Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ashok G. Chaudhary"'
Autor:
George A. Orr, Srinivasa K. Rao, Susan Band Horwitz, David G. I. Kingston, Ashok G. Chaudhary
Publikováno v:
Journal of Biological Chemistry. 270:20235-20238
Photoaffinity labeling methods are being used to define the molecular contacts between taxol and its target protein, tubulin. Our laboratory has demonstrated previously that [3H]3′-(p-azidobenzamido)taxol photolabels the N-terminal 31 amino acids o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e617935b1244874f5834adf1a60b2cb
https://doi.org/10.1074/jbc.270.35.20235
https://doi.org/10.1074/jbc.270.35.20235
Publikováno v:
Tetrahedron Letters. 35:6843-6846
4-Deacetoxypaclitaxel ( 9 ) has been prepared in seven steps from paclitaxel (Taxol ® ). It is significantly less active than paclitaxel in tubulin-assembly and cytotoxicity bioassays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97794edd8e3ae21290da674880a57c51
https://doi.org/10.1016/0040-4039(94)85019-4
https://doi.org/10.1016/0040-4039(94)85019-4
Autor:
John M. Rimoldi, Ernest Hamel, David G. L. Kingston, Gamini Samaranayake, Ashok G. Chaudhary, Surinder Grover
Publikováno v:
Journal of Natural Products. 56:1313-1330
The 7-substituted taxol analogues 7, 19, 27, and 32 have been prepared as potential photoaffinity-labeled derivatives for studies of the nature of the binding site of taxol on polymerized tubulin. The analogue 32 has been prepared in both deuterium-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9938ed31717bfec2b42e0b6ad9b8e94
https://doi.org/10.1021/np50098a016
https://doi.org/10.1021/np50098a016
Publikováno v:
Tetrahedron Letters. 34:4921-4924
10-Deacetoxytaxol (9) and 10-deoxytaxotere (10) have been prepared from 10-deacetylbaccatin III by attachment of the C-13 side-chain and deoxygenation. 10-Deacetoxytaxol is comparable to taxol in its cytotoxicity to P-388 cells, but 10-deoxytaxotere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88c774647a537cc4eab702078ca9d081
https://doi.org/10.1016/s0040-4039(00)74046-9
https://doi.org/10.1016/s0040-4039(00)74046-9
Autor:
M. Shah, Malay Ghosh, S. S. Bari, Ajay K. Bose, Bimal K. Banik, Sarder N. Newaz, Ashok G. Chaudhary, Khaled J. Barakat, Maghar S. Manhas, Vegesna S. Raju
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f9e53512fb022645aa473e97e6cb30d
https://doi.org/10.1002/chin.199222081
https://doi.org/10.1002/chin.199222081
Publikováno v:
ChemInform. 24
The condensation of ethyl phenylacetate or ethyl β-hydroxybutyrate with Schiff bases in presence of an excess of lithium diisopropylamide or lithium hexamethyldisilazide leads to unsaturated amines instead of the expected β-lactams
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fff5d9d4d99906345ea8bef3905ef50
https://doi.org/10.1002/chin.199346158
https://doi.org/10.1002/chin.199346158
Publikováno v:
ChemInform. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d1f79ccd40e1c05eb0d33ec256d14b3
https://doi.org/10.1002/chin.199345304
https://doi.org/10.1002/chin.199345304
Autor:
Ashok G. Chaudhary, A. A. L. Gunatilaka, Milind M. Gharpure, S. Grover, Chii M. Lin, Ernest Hamel, John M. Rimoldi, David G. I. Kingston, Mahendra D. Chordia
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b749beed97af250fff993bd2c94e389e
https://doi.org/10.1002/chin.199437190
https://doi.org/10.1002/chin.199437190
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e995282e1240f9ceaae588f601cb218
https://doi.org/10.1002/chin.199446211
https://doi.org/10.1002/chin.199446211
Publikováno v:
ChemInform. 26
4-Deacetoxypaclitaxel ( 9 ) has been prepared in seven steps from paclitaxel (Taxol ® ). It is significantly less active than paclitaxel in tubulin-assembly and cytotoxicity bioassays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cde2c9efb10343a210a774590849c573
https://doi.org/10.1002/chin.199507206
https://doi.org/10.1002/chin.199507206