Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ashlyn T. Young"'
Autor:
Kimberly Nellenbach, Michael A. Daniele, Ashlyn T. Young, Frances S. Ligler, Colleen A. Roosa, Ashley C. Brown, Ismaeel Muhamed
Publikováno v:
Colloids Surf B Biointerfaces
Chronic wounds can occur when the healing process is disrupted and the wound remains in a prolonged inflammatory stage that leads to severe tissue damage and poor healing outcomes. Clinically used treatments, such as high density, FDA-approved fibrin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f779c8500a6ee1f771fc3ca47959ba3e
https://europepmc.org/articles/PMC8217261/
https://europepmc.org/articles/PMC8217261/
Publikováno v:
ACS Sensors. 4:1454-1464
Microphysiological systems replicate human organ function and are promising technologies for discovery of translatable biomarkers, pharmaceuticals, and regenerative therapies. Because microphysiological systems require complex microscale anatomical s
Publikováno v:
Proc IEEE Sens
Herein, a 60-electrode array is fabricated down the length of a microchamber for analysis of a microphysiological system. The electrode array is fabricated by standard photolithographic, metallization, and etching techniques. Permutations of 2-wire i
Publikováno v:
Macromol Biosci
Synthetically-modified proteins, such as gelatin methacryloyl (GelMA), a.k.a. gelatin methacrylate or gelatin methacrylamide, are growing in popularity for bioprinting and biofabrication. GelMA is a photocurable macromer that can rapidly form hydroge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb16bba203dc52374b0a8bf67a604b0
https://europepmc.org/articles/PMC7738368/
https://europepmc.org/articles/PMC7738368/
Photoinduced reconfiguration to control the protein-binding affinity of azobenzene-cyclized peptides
Autor:
Michael A. Daniele, Lewis A Gaffney, Stefano Menegatti, Ashlyn T. Young, Denis Fourches, Raphael Prodromou, Donald O. Freytes, Kevin Day, John D. Schneible, George Van Den Driessche, Vladimir A. Pozdin
Publikováno v:
J Mater Chem B
Journal of Materials Chemistry B
Journal of Materials Chemistry B
The impact of next-generation biorecognition elements (ligands) will be determined by the ability to remotely control their binding activity for a target biomolecule in complex environments. Compared to conventional mechanisms for regulating binding
Publikováno v:
Pharm Res
PURPOSE: This study aimed to develop a hydrogel system for treating aggressive triple negative breast cancer (TNBC) via kinetically-controlled delivery of the synergistic drug pair doxorubicin (DOX) and gemcitabine (GEM). A 2D assay was adopted to ev
Autor:
Nanfei He, Erik E. Santiso, Michael A. Daniele, Srivatsan Ramesh, Radina L. Lilova, Jean Marie Dubnansky, Clay E. Dowdey, John D. Schneible, Stefano Menegatti, Wei Gao, Ashlyn T. Young, Kaihang Shi
Publikováno v:
J Mater Chem B
The scheduled delivery of synergistic drug combinations is increasingly recognized as highly effective against advanced solid tumors. Of particular interest are composite systems that release a sequence of drugs with defined kinetics and molar ratios
Autor:
Rebecca Oberley, Michael A. Daniele, James D. Crapo, Tomoki Fukuyama, Wolfgang Bäumer, Ashlyn T. Young, Kelsey Stover
Publikováno v:
Arch Dermatol Res
In this study, we topically administered two antioxidant compounds, the manganese-porphyrin-derivatives BMX-001 and BMX-010, in a mouse model of allergic dermatitis and compared the efficacy for reduction of itch and inflammation. In vitro effects of
Autor:
Teng Su, Hong Ma, Justin Chen, Ke Cheng, Ashlyn T. Young, Li Qiao, Jiandong Liu, Frances S. Ligler, Li Qian, Jhon Cores, Deliang Shen, Thomas G. Caranasos, Shiqi Hu, Hongxia Liang, Zhenhua Li, Qi Yin, Brianna N. Frame, Phuong-Uyen Dinh, Yevgeny Brudno, Tyler A. Allen, Ke Huang
Cardiovascular disease is the leading cause of mortality worldwide. While reperfusion therapy is vital for patient survival post-heart attack, it also causes further tissue injury, known as myocardial ischemia/reperfusion (I/R) injury in clinical pra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a94646bcc8abfae9a270ee41952799
https://europepmc.org/articles/PMC7111457/
https://europepmc.org/articles/PMC7111457/
Autor:
David A. Stenger, Ashlyn T. Young, Paul T. Charles, Jawad Naciri, Ian D. Giles, Scott A. Trammell, Michael A. Daniele, Jonathan D. Yuen, Vladimir A. Pozdin, Brendan L. Turner
Publikováno v:
Dyes and Pigments. 174:108014
We report the synthesis and characterization of highly air and temperature stable, solution-processed, n-type organic semiconductors: a perylene-diimide monomer and a perylene-diimide-based pendant polymer. When integrated into a transistor structure