Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ashley N. Connelly"'
Autor:
Ashley N. Connelly, Richard P. H. Huijbregts, Harish C. Pal, Valeriya Kuznetsova, Marcus D. Davis, Krystle L. Ong, Christian X. Fay, Morgan E. Greene, Edgar T. Overton, Zdenek Hel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Neutrophils are the most abundant circulating leukocyte population with critical roles in immune defense, regulation of innate and adaptive immune systems, and disease pathogenesis. Our progress in understanding precise mechanisms of neutrop
Externí odkaz:
https://doaj.org/article/6b8d06a67b1c44c3b330ffebdad63b65
Autor:
Krystle L. Ong, Marcus D. Davis, Kalyn K. Purnell, Hannah Cutshall, Harish C. Pal, Ashley N. Connelly, Christian X. Fay, Valeriya Kuznetsova, Elizabeth E. Brown, Zdenek Hel
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
Hematologic malignancies, including multiple myeloma (MM), promote systemic immune dysregulation resulting in an alteration and increased plasticity of myeloid cell subsets. To determine the heterogeneity of the myeloid cell compartment in the periph
Externí odkaz:
https://doaj.org/article/2be955a6dc4a4a0b9c6d7306f1f11214
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Previously we established that human C-reactive protein (CRP) exacerbates mouse acute kidney injury and that the effect was associated with heightened renal accumulation of myeloid derived cells with suppressor functions (MDSC). Herein we provide dir
Externí odkaz:
https://doaj.org/article/ed00b84877704a9da4dbbc60ecd08a4d
Autor:
Ashley N Connelly, Harish Pal, Marcus Davis, Krystle Ong, Valeriya Kuznetsova, Christian Fay, E. Turner Overton, Zdenek Hel
Publikováno v:
The Journal of Immunology. 204:225.32-225.32
Despite successful viral control, HIV-1-infected individuals have a higher risk of developing life-threatening comorbidities including liver and cardiovascular diseases which are associated with inflammation and immune dysregulation. However, the spe