Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ashley Peraza-Penton"'
Autor:
Mauro Truini, Kris C. Wood, Federica Baldi, Ivana Bozic, Kevin H. Lin, Lin Zhang, Ashley Peraza-Penton, Jingshan Tong, Federica Di Nicolantonio, Alberto Bardelli, Martin A. Nowak, Alice Lallo, Andrea Bertotti, Livio Trusolino, Sandra Misale
Publikováno v:
Nature Communications
Molecular targeted drugs are clinically effective anti-cancer therapies. However, tumours treated with single agents usually develop resistance. Here we use colorectal cancer (CRC) as a model to study how the acquisition of resistance to EGFR-targete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74caae82ff62d2e6c6dfe294b93df20d
http://hdl.handle.net/2318/1532747
http://hdl.handle.net/2318/1532747
Autor:
Zachary A. Cooper, Kris C. Wood, Ashley Peraza-Penton, Jennifer A. Wargo, J. Jasper, Keith T. Flaherty, Holly M. Alley, Katherine R. Singleton, Colin A. Martz, Suzanne E. Wardell, Michael T. Tetzlaff, Kathleen A. Ottina, Timothy C. Wang, Peter S. Winter, Pei Ling Chen, Jeffrey C. Rathmell, Grace R. Anderson, David M. Sabatini, Donald P. McDonnell, Lawrence N. Kwong
Publikováno v:
Science signaling. 7(357)
Cancer cells can activate diverse signaling pathways to evade the cytotoxic action of drugs. We created and screened a library of barcoded pathway-activating mutant complementary DNAs to identify those that enhanced the survival of cancer cells in th