Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ashley Menk"'
Autor:
Jian Ding, Sarah Guyette, Brett Schrand, Jessica Geirut, Holly Horton, Guangwu Guo, Greg Delgoffe, Ashley Menk, Patrick A. Baeuerle, Robert Hofmeister, Robert Tighe
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTT cell Receptor (TCR) Fusion Construct (TRuC®) T cells harness all signaling subunits of the TCR to activate T cells and eliminate tumor cells, with minimal release of cytokines. While adoptive cell therapy with chimeric antigen receptor (CA
Externí odkaz:
https://doaj.org/article/a9b5bc18fcbc470686b5254f3755bf59
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/7df4c475ffa641f68c9fd1f9930d15d5
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/90dd5e8a2a5042f7a7befdf016f19033
Autor:
Ryan Whetstone, Greg Delgoffe, Paolo Vignali, Kristin DePeaux, McLane Watson, Ashley Menk, Steven Mullet, Ronal Peralta, Stephanie Grebinoski, Natalie Rittenhouse, Amanda Poholek, Brett Morrison, Jeffrey Rothstein, Stacy Wendell
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/80250980be9f420b827b9a6cf622e899
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/d3bb04d2103a49368c205e20334146b3
Autor:
Shankar Revu, Jing Wu, Matthew Henkel, Natalie Rittenhouse, Ashley Menk, Greg M. Delgoffe, Amanda C. Poholek, Mandy J. McGeachy
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2642-2653 (2018)
Summary: Th17 cells drive autoimmune disease but also control commensal microbes. A common link among antigens from self-proteins or commensal microbiota is relatively low activation of T cell receptor (TCR) and costimulation signaling. Indeed, stron
Externí odkaz:
https://doaj.org/article/ccc4f882024b4e13883ca1100600cc92
Autor:
Ansen Burr, Junyi Ji, Kadir Ozler, Heather Mentrup, Onur Eskiocak, Rachel Cumberland, Ashley Menk, Xiaoyi Zhang, Abigail Overacre-Delgoffe, Natalie Rittenhouse, Chris Marshall, Vaughn Cooper, Amanda Poholek, Greg Delgoffe, Semir Beyaz, Timothy Hand
Publikováno v:
Gastroenterology. 164:S60
The colonic epithelium requires continuous renewal by crypt resident intestinal stem cells (ISCs) and transit amplifying (TA) cells to maintain barrier integrity, especially after inflammatory damage. An important regulator of ISC and TA cell functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef66fbcf89eb1207fedad9d555bb9af
https://doi.org/10.1053/j.gastro.2023.03.113
https://doi.org/10.1053/j.gastro.2023.03.113
Autor:
Greg Delgoffe, Paolo Vignali, Kristin DePeaux, McLane Watson, Konstantinos Lontos, Nicole McGaa, Nicole Scharping, Ashley Menk
While CD8+ cytotoxic T cells are clearly critical for identification and elimination of cancer cells, factors concentrated within the tumor microenvironment drive their altered differentiation to a hypofunctional, short-lived state termed exhaustion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6ecd1af4fcc70af2838367e1a4bd216
https://doi.org/10.21203/rs.3.rs-924657/v1
https://doi.org/10.21203/rs.3.rs-924657/v1
IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival
Autor:
Saikat, Majumder, Nilesh, Amatya, Shankar, Revu, Chetan V, Jawale, Dongwen, Wu, Natalie, Rittenhouse, Ashley, Menk, Saran, Kupul, Fang, Du, Itay, Raphael, Amrita, Bhattacharjee, Ulrich, Siebenlist, Timothy W, Hand, Greg M, Delgoffe, Amanda C, Poholek, Sarah L, Gaffen, Partha S, Biswas, Mandy J, McGeachy
Publikováno v:
Nature immunology. 20(5)
Lymph-node (LN) stromal cell populations expand during the inflammation that accompanies T cell activation. Interleukin-17 (IL-17)-producing helper T cells (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf5b36dec8d4668a55ed9d9bf96d96bc
https://pubmed.ncbi.nlm.nih.gov/30971770
https://pubmed.ncbi.nlm.nih.gov/30971770
Autor:
Mandy J. McGeachy, Shankar Revu, Jing Wu, Natalie Rittenhouse, Ashley Menk, Greg M. Delgoffe, Amanda C. Poholek
Publikováno v:
The Journal of Immunology. 200:164.1-164.1
Th17 cells drive autoimmune disease but also control commensal microbes. A common link between antigens from self-proteins or commensal microbiota is relatively low activation of T cell receptor and costimulation signaling. Indeed, strong TCR/CD28 st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84f8db5c80979be7ed6af2d6feabe054
https://doi.org/10.4049/jimmunol.200.supp.164.1
https://doi.org/10.4049/jimmunol.200.supp.164.1