Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ashley L, Eadie"'
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Drug repurposing has gained significant interest in recent years due to the high costs associated with de novo drug development; however, comprehensive pharmacological information is needed for the translation of pre‐existing drugs across
Externí odkaz:
https://doaj.org/article/0df18e265eb7434b91edf3e13c5724f2
Autor:
Victoria L. Nelson, Ashley L. Eadie, Lester Perez, Malav Madhu, Mathew Platt, Angella Mercer, Thomas Pulinilkunnil, Petra Kienesberger, Jeremy A. Simpson, Keith R. Brunt
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1299 (2024)
Myocardial infarction and reperfusion constitute a complex injury consisting of many distinct molecular stress patterns that influence cardiomyocyte survival and adaptation. Cell signalling, which is essential to cardiac development, also presents po
Externí odkaz:
https://doaj.org/article/b0d501f4bb1c4babaebb502100a53e50
Publikováno v:
Physiological Reports, Vol 10, Iss 4, Pp n/a-n/a (2022)
Abstract Limited data exist regarding the impact of an acute bout of exercise with varying intensities on irisin levels in the youth of different obesity statuses. The objectives were to (1) compare an acute bout of moderate continuous intensity (MCI
Externí odkaz:
https://doaj.org/article/576ef203cd9d42aa88919b29acfc8b88
Autor:
Benjamin H. Colpitts, Ken Seaman, Ashley L. Eadie, Keith R. Brunt, Danielle R. Bouchard, Martin Sénéchal
Publikováno v:
Physiological Reports, Vol 9, Iss 11, Pp n/a-n/a (2021)
Abstract Metabolic flexibility is the ability to adapt substrate oxidation according to metabolic demand. Exercise increases fat oxidation responses in individuals living with obesity; however, limited research exists on the relationship between subs
Externí odkaz:
https://doaj.org/article/1c0c0d0ceffd42b18344cd0803e1ea46
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 3, Pp n/a-n/a (2021)
Abstract Federal regulatory agencies such as the United States Food and Drug Administration review pharmacological evidence to ensure the safety and efficacy of new and repurposed pharmaceuticals prior to market approval. The discussions, disagreemen
Externí odkaz:
https://doaj.org/article/0b08f6bce9ae494ba61d41ff51486c1d
Autor:
Taiana M. Pierdoná, Alexandria Martin, Patience O. Obi, Samira Seif, Benjamin Bydak, Hagar I. Labouta, Ashley L. Eadie, Keith R. Brunt, Jonathan M. McGavock, Martin Sénéchal, Ayesha Saleem
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 5, p 143 (2022)
Background: Exercise is associated with health benefits, including the prevention and management of obesity. However, heterogeneity in the adaptive response to exercise training exists. Our objective was to evaluate if changes in extracellular vesicl
Externí odkaz:
https://doaj.org/article/e22d346aa173407faf7d4352daf1d381
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 322:H1028-H1031
Autor:
Jill Fox, Danielle R. Bouchard, Ashley L. Eadie, Brittany V. Rioux, Keith R. Brunt, Martin Sénéchal
Publikováno v:
Applied Physiology, Nutrition, and Metabolism. 46:1248-1256
Studies show aerobic exercise increases irisin and leads to health benefits. The impact of circuit training (CT) on irisin in overweight younger and older adults is unknown. The objectives were to determine whether, during an acute bout of CT, change
Autor:
Ayesha Saleem, Martin Sénéchal, Jonathan M. McGavock, Keith R. Brunt, Ashley L. Eadie, Hagar I. Labouta, Benjamin Bydak, Samira Seif, Patience O. Obi, Alexandria Martin, Taiana M. Pierdoná
Publikováno v:
Frontiers in bioscience (Landmark edition). 27(5)
Exercise is associated with health benefits, including the prevention and management of obesity. However, heterogeneity in the adaptive response to exercise training exists. Our objective was to evaluate if changes in extracellular vesicles (EVs) aft
Autor:
Keith R. Brunt, Benjamin H. Colpitts, Danielle R. Bouchard, Martin Sénéchal, Ashley L. Eadie, Ken Seaman
Publikováno v:
Physiological Reports, Vol 9, Iss 11, Pp n/a-n/a (2021)
Physiological Reports
Physiological Reports
Metabolic flexibility is the ability to adapt substrate oxidation according to metabolic demand. Exercise increases fat oxidation responses in individuals living with obesity; however, limited research exists on the relationship between substrate oxi