Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ashley N. Luck"'
Autor:
Matthew Chung, Preston J. Basting, Rayanna S. Patkus, Alexandra Grote, Ashley N. Luck, Elodie Ghedin, Barton E. Slatko, Michelle Michalski, Jeremy M. Foster, Casey M. Bergman, Julie C. Dunning Hotopp
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 3243-3260 (2020)
Wolbachia is a genus containing obligate, intracellular endosymbionts with arthropod and nematode hosts. Numerous studies have identified differentially expressed transcripts in Wolbachia endosymbionts that potentially inform the biological interplay
Externí odkaz:
https://doaj.org/article/3e5d92a74bcd4481a9a2646cc7012433
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173186 (2017)
Efficient transcriptomic sequencing of microbial mRNA derived from host-microbe associations is often compromised by the much lower relative abundance of microbial RNA in the mixed total RNA sample. One solution to this problem is to perform extensiv
Externí odkaz:
https://doaj.org/article/f3b04bbd7ec94edc9957782bb20374f0
Autor:
Rayanna S. Patkus, Ashley N. Luck, Matthew Chung, Preston J. Basting, Barton E. Slatko, Jeremy M. Foster, Alexandra Grote, Casey M. Bergman, Michelle L. Michalski, Elodie Ghedin, Julie C. Dunning Hotopp
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 3243-3260 (2020)
Wolbachia is a genus containing obligate, intracellular endosymbionts with arthropod and nematode hosts. Numerous studies have identified differentially expressed transcripts in Wolbachia endosymbionts that potentially inform the biological interplay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ec56a5597d4364438ce2bcc2d17732
http://g3journal.org/lookup/doi/10.1534/g3.120.401534
http://g3journal.org/lookup/doi/10.1534/g3.120.401534
Autor:
Xiaojing Yuan, Iqbal Hamza, Ashley N. Luck, Jeremy M. Foster, Denis Voronin, Barton E. Slatko
Publikováno v:
The FASEB Journal
Nematodes lack a heme biosynthetic pathway and must acquire heme from exogenous sources. Given the indispensable role of heme, this auxotrophy may be exploited to develop drugs that interfere with heme uptake in parasites. Although multiple heme-resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d329c641e3c9bfd2c7cc6d78a6dc2e5d
https://doi.org/10.1096/fj.201600603r
https://doi.org/10.1096/fj.201600603r
Autor:
Ashley N. Luck, Rays H. Y. Jiang, Amruta S. Mhashilkar, Weam I. Zaky, Barton E. Slatko, Andrew R. Moorhead, Thomas R. Unnasch, Steven A. Williams, Swamy R. Adapa
Publikováno v:
International Journal for Parasitology. 46:333-341
A homologue of the ecdysone receptor has been identified and shown to be responsive to 20-hydroxyecdysone in Brugia malayi. However, the role of this master regulator of insect development has not been delineated in filarial nematodes. Gravid adult f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e045645f2d9a4924c59ad82c3474a9d
https://doi.org/10.1016/j.ijpara.2016.01.005
https://doi.org/10.1016/j.ijpara.2016.01.005
Publikováno v:
Molecular and Biochemical Parasitology. 195:88-95
Most human filarial nematode parasites and arthropods are hosts for a bacterial endosymbiont, Wolbachia. In filaria, Wolbachia are required for normal development, fertility and survival, whereas in arthropods, they are largely parasitic and can infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff456e70ede30b26c8813d0d8e43123
https://doi.org/10.1016/j.molbiopara.2014.07.004
https://doi.org/10.1016/j.molbiopara.2014.07.004
Autor:
Jeremy M. Foster, Fana B. Mersha, Ashley N. Luck, Leslie K. Cortes, Colleen McClung, Cristian I. Ruse, Christopher H. Taron
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0216849 (2019)
PLoS ONE
PLoS ONE
Further characterization of essential systems in the parasitic filarial nematodeBrugia malayiis needed to better understand its biology, its interaction with its hosts, and to identify critical components that can be exploited to develop novel treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee2a216c0dddf37eae27a26cefe57fc
https://doi.org/10.1371/journal.pone.0216849
https://doi.org/10.1371/journal.pone.0216849
Publikováno v:
Biochemistry. 52:8333-8341
It has been previously suggested that large amounts of oxalate in plasma could play a role in autism by binding to the bilobal iron transport protein transferrin (hTF), thereby interfering with iron metabolism by inhibiting the delivery of iron to ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38dd2ad6d7ab617f3eda4775c3c57284
https://doi.org/10.1021/bi401190m
https://doi.org/10.1021/bi401190m
Autor:
Anne B. Mason, Ashley N. Luck
Publikováno v:
Advanced Drug Delivery Reviews. 65:1012-1019
Highly proliferative cells have a dramatically increased need for iron which results in the expression of an increased number of transferrin receptors (TFR). This insight makes the transferrin receptor on these cells an excellent candidate for target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345856bf9841be6e591e56d7cfdb0ecf
https://doi.org/10.1016/j.addr.2012.11.001
https://doi.org/10.1016/j.addr.2012.11.001
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 3, p e0173186 (2017)
PLoS ONE, Vol 12, Iss 3, p e0173186 (2017)
Efficient transcriptomic sequencing of microbial mRNA derived from host-microbe associations is often compromised by the much lower relative abundance of microbial RNA in the mixed total RNA sample. One solution to this problem is to perform extensiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a98ee50b3696a922c30ee4a70226909
https://doi.org/10.1371/journal.pone.0173186
https://doi.org/10.1371/journal.pone.0173186