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pro vyhledávání: '"Ashley L. Doruelo"'
Autor:
Ashley L. Doruelo, Pamela A. Christopherson, Sandra L. Haberichter, Steven R. Lentz, Veronica H. Flood, Robert R. Montgomery, Amy D. Shapiro, Lisa N. Boggio, Sweta Gupta
Essentials The pathophysiology of type 2M von Willebrand disease (VWD) is poorly understood. Sequence variations in type 2M VWD subjects were characterized. A high degree of clinical and laboratory variability exists within type 2M VWD variants. Some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf6bab9b7781ce6076ba65cd2446239
https://europepmc.org/articles/PMC5538962/
https://europepmc.org/articles/PMC5538962/
Autor:
Tricia L Slobodianuk, Derek Adams, Veronica H. Flood, Hartmut Weiler, Shawn Kalloway, Jamie Foeckler, Ashley L. Doruelo, Robert R. Montgomery
Publikováno v:
Blood. 126:211-211
VWF binding to type 4 collagen has recently been shown to occur via the VWF A1 domain, but the clinical implications of this interaction remain to be elucidated. In humans, the R1399H sequence variant (2% of the Caucasian population is heterozygous f