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pro vyhledávání: '"Ashley Sjolund"'
Autor:
Ashley Sjolund, Antonia A Nemec, Nicolas Paquet, Aishwarya Prakash, Patrick Sung, Sylvie Doublié, Joann B Sweasy
Publikováno v:
PLoS Genetics, Vol 10, Iss 11, p e1004753 (2014)
Thymine DNA glycosylase (TDG) functions in base excision repair, a DNA repair pathway that acts in a lesion-specific manner to correct individual damaged or altered bases. TDG preferentially catalyzes the removal of thymine and uracil paired with gua
Externí odkaz:
https://doaj.org/article/93139c9ef2e74d0eb55e6d9ef8a8044f
Publikováno v:
Environmental and Molecular Mutagenesis. 51:897-908
Personalized cancer therapy is likely to be one of the next big advances in our search for a cure for cancer. To be able to treat people in an individualized manner, researchers need to know a great deal about their genetic constitution and the DNA r
Autor:
Jason I. Herschkowitz, Susan G. Hilsenbeck, Xiaoxian Li, J. Michael Dixon, Helen Wong, Jeffrey M. Rosen, Ashley Sjolund, Xiaping He, Angel Rodriguez, Veronique Neumeister, M. Carolina Gutierrez, Cheng Fan, Dana Faratian, Anne Pavlick, Chad J. Creighton, David L. Rimm, Alexey Larionov, Lorna Renshaw, Jenny C. Chang, Xiaomei Zhang, Michael T. Lewis, Charles M. Perou, Melissa D. Landis
Publikováno v:
Proceedings of the National Academy of Sciences. 106:13820-13825
Some breast cancers have been shown to contain a small fraction of cells characterized by CD44 + /CD24 −/low cell-surface antigen profile that have high tumor-initiating potential. In addition, breast cancer cells propagated in vitro as mammosphere
Autor:
Sylvie Doublié, Ashley Sjolund, Antonia A. Nemec, Nicolas Paquet, Patrick Sung, Aishwarya Prakash, Joann B. Sweasy
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 10, Iss 11, p e1004753 (2014)
PLoS Genetics, Vol 10, Iss 11, p e1004753 (2014)
Thymine DNA glycosylase (TDG) functions in base excision repair, a DNA repair pathway that acts in a lesion-specific manner to correct individual damaged or altered bases. TDG preferentially catalyzes the removal of thymine and uracil paired with gua
Publikováno v:
Mutation research.
The base excision repair system is vital to the repair of endogenous and exogenous DNA damage. This pathway is initiated by one of several DNA glycosylases that recognizes and excises specific DNA lesions in a coordinated fashion. Methyl-CpG Domain P