Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Ashley R. Dunn"'
Publikováno v:
Nature structuralmolecular biology. 26(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21254c3efa9f565cb73f7aae6aa2a6ca
https://pubmed.ncbi.nlm.nih.gov/31548725
https://pubmed.ncbi.nlm.nih.gov/31548725
Autor:
Nicholas M, Gough, Jill, Gough, Donald, Metcalf, Anne, Kelso, Dianne, Grail, Nicos A, Nicola, Antony W, Burgess, Ashley R, Dunn
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f2169fcde2601c8188131535f4ec933
https://pubmed.ncbi.nlm.nih.gov/28320911
https://pubmed.ncbi.nlm.nih.gov/28320911
Autor:
C. Glenn Begley, Ashley R. Dunn, Hui Hua Zhang, Francesca Walker, Sunanda Basu, Antony W. Burgess, Christiaan J. M. Saris, Fenqiang Wu
Publikováno v:
Journal of Leukocyte Biology. 82:915-925
G-CSF and GM-CSF play important roles in regulating neutrophil production, survival, differentiation, and function. However, we have shown previously that G-CSF/GM-CSF double-deficient [knockout (KO)] mice still develop a profound neutrophilia in bon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a96e98922838d47cf7c08adfd485332b
https://doi.org/10.1189/jlb.0107023
https://doi.org/10.1189/jlb.0107023
Autor:
Ian R. Doyle, Richard I. Fisher, Otto D. Schoch, Ashley R. Dunn, K Uchida, Emi Hamano, Jeffrey J. Presneill, John F. Seymour, Koh Nakata
Publikováno v:
Thorax. 58:252-257
Background: Conventional measures of the severity of alveolar proteinosis (AP) include alveolar-arterial oxygen gradient ([A – a]Do 2 ), vital capacity (VC), and carbon monoxide transfer factor (Tlco), but alternative serological measures have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce95e496509257b5d593d67bcd1a6158
https://doi.org/10.1136/thorax.58.3.252
https://doi.org/10.1136/thorax.58.3.252
Autor:
Cathy Quilici, Franca Casagranda, Kenneth W. Harder, Jane E. Armes, Margaret L. Hibbs, Nicole Kountouri, David M. Tarlinton, Ashley R. Dunn
Publikováno v:
The Journal of Experimental Medicine
Genetic ablation of the Lyn tyrosine kinase has revealed unique inhibitory roles in B lymphocyte signaling. We now report the consequences of sustained activation of Lyn in vivo using a targeted gain-of-function mutation (Lynup/up mice). Lynup/up mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214ef7b35433405666be4dd0995642f1
https://doi.org/10.1084/jem.20020515
https://doi.org/10.1084/jem.20020515
Publikováno v:
Blood. 100:854-861
In steady-state hematopoiesis, G-CSF (granulocyte-colony stimulating factor) regulates the level of neutrophils in the bone marrow and blood. In this study, we have exploited the availability of G-CSF–deficient mice to evaluate the role of G-CSF in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fad7d966a8219f1df49b3763d66252
https://doi.org/10.1182/blood.v100.3.854
https://doi.org/10.1182/blood.v100.3.854
Autor:
Stacey T.T. I, Dianne Grail, Peter Lock, Toshio Kitamura, Andrew W. Roberts, Anne M. Verhagen, Cathy Quilici, Ashley R. Dunn, Raffi Gugasyan
Publikováno v:
The Journal of Cell Biology
Downstream of kinase (Dok)–related protein (DokR, also known as p56dok/FRIP/Dok-R) is implicated in cytokine and immunoreceptor signaling in myeloid and T cells. Tyrosine phosphorylation induces DokR to bind the signal relay molecules, RasGTPase-ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00e13ee09c687b9ea318b5ac43f5b48
https://doi.org/10.1083/jcb.200112066
https://doi.org/10.1083/jcb.200112066
Autor:
Stephen R. Holdsworth, Ashley R Dunn, Amanda L. Turner, Peter G. Tipping, A. Richard Kitching, Xiao Ru Huang
Publikováno v:
Monash University
Proliferative glomerulonephritis in humans is characterized by the presence of leukocytes in glomeruli. Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) can potentially stimulate or affect T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3215aa1760f7852476c5c6ab4db026e8
https://doi.org/10.1681/asn.v132350
https://doi.org/10.1681/asn.v132350
Autor:
Ulrike Novak, Ian P. Wicks, Ian K. Campbell, David M. Tarlinton, Fiona J. Clay, Paul Waring, Melissa Inglese, Shisan Bao, Joan K. Heath, Matthias Ernst, Warren S. Alexander, Ashley R. Dunn
Publikováno v:
The Journal of Experimental Medicine
The receptor subunit gp130 transduces multiple cell type-specific activities of the leukemia inhibitory factor (LIF)/interleukin (IL)-6 family of cytokines through the signal transducer and activator of transcription (STAT) and src homology 2 domain-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21683f0e8a2b9d8bf45299bb94f3ebd7
https://doi.org/10.1084/jem.194.2.189
https://doi.org/10.1084/jem.194.2.189
Autor:
Ian R. Doyle, Koh Nakata, Gordon H. Downie, Jeffrey J. Presneill, Takayuki Kitamura, David Langton, John F. Seymour, Ashley R. Dunn, Paul E. Moore, Otto D. Schoch, Janette M. Vincent, Michael C. Pain
Publikováno v:
American Journal of Respiratory and Critical Care Medicine, 163(2), 524-531. AMER THORACIC SOC
Alveolar proteinosis (AP) is characterized by excessive surfactant accumulation, and most cases are of unknown etiology. Standard therapy for AP is whole-lung lavage, which may not correct the underlying defect. Because the hematopoietic cytokine gra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9619659a99219713ade52d3f6435c27
https://doi.org/10.1164/ajrccm.163.2.2003146
https://doi.org/10.1164/ajrccm.163.2.2003146