'In-Format' screening of a novel bispecific antibody format reveals significant potency improvements relative to unformatted molecules.

Autor: Scott MJ; a Biopharm Discovery, GlaxoSmithKline , Stevenage , UK., Lee JA; a Biopharm Discovery, GlaxoSmithKline , Stevenage , UK., Wake MS; a Biopharm Discovery, GlaxoSmithKline , Stevenage , UK., Batt KV; a Biopharm Discovery, GlaxoSmithKline , Stevenage , UK., Wattam TA; a Biopharm Discovery, GlaxoSmithKline , Stevenage , UK., Hiles ID; a Biopharm Discovery, GlaxoSmithKline , Stevenage , UK., Batuwangala TD; a Biopharm Discovery, GlaxoSmithKline , Stevenage , UK., Ashman CI; a Biopharm Discovery, GlaxoSmithKline , Stevenage , UK., Steward M; a Biopharm Discovery, GlaxoSmithKline , Stevenage , UK.

Publikováno v: MAbs [MAbs] 2017 Jan; Vol. 9 (1), pp. 85-93. Date of Electronic Publication: 2016 Oct 27.