Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ashly Hindle"'
Autor:
P. Hemachandra Reddy, Sudhir Kshirsagar, Chhanda Bose, Jangampalli Adi Pradeepkiran, Ashly Hindle, Sharda P. Singh, Arubala P. Reddy, Javaria Baig
Publikováno v:
Cells, Vol 13, Iss 2, p 145 (2024)
The authors wish to make the following changes to their paper [...]
Externí odkaz:
https://doaj.org/article/ee8eb0af8c074c479aae416ccc9fb152
Publikováno v:
Antioxidants, Vol 12, Iss 11, p 1921 (2023)
There is accumulating evidence that vitamin A (VA) deficiency contributes to the pathogenesis and progression of Alzheimer’s disease (AD). All-trans retinoic acid (ATRA), a metabolite of VA in the brain, serves distinct roles in the human hippocamp
Externí odkaz:
https://doaj.org/article/8a6004764e084bd48e060694fd6b1e5d
Autor:
P. Hemachandra Reddy, Sudhir Kshirsagar, Chhanda Bose, Jangampalli Adi Pradeepkiran, Ashly Hindle, Sharda P. Singh, Arubala P. Reddy, Javaria Baig
Publikováno v:
Cells, Vol 12, Iss 12, p 1646 (2023)
RalBP1 (Rlip) is a stress-activated protein that is believed to play a large role in aging and neurodegenerative diseases such as Alzheimer’s disease (AD) and other tauopathies. The purpose of our study was to understand the role of Rlip in mutant
Externí odkaz:
https://doaj.org/article/a5b921244d754b2fbb951a31de1ca2ac
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 149, Iss , Pp 112918- (2022)
Healthy mitochondria are essential for functional bioenergetics, calcium signaling, and balanced redox homeostasis. Dysfunctional mitochondria are a central aspect of aging and neurodegenerative diseases such as Alzheimer’s disease (AD). The format
Externí odkaz:
https://doaj.org/article/21a3466a31f64e898229f33ba9ed03fe
Autor:
Sudhir Kshirsagar, Rainier Vladlen Alvir, Jangampalli Adi Pradeepkiran, Ashly Hindle, Murali Vijayan, Bhagavathi Ramasubramaniam, Subodh Kumar, Arubala P. Reddy, P. Hemachandra Reddy
Publikováno v:
Cells, Vol 11, Iss 17, p 2660 (2022)
In the current study, for the first time, we study mitophagy enhancer urolithin A and a combination of urolithin A+green tea extract EGCG against human Aβ peptide-induced mitochondrial and synaptic, dendritic, inflammatory toxicities and behavioral
Externí odkaz:
https://doaj.org/article/a7b26806e724446189a37e98d8c921a3
Autor:
Sudhir Kshirsagar, Rainier Vladlen Alvir, Ashly Hindle, Subodh Kumar, Murali Vijayan, Jangampalli Adi Pradeepkiran, Arubala P. Reddy, Bhagavathi Ramasubramanian, P. Hemachandra Reddy
Publikováno v:
Cells, Vol 11, Iss 4, p 733 (2022)
The purpose of our study is to investigate early cellular, molecular, morphological and behavioral changes in humanized amyloid-beta-knock-in (hAbKI) mice. Using seven-month-old homozygous hAbKI mice, we studied behavioral phenotype parameters, inclu
Externí odkaz:
https://doaj.org/article/55d6ac4f0ab7434e91eef7597b7e6526
Autor:
Sanjay Awasthi, Ashly Hindle, Neha A. Sawant, Mathew George, Murali Vijayan, Sudhir Kshirsagar, Hallie Morton, Lloyd E. Bunquin, Philip T. Palade, J. Josh Lawrence, Hafiz Khan, Chhanda Bose, P. Hemachandra Reddy, Sharda P. Singh
Publikováno v:
Cells, Vol 10, Iss 11, p 3113 (2021)
The purpose of our study is to understand the role of the RALBP1 gene in oxidative stress (OS), mitochondrial dysfunction and cognition in Alzheimer’s disease (AD) pathogenesis. The RALPB1 gene encodes the 76 kDa protein RLIP76 (Rlip). Rlip functio
Externí odkaz:
https://doaj.org/article/e190e49133eb4f918fe34b7c91dd8f50
Publikováno v:
Journal of Community Hospital Internal Medicine Perspectives. 12:89-94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffba33f730ccdee869634c39c3dd4e71
https://doi.org/10.55729/2000-9666.1090
https://doi.org/10.55729/2000-9666.1090
Autor:
C. Patrick Reynolds, Timothy J. Triche, Daryl C. Drummond, Jonathan B. Fitzgerald, Winford Ko, Ashly Hindle, Riza E. Cruz, Ruben I. Calderon, Michael M. Song, Connor P. Hall, Nancy Paz, Joo-Sang Lee, Monish R. Makena, Jing Wang, Min H. Kang
Supplementary Figure 4: Inverse correlation between sensitivity to DNA damaging agents and SLFN11 expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b21ae371c0c68ae9097ecb6dd31713
https://doi.org/10.1158/1078-0432.22460978
https://doi.org/10.1158/1078-0432.22460978
Autor:
C. Patrick Reynolds, Timothy J. Triche, Daryl C. Drummond, Jonathan B. Fitzgerald, Winford Ko, Ashly Hindle, Riza E. Cruz, Ruben I. Calderon, Michael M. Song, Connor P. Hall, Nancy Paz, Joo-Sang Lee, Monish R. Makena, Jing Wang, Min H. Kang
Purpose: To determine the pharmacokinetics and the antitumor activity in pediatric cancer models of MM-398, a nanoliposomal irinotecan (nal-IRI).Experimental Design: Mouse plasma and tissue pharmacokinetics of nal-IRI and the current clinical formula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08cdeac6283876d09e8ace69f4c91b37
https://doi.org/10.1158/1078-0432.c.6524660
https://doi.org/10.1158/1078-0432.c.6524660