Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ashna Alladin"'
Autor:
Ksenija Radic Shechter, Eleni Kafkia, Katharina Zirngibl, Sylwia Gawrzak, Ashna Alladin, Daniel Machado, Christian Lüchtenborg, Daniel C Sévin, Britta Brügger, Kiran R Patil, Martin Jechlinger
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 10, Pp n/a-n/a (2021)
Abstract Tumor relapse from treatment‐resistant cells (minimal residual disease, MRD) underlies most breast cancer‐related deaths. Yet, the molecular characteristics defining their malignancy have largely remained elusive. Here, we integrated mul
Externí odkaz:
https://doaj.org/article/c0276c0d71bf4b688df33f54bc4ee1f4
Autor:
Ashna Alladin, Lucas Chaible, Lucia Garcia del Valle, Reither Sabine, Monika Loeschinger, Malte Wachsmuth, Jean-Karim Hériché, Christian Tischer, Martin Jechlinger
Publikováno v:
eLife, Vol 9 (2020)
Cancer clone evolution takes place within tissue ecosystem habitats. But, how exactly tumors arise from a few malignant cells within an intact epithelium is a central, yet unanswered question. This is mainly due to the inaccessibility of this process
Externí odkaz:
https://doaj.org/article/5ed910f33e864e568756f91c9a47e7a6
Autor:
Richard M. Terek, Qian Chen, Jesse Hart, Ross Taliano, Jose Ramirez, Ashna Alladin, Jason T. Machan, Hongchuan Yu, Yupeng Chen, Xiaojuan Sun
Chondrosarcoma is a highly aggressive primary malignant bone tumor mostly occurring in adults. There are no effective systemic treatments, and patients with this disease have poor survival. miR-181a is an oncomiR that is overexpressed in high-grade c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ac43948ce3883ae4d488bbe5b8aa65
https://doi.org/10.1158/1535-7163.c.6538324.v1
https://doi.org/10.1158/1535-7163.c.6538324.v1
Autor:
Richard M. Terek, Qian Chen, Jesse Hart, Ross Taliano, Jose Ramirez, Ashna Alladin, Jason T. Machan, Hongchuan Yu, Yupeng Chen, Xiaojuan Sun
Lung metastatic burden quantified as number of nodules per lung and area of nodules as a percent of total lung area.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb38a50e9caedb4c526fe2e8a4c83389
https://doi.org/10.1158/1535-7163.22506205.v1
https://doi.org/10.1158/1535-7163.22506205.v1
Autor:
Richard M. Terek, Jason T. Machan, Ashna Alladin, Jesse Hart, Xiaojuan Sun, Hongchuan Yu, Ross Taliano, Yupeng Chen, Jose M. Ramirez, Qian Chen
Publikováno v:
Mol Cancer Ther
Chondrosarcoma is a highly aggressive primary malignant bone tumor mostly occurring in adults. There are no effective systemic treatments, and patients with this disease have poor survival. miR-181a is an oncomiR that is overexpressed in high-grade c
Autor:
Reither Sabine, Martin Jechlinger, Monika Loeschinger, Jean-Karim Hériché, Lucia Garcia del Valle, Malte Wachsmuth, Ashna Alladin, Lucas M. Chaible, Christian Tischer
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Cancer clone evolution takes place within tissue ecosystem habitats. But, how exactly tumors arise from a few malignant cells within an intact epithelium is a central, yet unanswered question. This is mainly due to the inaccessibility of this process
Autor:
Ashna Alladin, Jean-Karim Hériché, Reither Sabine, Malte Wachsmuth, Lucia Garcia del Valle, Martin Jechlinger, Lucas M. Chaible, Monika Loeschinger, Christian Tischer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ec539d1977c86889556712fba015424
https://doi.org/10.7554/elife.54066.sa2
https://doi.org/10.7554/elife.54066.sa2
Autor:
Christian Lüchtenborg, Daniel Machado, Britta Brügger, Katharina Zirngibl, Ksenija Radic Shechter, Sylwia Gawrzak, Kiran Raosaheb Patil, Martin Jechlinger, Daniel C. Sévin, Eleni Kafkia, Ashna Alladin
Tumor relapse is responsible for most breast cancer related deaths1,2. The disease recurrence stems from treatment refractory cancer cells that persist as minimal residual disease (MRD) for years following initial therapy3. Yet, the molecular charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7386edb41599f84e0b3287d5501464b6
Publikováno v:
Biochemistry. 57:1108-1118
PIF1 family helicases are conserved from bacteria to man. With the exception of the well-studied yeast PIF1 helicases (e.g., ScPif1 and ScRrm3), however, very little is known about how these enzymes help maintain genome stability. Indeed, we lack a b
Autor:
Ashna Alladin, Martin Jechlinger
Publikováno v:
Current Opinion in Systems Biology. 6:74-79
Mouse models have been an invaluable tool to systematically study tumour progression upon expression of an oncogene or knockdown of tumour suppressors in an immune-proficient microenvironment. Today, tractable genetically engineered mouse models (GEM