Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ashley Sunderland"'
Autor:
Marlous Hall, Jennifer Williams, Fiona Errington-Mais, Tereza Andreou, Rebecca J Brownlie, Robert J Salmond, Mihaela Lorger, Scott Gregory, Fiona James, Christopher Fife, Ashley Sunderland, Clive McKimmie, Samuel Heaton, Zarnaz Hadi, David R Westhead, Alexander Davie, Amber Emmett
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 11 (2024)
Background Brain metastases (BrM) affect up to 60% of patients with metastatic melanoma and are associated with poor prognosis. While combined immune checkpoint blockade of programmed death-1 (PD-1) and cytotoxic T-lymphocyte-associated protein 4 (CT
Externí odkaz:
https://doaj.org/article/3bcea94ec8a94258978f49f726d9e04e
Autor:
Ashley Sunderland, Jennifer Williams, Tereza Andreou, Nora Rippaus, Christopher Fife, Fiona James, Yolanda Dyah Kartika, Valerie Speirs, Ian Carr, Alastair Droop, Mihaela Lorger
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Exit of quiescent disseminated cancer cells from dormancy is thought to be responsible for metastatic relapse and a better understanding of dormancy could pave the way for novel therapeutic approaches. We used an in vivo model of triple negative brea
Externí odkaz:
https://doaj.org/article/edd0e15041a74a878fd5719f0821bcfc
Hematopoietic Stem Cell Gene Therapy for Brain Metastases Using Myeloid Cell–Specific Gene Promoters
Autor:
Ryan K. Mathew, Ashley Sunderland, Alastair Droop, Christopher Fife, Jennifer Williams, Nora Rippaus, Stephanie Cherqui, Tereza Andreou, Teklu Egnuni, Yolanda D Kartika, David Taggart, Sheri L. Holmen, Krzysztof Wronski, Mihaela Lorger, Rebecca J Brownlie
Publikováno v:
Journal of the National Cancer Institute, vol 112, iss 6
JNCI Journal of the National Cancer Institute
JNCI Journal of the National Cancer Institute
Background Brain metastases (BrM) develop in 20–40% of cancer patients and represent an unmet clinical need. Limited access of drugs into the brain because of the blood-brain barrier is at least partially responsible for therapeutic failure, necess