashok P. Bidwai"'
Drosophila Protein Kinase CK2: Genetics, Regulatory Complexity and Emerging Roles during Development
Publikováno v:
Pharmaceuticals, Vol 10, Iss 1, p 4 (2016)
CK2 is a Ser/Thr protein kinase that is highly conserved amongst all eukaryotes. It is a well-known oncogenic kinase that regulates vital cell autonomous functions and animal development. Genetic studies in the fruit fly Drosophila are providing uniq
Externí odkaz:
https://doaj.org/article/c592295583dd4e3a9aebf5789785f54a
Autor:
Ashok P. Bidwai, Lucas M. Jozwick
Publikováno v:
Molecular and Cellular Biochemistry. 478:781-790
Across metazoans, the effects of Notch signaling are mediated via the Enhancer of Split (E(spl)/HES) basic Helix-Loop-Helix-Orange (bHLH-O) repressors. Although conserved, sequence diversity is, in large part, restricted to the C-terminal domain (CtD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f68a3771fe984e49450a50e5992674
https://doi.org/10.1007/s11010-022-04539-5
https://doi.org/10.1007/s11010-022-04539-5
Autor:
Lucas M, Jozwick, Ashok P, Bidwai
Publikováno v:
Molecular and cellular biochemistry.
Across metazoan animals, the effects of Notch signaling are mediated via the Enhancer of Split (E(spl)/HES) basic Helix-Loop-Helix-Orange (bHLH-O) repressors. Although these repressors are generally conserved, their sequence diversity is, in large pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ed23ae9a9f6aad96681209dc0f9369f
https://pubmed.ncbi.nlm.nih.gov/36087252
https://pubmed.ncbi.nlm.nih.gov/36087252
Drosophilaretinal patterning requires the expression of Atonal (Ato) through coordinated regulation of 5’ and 3’ enhancer modules.ato-3’directs initial expression of Ato which then directs autoregulation via5’-ato. Notch (N) signaling also re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd82c333421b5cbb27fea6bfca0bc4e
https://doi.org/10.1101/678169
https://doi.org/10.1101/678169
Autor:
Ashok P. Bidwai, Adam T. Majot
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186439 (2017)
PLoS ONE
PLoS ONE
Drosophila atonal (ato) is required for the specification of founding R8 photoreceptors during retinal development. ato is regulated via dual eye-specific enhancers; ato-3’ is subject to initial induction whereas 5’-ato facilitates Notch-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be572e5cf83450276eb7d426c4f17363
http://europepmc.org/articles/PMC5643056?pdf=render
http://europepmc.org/articles/PMC5643056?pdf=render
Drosophila Protein Kinase CK2: Genetics, Regulatory Complexity and Emerging Roles during Development
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 10, Iss 1, p 4 (2016)
Pharmaceuticals, Vol 10, Iss 1, p 4 (2016)
CK2 is a Ser/Thr protein kinase that is highly conserved amongst all eukaryotes. It is a well-known oncogenic kinase that regulates vital cell autonomous functions and animal development. Genetic studies in the fruit fly Drosophila are providing uniq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf596b9c9691ecbf243f76920cdea92
http://europepmc.org/articles/PMC5374408
http://europepmc.org/articles/PMC5374408
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159508 (2016)
PLoS ONE
PLoS ONE
The specification of patterned R8 photoreceptors at the onset of eye development depends on timely inhibition of Atonal (Ato) by the Enhancer of split (E(spl) repressors. Repression of Ato by E(spl)-M8 requires the kinase CK2 and is inhibited by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050ce67f68aaa19139a3d40771b76c58
http://europepmc.org/articles/PMC4948772?pdf=render
http://europepmc.org/articles/PMC4948772?pdf=render
Publikováno v:
genesis. 47:647-658
Repression by E(spl)M8 during inhibitory Notch (N) signaling (lateral inhibition) is regulated, in part, by protein kinase CK2, but the involvement of a phosphatase has been unclear. The studies we report here employ Tik, a unique dominant-negative (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7cfba6c5bb80d8db7191716bc234f03
https://doi.org/10.1002/dvg.20543
https://doi.org/10.1002/dvg.20543
Autor:
Ezgi Kunttas-Tatli, Pallavi P. Kuntamalla, Umesh C. Karandikar, Clifton P. Bishop, Ashok P. Bidwai
Publikováno v:
Molecular and Cellular Biochemistry. 323:49-60
CK2 is a Ser/Thr protein kinase essential for animal development. Although null alleles for CK2 are available in the mouse and Drosophila models, they are lethal when homozygous, thus necessitating conditional alleles for analysis of its developmenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d603a06fbfbd291c581922fa839f27
https://doi.org/10.1007/s11010-008-9963-6
https://doi.org/10.1007/s11010-008-9963-6
Autor:
Ze'ev Paroush, Ravi Allada, Ashok P. Bidwai, Clifton P. Bishop, Bhaskar Kahali, Regina L. Trott
Publikováno v:
Biochemical and Biophysical Research Communications. 373:637-642
Hairy is a repressor that regulates bristle patterning, and its loss elicits ectopic bristles (neural hyperplasia). However, it has remained unknown whether Hairy is regulated by phosphorylation. We describe here the interaction of protein kinase CK2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49ace64df7ed11a970e933e04d84a2d
https://doi.org/10.1016/j.bbrc.2008.06.084
https://doi.org/10.1016/j.bbrc.2008.06.084