Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ashley K. Brown"'
Autor:
Moujtaba Y. Kasmani, Paytsar Topchyan, Ashley K. Brown, Ryan J. Brown, Xiaopeng Wu, Yao Chen, Achia Khatun, Donia Alson, Yue Wu, Robert Burns, Chien-Wei Lin, Matthew R. Kudek, Jie Sun, Weiguo Cui
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Influenza virus infection causes increased morbidity and mortality in the elderly. Aging impairs the immune response to influenza, both intrinsically and because of altered interactions with endothelial and pulmonary epithelial cells. To cha
Externí odkaz:
https://doaj.org/article/3316c2e4f76a4dd280e12a2c2ed09272
Publikováno v:
Surgery (Oxford).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82212d90b714871ea6e2ed25e0d4f5ed
https://doi.org/10.1016/j.mpsur.2023.02.030
https://doi.org/10.1016/j.mpsur.2023.02.030
Autor:
Moujtaba Y Kasmani, Ashley E Ciecko, Ashley K Brown, Galina Petrova, Jack Gorski, Yi-Guang Chen, Weiguo Cui
Publikováno v:
Life science alliance. 5(10)
Type 1 diabetes (T1D) is an autoimmune disorder defined by CD8 T cell–mediated destruction of pancreatic β cells. We have previously shown that diabetogenic CD8 T cells in the islets of non-obese diabetic mice are phenotypically heterogeneous, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81bd3f52c53c2876fa94629778991a5
https://pubmed.ncbi.nlm.nih.gov/35667687
https://pubmed.ncbi.nlm.nih.gov/35667687
Autor:
Xu Zhang, Marissa J. Schafer, Brian R. Kotajarvi, Thomas A. White, Ashley K. Brown, Michelle Berning, Sarah Jachim, Steven R. Cummings, Kevin L. Greason, Rakesh M. Suri, Nathan K. LeBrasseur, Yi Zhu, Amanika Kumar, Charles J. Bruce, Russell P. Tracy, Elizabeth J. Atkinson, Zaira Aversa, Daniel L. Mazula
Publikováno v:
JCI Insight
Produced by senescent cells, the senescence-associated secretory phenotype (SASP) is a potential driver of age-related dysfunction. We tested whether circulating concentrations of SASP proteins reflect age and medical risk in humans. We first screene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d897e0a72020d6d36ea93ab667d8920c
https://doi.org/10.1172/jci.insight.133668
https://doi.org/10.1172/jci.insight.133668
Autor:
Vesselina M. Pearsall, Nathan K. LeBrasseur, Daniel L. Mazula, Marissa J. Schafer, Jordan D. Miller, Thomas A. White, Ashley K. Brown, Zaira Aversa, Aleksey V. Matveyenko, Grace C Verzosa, Elizabeth J. Atkinson, Leslie A. Smith
Publikováno v:
Aging Cell
Aging and obesity increase multimorbidity and disability risk, and determining interventions for reversing healthspan decline is a critical public health priority. Exercise and time‐restricted feeding (TRF) benefit multiple health parameters when i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e18a1c2683ecfbe99126b3c59675e90
https://doi.org/10.1111/acel.12966
https://doi.org/10.1111/acel.12966
Autor:
Weiguo Cui, Peter J. Volberding, Gang Xin, Moujtaba Y. Kasmani, Christine Nguyen, Achia Khatun, Eli Martinez, Ashley K. Brown, John A. Corbett, Jennifer S. Stancill
Publikováno v:
Cell reports
SUMMARY The immune response to a chronic viral infection is uniquely tailored to balance viral control and immunopathology. The role of myeloid cells in shaping the response to chronic viral infection, however, is poorly understood. We perform single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf5641474c5b5165909908c14bc3009
https://doi.org/10.1016/j.celrep.2021.109160
https://doi.org/10.1016/j.celrep.2021.109160
Autor:
Nicholas T. Meshkin, Elizabeth L. Johnson, Shane A. Perrine, Alexander Gow, Daniel Z. Radecki, Ashley K. Brown
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-18 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-18 (2018)
Despite concerted efforts over decades, the etiology of multiple sclerosis (MS) remains unclear. Autoimmunity, environmental-challenges, molecular mimicry and viral hypotheses have proven equivocal because early-stage disease is typically presymptoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab6c0838cc91b0879e290cd5d149f57
http://europepmc.org/articles/PMC6208344
http://europepmc.org/articles/PMC6208344
Autor:
Thomas A. White, Ashley K. Brown, Daniel L. Mazula, Jordan D. Miller, Carolyn M Roos, Bin Zhang, Richard A. Miller, Nathan K. LeBrasseur
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c29b548483c957c39aae0fd87cb6d97d
https://doi.org/10.1096/fasebj.2018.32.1_supplement.674.7
https://doi.org/10.1096/fasebj.2018.32.1_supplement.674.7
Autor:
Rangaprasad Sarangarajan, Christos Chinopoulos, Kenjiro Kami, Niven R. Narain, Luke J. Taus, Michael A. Kiebish, Roberto Flores, Laura M. Shelton, Ashley K. Brown, Julianna Khoury, Thomas N. Seyfried, Frank Glover, Tony E. Walshe
Publikováno v:
Biochimica et biophysica acta. Bioenergetics. 1859(9)
Succinate is known to act as an inflammatory signal in classically activated macrophages through stabilization of HIF-1α leading to IL-1β production. Relevant to this, hypoxia is known to drive succinate accumulation and release into the extracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d86f502ffa24ef5c22aa97273f1d90a
https://pubmed.ncbi.nlm.nih.gov/29580805
https://pubmed.ncbi.nlm.nih.gov/29580805
Autor:
Gabriel Martínez-Gálvez, William E. Matchett, Kirsten E. Coffman, Ashley K. Brown, Bruce F. Horazdovsky
Publikováno v:
Journal of College Science Teaching.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cc34ccf736c83ee6e9e6e46fd087a9f
https://doi.org/10.2505/4/jcst18_048_02_14
https://doi.org/10.2505/4/jcst18_048_02_14