Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ashley M. Fenn"'
Autor:
Binod Aryal, Noemi Rotllan, Elisa Araldi, Cristina M. Ramírez, Shun He, Benjamin G. Chousterman, Ashley M. Fenn, Amarylis Wanschel, Julio Madrigal-Matute, Nikhil Warrier, Jose L. Martín-Ventura, Filip K. Swirski, Yajaira Suárez, Carlos Fernández-Hernando
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Angiopoietin-like 4 protein (ANGPTL4) is a regulator of lipoprotein metabolism whose role in atherosclerosis has been controversial. Here the authors show that ANGPTL4 deficiency in haematopoietic cells increases atherogenesis by promoting myeloid pr
Externí odkaz:
https://doaj.org/article/40a361abcb9741eda09eb9b03b905155
Autor:
Peter Libby, Vanessa Frodermann, Friedrich Felix Hoyer, Christoph J. Binder, Christopher T. Chan, Annemijn F. Gregory, Yoshiko Iwamoto, Anne Vassalli, Cameron S. McAlpine, Matthias Nahrendorf, Atsushi Anzai, Filip K. Swirski, Thomas E. Scammell, Shun He, Florian Kahles, Wolfram C. Poller, Ashley M. Fenn, Mehdi Tafti, John E. Mindur, Colin Valet, Sara Rattik, Lennard Halle, M. Kiss
Publikováno v:
Nature
Nature, vol. 566, no. 7744, pp. 383-387
Nature, vol. 566, no. 7744, pp. 383-387
Sleep is integral to life 1 . Although insufficient or disrupted sleep increases the risk of multiple pathological conditions, including cardiovascular disease 2 , we know little about the cellular and molecular mechanisms by which sleep maintains ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce735b02272ecc0fdf0ecec71fd5eaa
http://europepmc.org/articles/PMC6442744
http://europepmc.org/articles/PMC6442744
Autor:
Kenneth Walsh, Matthias Nahrendorf, Shun He, Filip K. Swirski, John E. Mindur, Manfred Nairz, Lennard Halle, Sara Rattik, Soichi Sano, Jennifer L. Choi, Christopher T. Chan, De Lisa Fairweather, Florian Kahles, Ashley M. Fenn, Atsushi Anzai, Colin Valet, Yoshiko Iwamoto, Peter Libby, Cameron S. McAlpine
Publikováno v:
The Journal of Experimental Medicine
In autoimmune myocarditis, self-reactive T cells attack cardiac antigens and contribute to heart inflammation. In this study, Anzai et al. show that the T cell–derived cytokine and growth factor IL-3 amplifies inflammation and exacerbates autoimmun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b0949e341628e6ff01d92cca51a9f3
https://doi.org/10.1084/jem.20180722
https://doi.org/10.1084/jem.20180722
Autor:
Nina K. Harder, Jyoti Patel, Florian Kahles, Yoshiko Iwamoto, John E. Mindur, Cameron S. McAlpine, Jan-Åke Gustafsson, Ruslan I. Sadreyev, Laurent Yvan-Charvet, Filip K. Swirski, Shun He, Henrike Janssen, David R. Koolbergen, Wolfram C. Poller, Lai Ping Wong, Ashley M. Fenn, Christopher T. Chan, Sara Rattik, Alan R. Tall, Carlos Fernández-Hernando, Anja M. van der Laan, Marit Westerterp, Colin Valet, Atsushi Anzai, Matthias Nahrendorf
Publikováno v:
Journal of Experimental Medicine, 217(10):20200318. ROCKEFELLER UNIV PRESS
Journal of experimental medicine, 217(10):20200318. Rockefeller University Press
The Journal of Experimental Medicine
Journal of experimental medicine, 217(10):20200318. Rockefeller University Press
The Journal of Experimental Medicine
Liver X receptors (LXRs) orchestrate cholesterol metabolism with diverse metabolic and immune functions. Chan et al. show that in the thymus, thymic epithelial cells protect against involution and promote regeneration, whereas T cells require LXRs to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae13dd071a1c8d2abdcb9d063115dac4
https://doi.org/10.1084/jem.20200318
https://doi.org/10.1084/jem.20200318
Publikováno v:
Hormones and Behavior. 89:92-97
Free-living ground squirrel species are sexually dimorphic in hibernation phenology. The underlying causes of these differences are not yet known. Androgens, testosterone (T) in particular, inhibit hibernation. To determine the influence of endogenou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e581b06a30fc3c28452b849193f266
https://doi.org/10.1016/j.yhbeh.2016.12.007
https://doi.org/10.1016/j.yhbeh.2016.12.007
Autor:
Benoit Tricot, Atsushi Anzai, Manfred Nairz, Filip K. Swirski, Ashley M. Fenn, Sara Rattik, Ralph Weissleder, Yoshiko Iwamoto, John E. Mindur, Jennifer L. Choi, Cameron S. McAlpine, Burkhard Becher, Matthias Nahrendorf, Peter Libby, Gregory R. Wojtkiewicz, James R. Stone, Shun He, Christopher T. Chan
Publikováno v:
The Journal of Experimental Medicine
Myocardial infarction elicits massive recruitment of monocytes and neutrophils to the myocardium, but the mechanisms that control these processes are not fully understood. Here, Anzai et al. show that GM-CSF is a powerful orchestrator contributing to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38277c0305b05cd0bee68ad9e1c069dd
http://europepmc.org/articles/PMC5679174
http://europepmc.org/articles/PMC5679174
Autor:
Yoshiko Iwamoto, Ralph Weissleder, Yu-Xiang Ye, Peter Libby, Martin Brandt, Benoit Tricot, Filip K. Swirski, Ingo Hilgendorf, Matthias Nahrendorf, Colin H. Macphee, Ashley M. Fenn, Shun He, Benjamin G. Chousterman, Atsushi Anzai, Yuan Sun, Manfred Nairz
Publikováno v:
Circulation. Heart Failure
Supplemental Digital Content is available in the text.
Background— Healing after myocardial infarction (MI) involves the biphasic accumulation of inflammatory Ly-6Chigh and reparative Ly-6Clow monocytes/macrophages. Excessive inflammation disr
Background— Healing after myocardial infarction (MI) involves the biphasic accumulation of inflammatory Ly-6Chigh and reparative Ly-6Clow monocytes/macrophages. Excessive inflammation disr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd61785fd4cdbbaa77a191bb3b426ae2
https://doi.org/10.1161/circheartfailure.115.002334
https://doi.org/10.1161/circheartfailure.115.002334
Autor:
Benjamin G. Chousterman, Georg F. Weber, Ashley M. Fenn, Triantafyllos Chavakis, Shun He, Markus A. Weigand, Yoshiko Iwamoto, Atsushi Anzai, Clinton S. Robbins, Nuh N. Rahbari, Manfred Nairz, Stefan Hofer, Sebastian Schölch, Anne Klotzsche-von Ameln, Filip K. Swirski, L Noiret, Tina Zönnchen, Sarah L. Maier, Matthias Nahrendorf, Jürgen Weitz, Florian Uhle, Thorsten Brenner, Ralph Weissleder
Publikováno v:
Science. 347:1260-1265
A new therapeutic target for sepsis Infections can sometimes unleash powerful immune responses that careen out of control, leading to sepsis, organ failure, and death. Although antibiotics can help to quash the infection, sepsis patients also need th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a9ae2e48864967a3e8848252b3ddc68
https://doi.org/10.1126/science.aaa4268
https://doi.org/10.1126/science.aaa4268
Autor:
Filip K. Swirski, Ashley M. Fenn
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 37(2)
Atherosclerosis is a chronic lipid-driven inflammatory disease that involves the recruitment, infiltration, differentiation, and proliferation of monocytes and monocyte-derived macrophages. In the absence of these cells, disease neither initiates nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d62618a295cdeb313184753682c04f
https://pubmed.ncbi.nlm.nih.gov/27856455
https://pubmed.ncbi.nlm.nih.gov/27856455
Autor:
Ashley M. Fenn
Publikováno v:
Postdoc Journal. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cca65c36c1a86c24978f05a21e951732
https://doi.org/10.14304/surya.jpr.v5n1.1
https://doi.org/10.14304/surya.jpr.v5n1.1