Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ashley N Payan"'
Autor:
Oscar Ekpenyong, Candace Cooper, Jing Ma, Naihsuan C. Guy, Ashley N. Payan, Fuqiang Ban, Artem Cherkasov, Marc B. Cox, Dong Liang, Huan Xie
Publikováno v:
Pharmaceuticals, Vol 13, Iss 11, p 386 (2020)
Background: GMC1 (2-(1H-benzimidazol-2-ylsulfanyl)-N-[(Z)-(4-methoxyphenyl) methylideneamino] acetamide) effectively inhibits androgen receptor function by binding directly to FKBP52. This is a novel mechanism for the treatment of castration resistan
Externí odkaz:
https://doaj.org/article/2618ea822bf5400b9641607a3a58a63b
Autor:
Diondra C. Harris, Yenni A. Garcia, Cheryl Storer Samaniego, Veronica W. Rowlett, Nina R. Ortiz, Ashley N. Payan, Tatsuya Maehigashi, Marc B. Cox
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5346 (2019)
Previous studies demonstrated that the 52-kDa FK506-binding protein (FKBP52) proline-rich loop is functionally relevant in the regulation of steroid hormone receptor activity. While zebra fish (Danio rerio; Dr) FKBP52 contains all of the analogous do
Externí odkaz:
https://doaj.org/article/ecd2cb98a0ed43619269fc2cb98db8ee
Autor:
Artem Cherkasov, Ashley N Payan, Fuqiang Ban, Naihsuan Guy, Huan Xie, Candace Cooper, Dong Liang, Oscar Ekpenyong, Jing Ma, Marc B. Cox
Publikováno v:
Pharmaceuticals
Volume 13
Issue 11
Pharmaceuticals, Vol 13, Iss 386, p 386 (2020)
Volume 13
Issue 11
Pharmaceuticals, Vol 13, Iss 386, p 386 (2020)
Background: GMC1 (2-(1H-benzimidazol-2-ylsulfanyl)-N-[(Z)-(4-methoxyphenyl) methylideneamino] acetamide) effectively inhibits androgen receptor function by binding directly to FKBP52. This is a novel mechanism for the treatment of castration resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b65bedf7fd4fb591e69fb86b8014e4
http://europepmc.org/articles/PMC7698315
http://europepmc.org/articles/PMC7698315
Autor:
Nina R. Ortiz, Laura J. Blair, Marc B. Cox, Jeffrey C. Sivils, David S. Culbertson, Jane Dyson, Ashley N Payan, Dan Finley, Jazzmin Jovonna Owens, Jason E. Gestwicki, Szu Yu Kuo, William E. Balch, Jaideep Chaudhary, Jay Singh, Darren M. Hutt, Chad A. Dickey, Naihsuan Guy, Bradley D. Tait, Shravan Kumar Komaragiri
Publikováno v:
Cell chemical biology, vol 27, iss 3
Cell Chem Biol
Cell Chem Biol
Summary Hsp90 plays an important role in health and is a therapeutic target for managing misfolding disease. Compounds that disrupt co-chaperone delivery of clients to Hsp90 target a subset of Hsp90 activities, thereby minimizing the toxicity of pan-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c800b824e420391f461894a73274c69
https://escholarship.org/uc/item/3k55j4vx
https://escholarship.org/uc/item/3k55j4vx
Autor:
Yenni A. Garcia, Veronica W Rowlett, Ashley N Payan, Diondra C. Harris, Cheryl Storer Samaniego, Marc B. Cox, Tatsuya Maehigashi, Nina R. Ortiz
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5346 (2019)
Volume 20
Issue 21
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5346 (2019)
Volume 20
Issue 21
Previous studies demonstrated that the 52-kDa FK506-binding protein (FKBP52) proline-rich loop is functionally relevant in the regulation of steroid hormone receptor activity. While zebra fish (Danio rerio
Dr) FKBP52 contains all of the analogou
Dr) FKBP52 contains all of the analogou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006fe425079153a2fa994f2a005ec84c
https://doi.org/10.3390/ijms20215346
https://doi.org/10.3390/ijms20215346