Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ashley McDonough"'
Autor:
Ashley McDonough, Gina E. Elsen, Ray M. Daza, Amelia R. Bachleda, Donald Pizzo, Olivia M. DelleTorri, Robert F. Hevner
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2021)
Previous studies demonstrated specific expression of transcription factor Tbr2 in unipolar brush cells (UBCs) of the cerebellum during development and adulthood. To further study UBCs and the role of Tbr2 in their development we examined UBC morpholo
Externí odkaz:
https://doaj.org/article/2c6db8e45adf44d396ba09b2448b19f2
Publikováno v:
Stem Cells International, Vol 2012 (2012)
Spinal cord injury (SCI) results in motor and sensory deficits, the severity of which depends on the level and extent of the injury. Animal models for SCI research include transection, contusion, and compression mouse models. In this paper we will di
Externí odkaz:
https://doaj.org/article/3d676b567fa94b088f09c1c2a27835c8
Autor:
Jonathan R Weinstein, Ruth D Lee, Yi-je Jay Chen, Mitzi Adler-Wachter, Brendan Schweitzer, Ashley McDonough, Heike Wulff
Publikováno v:
Stroke. 54
Background: Acute ischemic stroke (AIS) is a leading cause of death and long-term disability. Both microglia (MG) and infiltrating macrophages (MP) are critical effector cell types in ischemic brain injury and recovery. K Ca 3.1 is a calcium-activate
Autor:
Margaret Hamner, Ashley McDonough, Cara Nielson, Davin Gong, Levi Todd, German Rojas, Thomas Reh, Bruce R Ransom, Jonathan R Weinstein
Publikováno v:
Stroke. 54
Background: Ischemic preconditioning (IPC) is a robust protective phenomenon whereby brief ischemic exposure confers protection against a subsequent prolonged ischemic challenge. IPC has been studied primarily in gray matter predominant models, howev
Autor:
Katherine E. Prater, Rachel A. Chernoff, Macarena S. Aloi, Jasmine L. Pathan, Jonathan Weinstein, Gwenn A. Garden, Chloe N. Winston, Matthew P. Sadgrove, Stephanie Davidson, Wei Su, Ashley McDonough, Dannielle Zierath
Publikováno v:
J Neurosci
Microglia maintain brain health and play important roles in disease and injury. Despite the known ability of microglia to proliferate, the precise nature of the population or populations capable of generating new microglia in the adult brain remains
Autor:
Margaret A. Hamner, Ashley McDonough, Davin C. Gong, Levi J. Todd, German Rojas, Sibylle Hodecker, Christopher B. Ransom, Thomas A. Reh, Bruce R. Ransom, Jonathan R. Weinstein
Publikováno v:
Glia
Ischemic preconditioning (IPC) is a phenomenon whereby a brief, non-injurious ischemic exposure enhances tolerance to a subsequent ischemic challenge. The mechanism of IPC has mainly been studied in rodent stroke models where gray matter (GM) constit
Autor:
Thomas Möller, James S. Strosnider, Jasmine Shen, Jonathan R. Weinstein, Shahani Noor, Richard V. Lee, Ashley McDonough, Ryan Dodge, Gwenn A. Garden, Stephanie Davidson
Publikováno v:
Glia
Ischemic preconditioning (IPC) is an experimental phenomenon in which a sub-threshold ischemic insult applied to the brain reduces damage caused by a subsequent more severe ischemic episode. Identifying key molecular and cellular mediators of IPC wil
Autor:
Ray A M Daza, Ashley McDonough, Olivia M DelleTorri, Amelia R Bachleda, Robert F. Hevner, Gina E. Elsen, Donald P. Pizzo
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2021)
Frontiers in Neuroscience
Frontiers in Neuroscience
Previous studies demonstrated specific expression of transcription factor Tbr2 in unipolar brush cells (UBCs) of the cerebellum during development and adulthood. To further study UBCs and the role of Tbr2 in their development we examined UBC morpholo
Publikováno v:
Neurotherapeutics. 15:511-524
Ischemic preconditioning (IPC) is a robust neuroprotective phenomenon in which a brief period of cerebral ischemia confers transient tolerance to subsequent ischemic challenge. Research on IPC has implicated cellular, molecular, and systemic elements
Publikováno v:
Neurochemical Research. 42:2625-2638
Microglia, the resident immune cells of the CNS, are primary regulators of the neuroimmune response to injury. Type I interferons (IFNs), including the IFNαs and IFNβ, are key cytokines in the innate immune system. Their activity is implicated in t