Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ashley M Kopec"'
Autor:
Anca R Rǎdulescu, Gabrielle C Todd, Cassandra L Williams, Benjamin A Bennink, Alex A Lemus, Haley E Chesbro, Justin R Bourgeois, Ashley M Kopec, Damian G Zuloaga, Annalisa Scimemi
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 2, p e1009845 (2022)
Glutamate transporters preserve the spatial specificity of synaptic transmission by limiting glutamate diffusion away from the synaptic cleft, and prevent excitotoxicity by keeping the extracellular concentration of glutamate at low nanomolar levels.
Externí odkaz:
https://doaj.org/article/f22b42385d4a442d8946629efe36da44
Autor:
Charly Abi-Ghanem, Abigail E. Salinero, David Kordit, Febronia M. Mansour, Richard D. Kelly, Harini Venkataganesh, Nyi-Rein Kyaw, Olivia J. Gannon, David Riccio, Gabrielle Fredman, Yannick Poitelon, Sophie Belin, Ashley M. Kopec, Lisa S. Robison, Kristen L. Zuloaga
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Background Damage to the cerebral vasculature can lead to vascular contributions to cognitive impairment and dementia (VCID). A reduction in blood flow to the brain leads to neuropathology, including neuroinflammation and white matter lesion
Externí odkaz:
https://doaj.org/article/aacccfdac891497eb2cfeef1549ade4f
Publikováno v:
bioRxiv
Evolutionarily conserved, peer-directed social behaviors are essential to participate in many aspects of human society. These behaviors directly impact psychological, physiological, and behavioral maturation. Adolescence is an evolutionarily conserve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8188e9731ab45cfefac0bbf25a523c
https://europepmc.org/articles/PMC10187149/
https://europepmc.org/articles/PMC10187149/
Publikováno v:
bioRxiv
Adolescence is a period of copious neural development, particularly in the ‘reward’ circuitry of the brain, and reward-related behavioral development, including social development. One neurodevelopmental mechanism that appears to be common across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75fe34824e355f653b8030699b36f592
https://europepmc.org/articles/PMC10187173/
https://europepmc.org/articles/PMC10187173/
Autor:
Christopher Figueroa, Erin L. Edgar, J. M. Kirkland, Ishan Patel, David N. King’uyu, Ashley M. Kopec
Social networks and support are integral to health and wellness across the lifespan, and social engagement may be particularly important during aging. However, social behavior and social cognition decline naturally during aging across species. Social
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6eb714ff260de8d7b18e4cc90294df9
https://doi.org/10.1101/2023.04.27.538622
https://doi.org/10.1101/2023.04.27.538622
Publikováno v:
bioRxiv
Drug exposure during adolescence, when the ‘reward’ circuitry of the brain is developing, can permanently impact reward-related behavior. Epidemiological studies show that opioid treatment during adolescence, such as pain management for a dental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab603a6e3afef83b3bcf7613981245c
https://europepmc.org/articles/PMC10153224/
https://europepmc.org/articles/PMC10153224/
Publikováno v:
Cells, Vol 9, Iss 4, p 812 (2020)
Myelin is critical for the proper function of the nervous system and one of the most complex cell–cell interactions of the body. Myelination allows for the rapid conduction of action potentials along axonal fibers and provides physical and trophic
Externí odkaz:
https://doaj.org/article/55e8775e54c040108764f17ccf696dd1
Autor:
David N. King’uyu, Lily Nti-Kyemereh, Jesse L. Bonin, Paul J. Feustel, Michelle Tram, Katherine C. MacNamara, Ashley M. Kopec
Opioids have long been used for clinical pain management, but also have addictive properties that have contributed to the ongoing opioid epidemic. While opioid activation of opioid receptors is well known to contribute to reward and reinforcement, da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da50ed28b692d936bb0ecb050e413cce
https://doi.org/10.1101/2022.10.03.510683
https://doi.org/10.1101/2022.10.03.510683
Publikováno v:
J Neurosci
Long-term memory (LTM) formation is a critical survival process by which an animal retains information about prior experiences to guide future behavior. In the experimentally advantageous marine molluskAplysia, LTM for sensitization can be induced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f0febb233ba57a38bfca436659709a
https://doi.org/10.1523/jneurosci.2284-20.2020
https://doi.org/10.1523/jneurosci.2284-20.2020
Autor:
Sophie Belin, Yannick Poitelon, Abigail Hellman, Leandro N. Marziali, Jacob Herron, Ashley M. Kopec, Urja Bhatia, Haley Jeanette, Maria Laura Feltri
Publikováno v:
Glia
YAP and TAZ are effectors of the Hippo pathway that controls multicellular development by integrating chemical and mechanical signals. Peripheral nervous system development depends on the Hippo pathway. We previously showed that loss of YAP and TAZ i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d351570bfa894fc07e397fa6676ece21
http://europepmc.org/articles/PMC7898398
http://europepmc.org/articles/PMC7898398