Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Ashok K. Mehta"'
Publikováno v:
Brain Research. 1165:15-20
In the present study, we investigated the co-localization pattern of the delta subunit with other subunits of GABA(A) receptors in the rat brain using immunoprecipitation and Western blotting techniques. Furthermore, we investigated whether low conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c17ff5804da541a1741a662abc3d41c
https://doi.org/10.1016/j.brainres.2007.06.051
https://doi.org/10.1016/j.brainres.2007.06.051
Autor:
Ashok K. Mehta, Maneesh Gupta, Lawrence P. Carter, K. Michael Gibson, Maharaj K. Ticku, Georgianna G. Gould
Publikováno v:
Molecular Genetics and Metabolism. 88:86-89
We investigated whether succinate semialdehyde dehydrogenase deficiency alters γ-hydroxybutyric acid (GHB) receptor characteristics due to elevation of GHB levels in the mouse brain. The membrane homogenate binding and quantitative autoradiography u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e73403b3f7b751f7d00570e95a0175
https://doi.org/10.1016/j.ymgme.2005.11.012
https://doi.org/10.1016/j.ymgme.2005.11.012
Autor:
Lawrence P. Carter, Weibin Chen, Huifang Wu, Ashok K. Mehta, R. Jason Hernandez, Maharaj K. Ticku, Andrew Coop, Wouter Koek, Charles P. France
Publikováno v:
Drug and Alcohol Dependence. 78:91-99
Gamma-hydroxybutyrate (GHB), a metabolite of GABA, is a drug of abuse and a therapeutic. The illicit use of GHB precursors and analogs reportedly has increased worldwide. Gamma-hydroxyvaleric (GHV) is a 4-methyl-substituted analog of GHB that reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e8106e751d5aff449a323dea5945f8
https://doi.org/10.1016/j.drugalcdep.2004.10.002
https://doi.org/10.1016/j.drugalcdep.2004.10.002
Autor:
Ashok K. Mehta
Publikováno v:
South Asian Survey. 11:177-192
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8fb1312e83745232d2de07c1bdb0b06
https://doi.org/10.1177/097152310401100202
https://doi.org/10.1177/097152310401100202
Publikováno v:
Brain Research. 979:51-56
(2E)-(5-Hydroxy-5,7,8,9-tetrahydro-6H-benzo[a][7]annulen-6-ylidene) ethanoic acid (NCS-382) is an antagonist for gamma-hydroxybutyric acid (GHB) at GHB receptor sites. Advantages of using [(3)H]NCS-382 over [(3)H]GHB in radioligand binding studies ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b5d3d05198a898f522333768c763f6
https://doi.org/10.1016/s0006-8993(03)02865-8
https://doi.org/10.1016/s0006-8993(03)02865-8
Autor:
Ashok K. Mehta, Maharaj K. Ticku
Publikováno v:
Current Protocols in Pharmacology
This protocol describes an in vitro assay for characterization of the picrotoxin site of GABA(A) receptors in rat brain membranes using various radioligands. Methods and representative data for Scatchard analysis (Kd, Bmax determination), association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256ce0615d57c988ef20ce6432b87bfe
https://pubmed.ncbi.nlm.nih.gov/24510752
https://pubmed.ncbi.nlm.nih.gov/24510752
Autor:
Ashok K. Mehta, Maharaj K. Ticku
Publikováno v:
Neuropharmacology. 40:668-675
Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) inhibited the binding of [(3)H]flunitrazepam (2 nM), [(3)H]muscimol (5 nM) and 4 nM [(35)S]t-butylbicyclophosphorothionate [(35)S]TBPS in the rat cerebellum as well as cerebral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad51ef99294fd993e5ae8e753e0dbbdb
https://doi.org/10.1016/s0028-3908(00)00200-8
https://doi.org/10.1016/s0028-3908(00)00200-8
Publikováno v:
The Journal of Comparative Neurology. 413:535-548
A novel anti-beta(3) subunit-specific GABA(A) receptor (GABA(A)R) antibody has been prepared by immunizing a rabbit with a bacterial fusion protein of the large intracellular loop of the beta(3) subunit. The antiserum immunoprecipitated the solubiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efdf100d2b647a671c894bae194fd225
https://doi.org/10.1002/(sici)1096-9861(19991101)413:4<535::aid-cne4>3.0.co
https://doi.org/10.1002/(sici)1096-9861(19991101)413:4<535::aid-cne4>3.0.co
Autor:
Maharaj K. Ticku, Ashok K. Mehta
Publikováno v:
Brain Research. 832:164-167
Chronic administration of Nω-nitro- l -arginine methyl ester ( l -NAME), an inhibitor of nitric oxide synthase, diminished the ability of 5α-pregnan-3α-ol-20-one, a neurosteroid, to potentiate the [ 3 H ]muscimol (5 nM) binding in the rat hippocam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add21436ecf0668f63aaededb6d6770c
https://doi.org/10.1016/s0006-8993(99)01410-9
https://doi.org/10.1016/s0006-8993(99)01410-9
Autor:
Ashok K. Mehta, Maharaj K. Ticku
Publikováno v:
Molecular Brain Research. 67:194-199
The anti-alpha1 antibody elicited higher immunoprecipitation (%) values of the [3H]flunitrazepam and [3H]muscimol binding activity in the rat cerebellum vs. cerebral cortex, whereas immunoprecipitation values for [3H]Ro 15-4513 and [3H]zolpidem were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5251581ce2505ebd1522e96313c40ccf
https://doi.org/10.1016/s0169-328x(99)00020-0
https://doi.org/10.1016/s0169-328x(99)00020-0